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Charles Brenner

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
19555
World Ranking
6585
National Ranking
3068

Charles Brenner publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Charles Brenner sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 224 publications — 59th percentile

59% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Charles Brenner D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Charles Brenner sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 71 D-Index — 67th percentile

67% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Charles Brenner is affiliated with the City Of Hope National Medical Center in the United States. Their research focuses primarily on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with contributions also spanning subfields such as Physiology, Molecular Biology, Geriatrics and Gerontology, Epidemiology, and Oncology.

The scientist has contributed to several key topics within the biomedical sciences, including:

  • Sirtuins and Resveratrol in Medicine
  • Calcium signaling and nucleotide metabolism
  • Adipose Tissue and Metabolism
  • Genetics, Aging, and Longevity in Model Organisms
  • Autophagy in Disease and Therapy
  • Mitochondrial Function and Pathology
  • PARP inhibition in cancer therapy

Charles Brenner's publication record includes multiple papers in top-tier journals. Recent notable papers include:

  • "Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages," 2020, Nature Metabolism
  • "Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy," 2020, Cell Metabolism
  • "Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity," 2020, Journal of Biological Chemistry
  • "NAD+ Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging," 2020, Molecular Cell
  • "Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study," 2023, Science Advances

The scientist frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Metabolism, Journal of Biological Chemistry, Cell Metabolism, and Science. Their most common publication venue is bioRxiv with 10 publications, followed by Nature Metabolism with 6.

Collaborative work is a significant part of their scholarly output. Frequent coauthors include:

  • Mark S. Schmidt
  • Eija Pirinen
  • Collin D. Heer
  • Antti Hakkarainen
  • Nina Lundbom

Best Publications

  • p53 Activation by Knockdown Technologies

    Mara E Robu;Jon D Larson;Aidas Nasevicius;Aidas Nasevicius;Soraya Beiraghi

  • NAD+ metabolism in health and disease.

    Peter Belenky;Katrina L. Bogan;Charles Brenner

  • Discoveries of Nicotinamide Riboside as a Nutrient and Conserved NRK Genes Establish a Preiss-Handler Independent Route to NAD+ in Fungi and Humans

    Pawel Bieganowski;Charles Brenner

  • Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition

    Katrina L. Bogan;Charles Brenner

  • Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

    Samuel A. J. Trammell;Mark S. Schmidt;Benjamin J. Weidemann;Philip Redpath

  • Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast.

    Ainslie B. Parsons;Andres Lopez;Inmar E. Givoni;David E. Williams

  • The nitrilase superfamily: classification, structure and function

    Helen C Pace;Charles Brenner

  • Nicotinamide Riboside Promotes Sir2 Silencing and Extends Lifespan via Nrk and Urh1/Pnp1/Meu1 Pathways to NAD+

    Peter Belenky;Frances G. Racette;Katrina L. Bogan;Julie M. McClure

  • GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction

    Ikuko Miyajima;Masato Nakafuku;Naoki Nakayama;Charles Brenner

  • Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures.

    Yasir S. Elhassan;Yasir S. Elhassan;Katarina Kluckova;Rachel S. Fletcher;Mark S. Schmidt

  • Hint, Fhit, and GalT: function, structure, evolution, and mechanism of three branches of the histidine triad superfamily of nucleotide hydrolases and transferases.

    Charles Brenner

  • NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

    Joanna Ratajczak;Magali Joffraud;Samuel A. J. Trammell;Rosa Ras

  • Nicotinamide Riboside Opposes Type 2 Diabetes and Neuropathy in Mice

    Samuel A.J. Trammell;Benjamin J. Weidemann;Ankita Chadda;Matthew S. Yorek

  • Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging.

    Shogo Sato;Guiomar Solanas;Francisca Oliveira Peixoto;Leonardo Bee

  • Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice

    Sarah J. Mitchell;Michel Bernier;Miguel A. Aon;Sonia Cortassa

  • Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy

    Nicolas Diguet;Samuel A.J. Trammell;Cynthia Tannous;Cynthia Tannous;Robin Deloux;Robin Deloux

  • Catalysis in the nitrilase superfamily.

    Charles Brenner

  • Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages.

    Anthony J. Covarrubias;Anthony J. Covarrubias;Abhijit Kale;Rosalba Perrone;Jose Alberto Lopez-Dominguez

  • Structural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 protease.

    Charles Brenner;Robert S. Fuller

  • Arabidopsis VTC2 Encodes a GDP-l-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants

    Carole L. Linster;Tara A. Gomez;Kathryn C. Christensen;Lital N. Adler

Frequent Co-Authors

Eric Verdin
Eric Verdin Buck Institute for Research on Aging
Robert S. Fuller
Robert S. Fuller University of Michigan–Ann Arbor
Hiroshi Okamoto
Hiroshi Okamoto University of Tokyo
Kay Huebner
Kay Huebner The Ohio State University
Melanie Ott
Melanie Ott Gladstone Institutes
Haruhiro Higashida
Haruhiro Higashida Kanazawa University
Judith Campisi
Judith Campisi Buck Institute for Research on Aging
Stanley Perlman
Stanley Perlman University of Iowa
Stephen R. Quake
Stephen R. Quake Stanford University
Carlo M. Croce
Carlo M. Croce The Ohio State University

External Links

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