World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
106
Citations
36425
World Ranking
431
National Ranking
30

Medicine

D-Index
107
Citations
38054
World Ranking
6307
National Ranking
611

Research.com Recognitions

  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Mauro Giacca is affiliated with King's College London in the United Kingdom. Their research spans multiple fields within medicine, focusing extensively on molecular biology and cardiology. Their work frequently addresses infectious diseases, surgery, and cancer research.

The scientist has contributed to a substantial body of research including 194 publications in medicine and 158 in biochemistry, genetics, and molecular biology. Their subfield expertise includes molecular biology with 108 publications, cardiology and cardiovascular medicine with 71, infectious diseases and surgery with 28 each, and cancer research with 21.

Giacca's research covers a range of prominent topics, notably:

  • Congenital heart defects research
  • Cardiac fibrosis and remodeling
  • Viral infections and immunology research
  • COVID-19 clinical research studies
  • Cardiomyopathy and myosin studies
  • Virus-based gene therapy research
  • SARS-CoV-2 and COVID-19 research

Their recent publications include:

  • "The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets" (2021, Nature Microbiology)
  • "Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia" (2021, Nature)
  • "Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology" (2020, EBioMedicine)
  • "Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function" (2020, Cardiovascular Research)
  • "SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care" (2021, Nature Communications)

Giacca has collaborated extensively with several co-authors, including:

  • Lorena Zentilin
  • Serena Zacchigna
  • Luca Braga
  • Antonio Cannatà
  • Gianfranco Sinagra

The scientist's work is frequently published in leading venues such as Cardiovascular Research, bioRxiv (Cold Spring Harbor Laboratory), European Heart Journal, Nature Cardiovascular Research, and Nature Communications.

Among professional recognitions, Mauro Giacca is a Fellow of The Academy of Medical Sciences, United Kingdom.

Best Publications

  • Functional screening identifies miRNAs inducing cardiac regeneration

    Ana Eulalio;Miguel Mano;Matteo Dal Ferro;Matteo Dal Ferro;Lorena Zentilin

  • Anti-PlGF Inhibits Growth of VEGF(R)-Inhibitor-Resistant Tumors without Affecting Healthy Vessels

    Christian Fischer;Bart Jonckx;Massimiliano Mazzone;Serena Zacchigna

  • The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response.

    Bao N. Puente;Wataru Kimura;Shalini A. Muralidhar;Jesung Moon

  • Internalization of HIV-1 Tat Requires Cell Surface Heparan Sulfate Proteoglycans

    Mudit Tyagi;Marco Rusnati;Marco Presta;Mauro Giacca

  • The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets.

    Thomas P. Peacock;Daniel H. Goldhill;Jie Zhou;Laury Baillon

  • Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins.

    Antonio Fittipaldi;Aldo Ferrari;Monica Zoppé;Caterina Arcangeli

  • Identification of HSP90 inhibitors as a novel class of senolytics

    Heike Fuhrmann-Stroissnigg;Yuan Yuan Ling;Jing Zhao;Sara J. McGowan

  • Caveolae-mediated internalization of extracellular HIV-1 tat fusion proteins visualized in real time.

    Aldo Ferrari;Vittorio Pellegrini;Caterina Arcangeli;Antonio Fittipaldi

  • Cardiomyocyte regeneration: A consensus statement

    Thomas Eschenhagen;Roberto Bolli;Thomas Braun;Loren J. Field

  • Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia.

    Luca Braga;Hashim Ali;Ilaria Secco;Elena Chiavacci

  • Familial dilated cardiomyopathy: Evidence for genetic and phenotypic heterogeneity

    Luisa Mestroni;Chiara Rocco;Dario Gregori;Gianfranco Sinagra

  • MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs

    Khatia Gabisonia;Giulia Prosdocimo;Giovanni Donato Aquaro;Lucia Carlucci

  • Familial dilated cardiomyopathy: evidence for genetic and phenotypic heterogeneity. Heart Muscle Disease Study Group.

    L Mestroni;C Rocco;D Gregori;G Sinagra

  • Vascular endothelial growth factor stimulates skeletal muscle regeneration in Vivo

    Nikola Arsic;Serena Zacchigna;Lorena Zentilin;Genaro Ramirez-Correa

  • Virus-mediated gene delivery for human gene therapy.

    Mauro Giacca;Serena Zacchigna

  • Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat.

    Michelle Silhol;Mudit Tyagi;Mauro Giacca;Bernard Lebleu

  • HIV-1 Tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter

    Giuseppe Marzio;Mudit Tyagi;Maria Ines Gutierrez;Mauro Giacca

  • Nuclear architecture dictates HIV-1 integration site selection

    Bruna Marini;Attila Kertesz-Farkas;Hashim Ali;Bojana Lucic;Bojana Lucic

  • Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology

    Rossana Bussani;Edoardo Schneider;Lorena Zentilin;Chiara Collesi

  • A novel procedure for quantitative polymerase chain reaction by coamplification of competitive templates

    Silvia Diviacco;Paolo Norio;Lorena Zentilin;Stefano Menzo

Frequent Co-Authors

Lorena Zentilin
Lorena Zentilin International Centre for Genetic Engineering and Biotechnology
Serena Zacchigna
Serena Zacchigna International Centre for Genetic Engineering and Biotechnology
Gianfranco Sinagra
Gianfranco Sinagra University of Trieste
Arturo Falaschi
Arturo Falaschi International Centre for Genetic Engineering and Biotechnology
Giuseppe Biamonti
Giuseppe Biamonti National Research Council (CNR)
Silvano Riva
Silvano Riva University of Pavia
Vittorio Pellegrini
Vittorio Pellegrini Italian Institute of Technology
Umberto Tirelli
Umberto Tirelli National Institutes of Health
Stephane Heymans
Stephane Heymans Maastricht University
Francesco Squadrito
Francesco Squadrito University of Messina

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