World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
48
Citations
10508
World Ranking
15092
National Ranking
839

Overview

G. Michael Blackburn is a researcher affiliated with the University of Sheffield in the United Kingdom. Their work spans biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology, organic chemistry, molecular medicine, and pharmacology. Blackburn's contributions prominently address antibiotic resistance, antibiotics pharmacokinetics and efficacy, pharmaceutical and antibiotic environmental impacts, and chemical synthesis and analysis.

The scientist has contributed to the following recent papers:

  • Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers, 2020, Proceedings of the National Academy of Sciences
  • Mechanistic and Structural Insights into the Specificity and Biological Functions of Bacterial Sulfoglycosidases, 2022, ACS Catalysis
  • An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity, 2023, ACS Central Science
  • Octahedral Trifluoromagnesate, an Anomalous Metal Fluoride Species, Stabilizes the Transition State in a Biological Motor, 2021, ACS Catalysis
  • Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1, 2022, Communications Biology

Frequent co-authors collaborating with Blackburn include:

  • Yi Jin
  • Zhen Zhang
  • Patrick Baumann
  • Yuan He
  • Andrey V. Golovin

The researcher frequently publishes in these venues:

  • ACS Catalysis
  • Proceedings of the National Academy of Sciences
  • ACS Central Science
  • Communications Biology
  • Israel Journal of Chemistry

Blackburn's work is situated mainly within the following fields and topics:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Molecular Biology
  • Organic Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pollution
  • Antibiotic Resistance in Bacteria
  • Antibiotics Pharmacokinetics and Efficacy
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Chemical Synthesis and Analysis
  • Endoplasmic Reticulum Stress and Disease
  • Biochemical and Molecular Research
  • Protein Kinase Regulation and GTPase Signaling

Best Publications

  • Nucleic Acids in Chemistry and Biology

    Unknown

  • Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro.

    Julie C. Frith;Jukka Mönkkönen;G. Michael Blackburn;R. Graham G. Russell

  • Uracil-DNA glycosylase–DNA substrate and product structures: Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects

    Sudip S. Parikh;Gunter Walcher;Garry D. Jones;Geir Slupphaug

  • Uracil-DNA glycosylase acts by substrate autocatalysis.

    Aaron R. Dinner;Aaron R. Dinner;G. Michael Blackburn;Martin Karplus;Martin Karplus

  • The synthesis and metal binding characteristics of novel, isopolar phosphonate analogues of nucleotides

    Unknown

  • Why did Nature select phosphate for its dominant roles in biology

    Matthew W. Bowler;Matthew J. Cliff;Jonathan P. Waltho;G. Michael Blackburn

  • Antibiotic recognition by binuclear metallo-beta-lactamases revealed by X-ray crystallography.

    Jim Spencer;J Read;Richard B Sessions;S Howell

  • Derivatives of tamoxifen. Dependence of antiestrogenicity on the 4-substituent.

    McCague R;Leclercq G;Legros N;Goodman J

  • Incorporation of bisphosphonates into adenine nucleotides by amoebae of the cellular slime mould Dictyostelium discoideum

    Michael John Rogers;X Ji;R G Russell;G M Blackburn

  • Turnover-based in vitro selection and evolution of biocatalysts from a fully synthetic antibody library

    Sandro Cesaro-Tadic;Dimitrios Lagos;Dimitrios Lagos;Annemarie Honegger;James H Rickard

  • Isopolar vs Isosteric Phosphonate Analogues of Nucleotides

    G. Michael Blackburn;Fritz Eckstein;David E. Kent;Timothy D. Perrée

  • Transition State Analogue Structures of Human Phosphoglycerate Kinase Establish the Importance of Charge Balance in Catalysis

    Matthew J. Cliff;Matthew W. Bowler;Andrea Varga;James P. Marston

  • Toward antibody-directed "abzyme" prodrug therapy, ADAPT: carbamate prodrug activation by a catalytic antibody and its in vitro application to human tumor cell killing.

    Unknown

  • Anionic charge is prioritized over geometry in aluminum and magnesium fluoride transition state analogs of phosphoryl transfer enzymes.

