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Seppo Ylä-Herttuala

Seppo Ylä-Herttuala

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Biology and Biochemistry
Finland
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
144
Citations
76309
World Ranking
228
National Ranking
2

Medicine

D-Index
144
Citations
76349
World Ranking
1446
National Ranking
17

Seppo Ylä-Herttuala publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Seppo Ylä-Herttuala sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 955 publications — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Seppo Ylä-Herttuala D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Seppo Ylä-Herttuala sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 144 D-Index — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Finland Leader Award
  • 2025 - Research.com Biology and Biochemistry in Finland Leader Award
  • 2023 - Research.com Biology and Biochemistry in Finland Leader Award
  • 2022 - Research.com Biology and Biochemistry in Finland Leader Award

Overview

Seppo Ylä-Herttuala is affiliated with the University of Eastern Finland in Finland and has a research portfolio primarily focused on medicine and biochemistry, genetics, and molecular biology.

Their work spans several subfields, including molecular biology, surgery, cardiology and cardiovascular medicine, genetics, and cancer research.

Main research topics include virus-based gene therapy research, angiogenesis and VEGF in cancer, CAR-T cell therapy research, atherosclerosis and cardiovascular diseases, cancer-related molecular mechanisms, bladder and urothelial cancer treatments, and microRNA in disease regulation.

Frequent co-authors in their research include Minna U. Kaikkonen, Johanna P. Laakkonen, Nihay Laham-Karam, Tiit Örd, and Juha Hartikainen.

Their publications are often featured in several notable venues. The most frequent publication venues are:

  • European Heart Journal
  • Scientific Reports
  • Human Gene Therapy
  • Arteriosclerosis Thrombosis and Vascular Biology
  • The Journal of Urology

Selected recent papers authored or co-authored by Seppo Ylä-Herttuala include:

  • "Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics" (2020) published in Circulation Research
  • "Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial" (2020) published in The Lancet Oncology
  • "BMP6/TAZ-Hippo signaling modulates angiogenesis and endothelial cell response to VEGF" (2020) published in Angiogenesis
  • "Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci" (2021) published in Circulation Research
  • "MicroRNA-15b Targets VEGF and Inhibits Angiogenesis in Proliferative Diabetic Retinopathy" (2020) published in The Journal of Clinical Endocrinology & Metabolism

Best Publications

  • Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

    Seppo Yla-Herttuala;Wulf Palinski;Michael E. Rosenfeld;Sampath Parthasarathy

  • Low density lipoprotein undergoes oxidative modification in vivo

    Wulf Palinski;Michael E. Rosenfeld;Seppo Yla-Herttuala;Geoff C. Gurtner

  • Autoantibody against oxidised LDL and progression of carotid atherosclerosis.

    Salonen Jt;Ylä-Herttuala S;Yamamoto R;Butler S

  • Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions.

    Seppo Ylä-Herttuala;Beth A. Lipton;Michael E. Rosenfeld;Terttu Särkioja

  • Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3.

    Taija Mäkinen;Lotta Jussila;Tanja Veikkola;Terhi Karpanen

  • Vascular Endothelial Growth Factor C Promotes Tumor Lymphangiogenesis and Intralymphatic Tumor Growth

    Terhi Karpanen;Mikala Egeblad;Marika J. Karkkainen;Hajime Kubo

  • Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

    Tuomas Tammela;Georgia Zarkada;Elisabet Wallgard;Aino Murtomäki

  • Safety and Feasibility of Catheter-Based Local Intracoronary Vascular Endothelial Growth Factor Gene Transfer in the Prevention of Postangioplasty and In-Stent Restenosis and in the Treatment of Chronic Myocardial Ischemia Phase II Results of the Kuopio Angiogenesis Trial (KAT)

    Marja Hedman;Juha Hartikainen;Mikko Syvänne;Joachim Stjernvall

  • Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor

    Tatiana V. Petrova;Taija Mäkinen;Tomi P. Mäkelä;Janna Saarela

  • Rabbit and human atherosclerotic lesions contain IgG that recognizes epitopes of oxidized LDL.

    S Ylä-Herttuala;W Palinski;S W Butler;S Picard

  • Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein.

    Wulf Palinski;Seppo Ylä-Herttuala;Michael E. Rosenfeld;Susan W. Butler

  • Suppression of Tumor Lymphangiogenesis and Lymph Node Metastasis by Blocking Vascular Endothelial Growth Factor Receptor 3 Signaling

    Yulong He;Ken Ichi Kozaki;Terhi Karpanen;Katsumi Koshikawa

  • A model for gene therapy of human hereditary lymphedema

    Marika J. Karkkainen;Anne Saaristo;Lotta Jussila;Kaisa A. Karila

  • Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits.

    M E Rosenfeld;W Palinski;S Ylä-Herttuala;S Butler

  • Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation

    Peter Baluk;Tuomas Tammela;Erin Ator;Natalya Lyubynska

  • Biology of vascular endothelial growth factors

    Himadri Roy;Shalini Bhardwaj;Seppo Ylä-Herttuala

  • Vascular endothelial growth factors: biology and current status of clinical applications in cardiovascular medicine.

    Seppo Ylä-Herttuala;Tuomas T. Rissanen;Ismo Vajanto;Juha Hartikainen

  • History of gene therapy

    Thomas Wirth;Nigel Parker;Seppo Ylä-Herttuala

  • Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis

    Tatiana V Petrova;Terhi Karpanen;Camilla Norrmén;Russell Mellor

  • Human gene therapy

    Ylä-Herttuala S;Ollikainen A;Vapalahti M

Frequent Co-Authors

Kari Alitalo
Kari Alitalo University of Helsinki
Juhani Knuuti
Juhani Knuuti Turku University Hospital
Mikko Hiltunen
Mikko Hiltunen University of Eastern Finland
Anna-Liisa Levonen
Anna-Liisa Levonen University of Eastern Finland
Tuomas Tammela
Tuomas Tammela Memorial Sloan Kettering Cancer Center
Olli Gröhn
Olli Gröhn University of Eastern Finland
Markku S. Kulomaa
Markku S. Kulomaa Tampere University
Veli-Matti Kosma
Veli-Matti Kosma University of Eastern Finland
Markku Laakso
Markku Laakso University of Eastern Finland
Joseph L. Witztum
Joseph L. Witztum University of California, San Diego

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