D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 55 Citations 9,556 165 World Ranking 8607 National Ranking 2542
Biology and Biochemistry D-index 62 Citations 11,182 200 World Ranking 7163 National Ranking 3307

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Amino acid

His scientific interests lie mostly in Homocysteine, Biochemistry, Internal medicine, Methionine and Endocrinology. His Homocysteine research is multidisciplinary, relying on both Amino acid, Thioester and High-performance liquid chromatography, Chromatography, Ultrafiltration. Hieronim Jakubowski interconnects Aminoacyl tRNA synthetase, Transfer RNA, Amino Acyl-tRNA Synthetases and Toxicity in the investigation of issues within Amino acid.

He has researched Chromatography in several fields, including Metabolite and Escherichia coli. His Biochemistry research focuses on subjects like Thiolactone, which are linked to Biosynthesis. His Endocrinology study combines topics in areas such as Cystathionine beta synthase and Methylenetetrahydrofolate reductase.

His most cited work include:

  • Calcium-dependent human serum homocysteine thiolactone hydrolase. A protective mechanism against protein N-homocysteinylation. (356 citations)
  • Protein homocysteinylation: possible mechanism underlying pathological consequences of elevated homocysteine levels (311 citations)
  • Homocysteine Thiolactone and Protein Homocysteinylation in Human Endothelial Cells: Implications for Atherosclerosis (259 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Biochemistry, Homocysteine, Internal medicine, Endocrinology and Methionine. His research related to Amino acid, Transfer RNA, Enzyme, Aminoacyl tRNA synthetase and Lysine might be considered part of Biochemistry. His Homocysteine research includes elements of Thioester, Cystathionine beta synthase, Chromatography and Paraoxonase.

While the research belongs to areas of Internal medicine, he spends his time largely on the problem of PON1, intersecting his research to questions surrounding Lipoprotein and Cholesterol. His Endocrinology research is multidisciplinary, incorporating perspectives in Thiol, Vascular disease and Methylenetetrahydrofolate reductase. His Methionine research is multidisciplinary, incorporating elements of Epitope, Antigen, Methyltransferase and Metabolism.

He most often published in these fields:

  • Biochemistry (71.24%)
  • Homocysteine (62.66%)
  • Internal medicine (34.33%)

What were the highlights of his more recent work (between 2011-2021)?

  • Homocysteine (62.66%)
  • Internal medicine (34.33%)
  • Endocrinology (31.33%)

In recent papers he was focusing on the following fields of study:

Hieronim Jakubowski mainly focuses on Homocysteine, Internal medicine, Endocrinology, Biochemistry and Hyperhomocysteinemia. The concepts of his Homocysteine study are interwoven with issues in Vitamin B12, Toxicity, Genotype and Cystathionine beta synthase, Methionine. His Methionine study integrates concerns from other disciplines, such as Metabolism and Bacteria.

In his research on the topic of Internal medicine, Paraoxonase is strongly related with PON1. His research in Hyperhomocysteinemia intersects with topics in Metabolite, Molecular biology, Gene expression and Neurotoxicity. His work is dedicated to discovering how Amino acid, TRNA aminoacylation are connected with Genetic code and other disciplines.

Between 2011 and 2021, his most popular works were:

  • Paraoxonase 1 and homocysteine metabolism (68 citations)
  • Paraoxonase 1 and homocysteine metabolism (68 citations)
  • Quality control in tRNA charging (53 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Amino acid

His primary areas of investigation include Homocysteine, Internal medicine, Endocrinology, Hyperhomocysteinemia and Biochemistry. The study incorporates disciplines such as Genetic disorder, Human disease, Connective tissue, Protein structure function and Metabolism in addition to Homocysteine. As a part of the same scientific study, he usually deals with the Internal medicine, concentrating on Gastroenterology and frequently concerns with Plasminogen activator inhibitor-1, Cholesterol, Arterial stiffness and Obesity.

His studies in Endocrinology integrate themes in fields like Composition, Betaine and Trimethylglycine. Hieronim Jakubowski combines subjects such as Metabolite, Neurotoxicity, Gene expression and Neurodegeneration with his study of Hyperhomocysteinemia. Biochemistry and Chromatography are frequently intertwined in his study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Calcium-dependent human serum homocysteine thiolactone hydrolase. A protective mechanism against protein N-homocysteinylation.

Hieronim Jakubowski.
Journal of Biological Chemistry (2000)

530 Citations

Protein homocysteinylation: possible mechanism underlying pathological consequences of elevated homocysteine levels

Hieronim Jakubowski.
The FASEB Journal (1999)

456 Citations

Editing of errors in selection of amino acids for protein synthesis.

Hieronim Jakubowski;Emanuel Goldman.
Microbiological Research (1992)

404 Citations

Homocysteine Thiolactone and Protein Homocysteinylation in Human Endothelial Cells: Implications for Atherosclerosis

Hieronim Jakubowski;Li Zhang;Arlene Bardeguez;Abram Aviv.
Circulation Research (2000)

380 Citations

Metabolism of Homocysteine Thiolactone in Human Cell Cultures POSSIBLE MECHANISM FOR PATHOLOGICAL CONSEQUENCES OF ELEVATED HOMOCYSTEINE LEVELS

Hieronim Jakubowski.
Journal of Biological Chemistry (1997)

352 Citations

Molecular basis of homocysteine toxicity in humans.

Hieronim Jakubowski.
Cellular and Molecular Life Sciences (2004)

341 Citations

Mechanisms of homocysteine toxicity in humans

J. Perła-Kaján;T. Twardowski;Hieronim Jakubowski;Hieronim Jakubowski.
Amino Acids (2007)

320 Citations

Homocysteine Thiolactone: Metabolic Origin and Protein Homocysteinylation in Humans

Hieronim Jakubowski.
Journal of Nutrition (2000)

299 Citations

Pathophysiological Consequences of Homocysteine Excess

Hieronim Jakubowski.
Journal of Nutrition (2006)

294 Citations

Alternative pathways for editing non-cognate amino acids by aminoacyl-tRNA synthetases

Hieronim Jakubowski;Alan R.Fersht.
Nucleic Acids Research (1981)

224 Citations

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