    Nicola J Baxter;G Michael Blackburn;James P Marston;Andrea M Hounslow

  • Chemical polysialylation of human recombinant butyrylcholinesterase delivers a long-acting bioscavenger for nerve agents in vivo

    Denis G. Ilyushin;Ivan V. Smirnov;Ivan V. Smirnov;Alexey A. Belogurov;Igor A. Dyachenko

  • Metabolism of halogenated bisphosphonates by the cellular slime mould Dictyostelium discoideum.

    Michael John Rogers;R G Russell;G M Blackburn;M P Williamson

  • Three new β,γ-methylene analogues of adenosine triphosphate

    G. Michael Blackburn;David E. Kent;Friedrich Kolkmann

  • Alkaline Hydrolysis of Amide Bonds: Effect of Bond Twist and Nitrogen Pyramidalization

    Xabier Lopez;Jon Inaki Mujika;G. Michael Blackburn;Martin Karplus

  • Probing the molecular mechanism of action of co-repressor in the E.coli methionine repressor-operator complex using surface plasmon resonance (SPR)

    I. D. Parsons;B. Persson;Abdelaziz Mekhalfia;G. M. Blackburn

  • Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF 3 - rather than by phosphoranes

    Nicola J. Baxter;Matthew W. Bowler;Tooba Alizadeh;Matthew J. Cliff

  • Studies on selected transformations of some fluoromethanephosphonate esters

    G. Michael Blackburn;David Brown;Stephen J. Martin;Martin J. Parratt

  • A Trojan horse transition state analogue generated by MgF3- formation in an enzyme active site.

    Nicola J Baxter;Luis F Olguin;Marko Golicnik;Guoqiang Feng

  • Highly Potent Bisphosphonate Ligands for Phosphoglycerate Kinase

    Jakeman Dl;Ivory Aj;Williamson Mp;Blackburn Gm

  • Biochemical, Crystallographic and Mutagenic Characterization of Hint, the AMP-Lysine Hydrolase, with Novel Substrates and Inhibitors

    Agnieszka Krakowiak;Agnieszka Krakowiak;Helen C. Pace;G. Michael Blackburn;Martina Adams

  • Aqueous solutions containing amino acids and peptides. Part 13.—Enthalpy of dilution and osmotic coefficients of some N-acetyl amino acid amides and some N-acetyl peptide amides at 298.15 K

    G. Michael Blackburn;Terence H. Lilley;Elizabeth Walmsley

  • A novel synthesis of α- and γ- fluoroalkylphosphonates

    G. Michael Blackburn;David E. Kent

  • The Crystal Structure of Diadenosine Tetraphosphate Hydrolase from Caenorhabditis elegans in Free and Binary Complex Forms

    Scott Bailey;Svetlana E Sedelnikova;G.Michael Blackburn;Hend M Abdelghany

Frequent Co-Authors

Jonathan P. Waltho
Jonathan P. Waltho University of Sheffield
Terence H. Lilley
Terence H. Lilley University of Sheffield
Charles Brenner
Charles Brenner City Of Hope National Medical Center
Andreas Plückthun
Andreas Plückthun University of Zurich
David W. Rice
David W. Rice University of Sheffield
Yufen Zhao
Yufen Zhao Xiamen University
Michael P. Williamson
Michael P. Williamson University of Sheffield
Nicholas H. Williams
Nicholas H. Williams University of Sheffield
Michael J. Rogers
Michael J. Rogers Garvan Institute of Medical Research
Wojciech J. Stec
Wojciech J. Stec Polish Academy of Sciences

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring online degree options related to Chemistry can open doors to diverse and rewarding careers. For those interested in law enforcement or legal fields, an how much is a criminal justice degree can help you budget your education effectively. Many institutions offer an accredited online criminal justice associate degree, providing flexible pathways into criminal justice careers.

Similarly, if you are considering supplementing your Chemistry background with knowledge of legal systems, understanding paralegal salary potential can help you gauge the benefits of pursuing paralegal studies alongside science.

For Chemistry graduates aiming at the biotech or pharmaceutical industries, learning how to get into pharmaceutical sales is a practical step towards a lucrative career. This path combines scientific expertise with communication skills to bridge the gap between production and market.

Overall, integrating knowledge from related fields through online degrees can enhance career prospects, making it easier to carve a unique professional niche in Chemistry and allied sectors.

Best Scientists Citing G. Michael Blackburn

Trending Scientists