World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
81
Citations
30347
World Ranking
3814
National Ranking
1888

Research.com Recognitions

  • 2007 - Hellman Fellow

Overview

Melanie Ott is affiliated with the Gladstone Institutes in the United States and has a significant body of research focused on infectious diseases, molecular biology, and epidemiology. Their work spans several intersecting fields, including medicine, biochemistry, genetics, and molecular biology, with a strong emphasis on viral research.

The main topics in Melanie Ott's research include:

  • SARS-CoV-2 and COVID-19 Research
  • SARS-CoV-2 detection and testing
  • COVID-19 Clinical Research Studies
  • CRISPR and Genetic Engineering
  • HIV Research and Treatment
  • Bacteriophages and microbial interactions
  • Viral gastroenteritis research and epidemiology

Melanie Ott has contributed extensively to the literature, with a notable presence in high-impact journals. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell
  • PLoS Pathogens
  • Nature
  • mBio

The scientist's recent papers highlight work primarily on SARS-CoV-2 and related biomedical research:

  • "A SARS-CoV-2 protein interaction map reveals targets for drug repurposing," 2020, Nature
  • "The Global Phosphorylation Landscape of SARS-CoV-2 Infection," 2020, Cell
  • "Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy," 2020, Cell
  • "Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant," 2021, Cell
  • "An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike," 2020, Science

Collaborative work is an integral part of Melanie Ott's research approach. The most frequent coauthors include:

  • G. Renuka Kumar
  • Taha Y. Taha
  • Nevan J. Krogan
  • Mir M. Khalid
  • Irene P. Chen

Their research covers several subfields of study, emphasizing infectious diseases, molecular biology, epidemiology, immunology, and virology. These areas reflect a broad yet focused interest in understanding and combating infectious agents through molecular and clinical research.

Melanie Ott was recognized with the Hellman Fellow award in 2007, an acknowledgment of their contributions within the scientific community.

Best Publications

  • A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

    David E. Gordon;Gwendolyn M. Jang;Mehdi Bouhaddou;Jiewei Xu

  • The Global Phosphorylation Landscape of SARS-CoV-2 Infection.

    Mehdi Bouhaddou;Danish Memon;Bjoern Meyer;Kris M. White

  • Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

    Sang Won Min;Seo Hyun Cho;Yungui Zhou;Sebastian Schroeder

  • Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a and mobile phone microscopy.

    Parinaz Fozouni;Sungmin Son;María Díaz de León Derby;Gavin J. Knott;Gavin J. Knott

  • Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

    David E. Gordon;Joseph Hiatt;Mehdi Bouhaddou;Veronica V. Rezelj

  • 50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyond

    Eric Verdin;Melanie Ott

  • Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation.

    C. Van Lint;S. Emiliani;M. Ott;E. Verdin

  • The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide–dependent deacetylase

    Björn Schwer;Brian J. North;Roy A. Frye;Melanie Ott

  • International AIDS Society global scientific strategy: towards an HIV cure 2016

    Steven G Deeks;Sharon R Lewin;Anna Laura Ross;Jintanat Ananworanich

  • Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant.

    Xianding Deng;Miguel A. Garcia-Knight;Mir M. Khalid;Venice Servellita

  • SIRT1 regulates HIV transcription via Tat deacetylation.

    Sara Pagans;Angelika Pedal;Brian J North;Katrin Kaehlcke

  • An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

    Michael Schoof;Bryan Faust;Reuben A. Saunders;Smriti Sangwan

  • Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1.

    Eva Herker;Charles Harris;Céline Hernandez;Arnaud Carpentier

  • Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses.

    Ruofan Wang;Camille R. Simoneau;Jessie Kulsuptrakul;Mehdi Bouhaddou

  • Significantly improved PCR-based clonality testing in B-cell malignancies by use of multiple immunoglobulin gene targets: Report of the BIOMED-2 Concerted Action BHM4-CT98-3936

    P. A. S. Evans;Ch Pott;P. J. T. A. Groenen;G. Salles

  • Lysine Acetylation Goes Global: From Epigenetics to Metabolism and Therapeutics

    Ibraheem Ali;Ryan J. Conrad;Eric Verdin;Melanie Ott

  • Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activity

    Melanie Ott;Martina Schnölzer;Jerry Garnica;Wolfgang Fischle

  • Improved reliability of lymphoma diagnostics via PCR-based clonality testing: report of the BIOMED-2 Concerted Action BHM4-CT98-3936.

    J H J M van Krieken;A W Langerak;E A Macintyre;M Kneba

  • The Control of HIV Transcription: Keeping RNA Polymerase II on Track

    Melanie Ott;Matthias Geyer;Qiang Zhou

  • Erratum to Acetylation of tau inhibits its degradation and contributes to tauopathy

    Sang Won Min;Seo Hyun Cho;Yungui Zhou;Sebastian Schroeder

Frequent Co-Authors

Eric Verdin
Eric Verdin Buck Institute for Research on Aging
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco
Martina Schnölzer
Martina Schnölzer German Cancer Research Center
Gert Fricker
Gert Fricker Heidelberg University
Warner C. Greene
Warner C. Greene University of California, San Francisco
Adolfo García-Sastre
Adolfo García-Sastre Icahn School of Medicine at Mount Sinai
Katherine S. Pollard
Katherine S. Pollard University of California, San Francisco
Robert V. Farese
Robert V. Farese Harvard University
Jeffrey R. Johnson
Jeffrey R. Johnson Icahn School of Medicine at Mount Sinai
Carine Van Lint
Carine Van Lint Université Libre de Bruxelles

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