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D-Index
119
Citations
43970
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3936
National Ranking
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Overview

Sotirios Tsimikas is affiliated with the University of California, San Diego in the United States. The primary fields of study in their research include Medicine and Biochemistry, Genetics and Molecular Biology, with significant work in Surgery, Cardiology and Cardiovascular Medicine, Endocrinology, Diabetes and Metabolism, Molecular Biology, and Immunology.

The scientist's research largely focuses on topics related to lipoproteins and cardiovascular health, diabetes, cardiovascular risks associated with lipoproteins, lipid metabolism and disorders, atherosclerosis and cardiovascular diseases, cancer related to lipids and metabolism, antiplatelet therapy and cardiovascular diseases, and cardiac valve diseases and treatments.

Frequent publication venues where Tsimikas's work has appeared include the Journal of the American College of Cardiology, Atherosclerosis, Circulation, Journal of Clinical Lipidology, and the European Heart Journal.

Collaborators frequently working with Tsimikas include Joseph L. Witztum, Calvin Yeang, Harpreet Bhatia, Veronica Alexander, and Ewa Karwatowska-Prokopczuk.

Representative recent publications by Sotirios Tsimikas include:

  • Lipoprotein(a) Reduction in Persons with Cardiovascular Disease, 2020, New England Journal of Medicine
  • Effect of Alirocumab on Lipoprotein(a) and Cardiovascular Risk After Acute Coronary Syndrome, 2020, Journal of the American College of Cardiology
  • Vupanorsen, an N-acetyl galactosamine-conjugated antisense drug to ANGPTL3 mRNA, lowers triglycerides and atherogenic lipoproteins in patients with diabetes, hepatic steatosis, and hypertriglyceridaemia, 2020, European Heart Journal
  • Efficacy and safety of volanesorsen in patients with multifactorial chylomicronaemia (COMPASS): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial, 2021, The Lancet Diabetes & Endocrinology
  • Lipoprotein(a) lowering by alirocumab reduces the total burden of cardiovascular events independent of low-density lipoprotein cholesterol lowering: ODYSSEY OUTCOMES trial, 2020, European Heart Journal

Best Publications

  • Oxidized Phospholipids, Lp(a) Lipoprotein, and Coronary Artery Disease

    Sotirios Tsimikas;Emmanouil S. Brilakis;Elizabeth R. Miller;Joseph P. McConnell

  • A Test in Context: Lipoprotein(a): Diagnosis, Prognosis, Controversies, and Emerging Therapies

    Sotirios Tsimikas

  • Lipoprotein(a) Reduction in Persons with Cardiovascular Disease.

    Tsimikas S;Karwatowska-Prokopczuk E;Gouni-Berthold I;Tardif Jc

  • Oxidation-Specific Epitopes Are Danger-Associated Molecular Patterns Recognized by Pattern Recognition Receptors of Innate Immunity

    Yury I. Miller;Soo Ho Choi;Philipp Wiesner;Longhou Fang

  • Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials

    Nicholas J Viney;Julian C van Capelleveen;Richard S Geary;Shuting Xia

  • Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses

    Nathanael J. Spann;Lana X. Garmire;Jeffrey G. McDonald;David S. Myers

  • Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides

    Mark J. Graham;Richard G. Lee;Teresa A. Brandt;Li-Jung Tai

  • Complement factor H binds malondialdehyde epitopes and protects from oxidative stress

    David Weismann;Karsten Hartvigsen;Karsten Hartvigsen;Karsten Hartvigsen;Nadine Lauer;Keiryn L. Bennett

  • The role of oxidized phospholipids in atherosclerosis

    Judith A. Berliner;Norbert Leitinger;Sotirios Tsimikas

  • Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study

    Sotirios Tsimikas;Sotirios Tsimikas;Nicholas J Viney;Steven G Hughes;Walter Singleton

  • Atherogenic Lipids and Lipoproteins Trigger CD36-TLR2-Dependent Apoptosis in Macrophages Undergoing Endoplasmic Reticulum Stress

    Tracie A. Seimon;Marissa J. Nadolski;Xianghai Liao;Jorge Magallon

  • Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

    Xuchu Que;Ming Yow Hung;Ming Yow Hung;Calvin Yeang;Ayelet Gonen

  • Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans

    Fleur M. van der Valk;Siroon Bekkering;Jeffrey Kroon;Calvin Yeang

  • Baseline and on-statin treatment lipoprotein(a) levels for prediction of cardiovascular events: individual patient-data meta-analysis of statin outcome trials

    Peter Willeit;Peter Willeit;Paul M Ridker;Paul J Nestel;John Simes

  • Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes.

    Sotirios Tsimikas;Claes Bergmark;Reinaldo W Beyer;Raj Patel

  • Volanesorsen and triglyceride levels in familial chylomicronemia syndrome

    Joseph L Witztum;Daniel Gaudet;Steven D Freedman;Veronica J Alexander

  • Deficiency of cathepsin S reduces atherosclerosis in LDL receptor–deficient mice

    Galina K. Sukhova;Yaou Zhang;Jie Hong Pan;Youichiro Wada

  • C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients.

    Sotirios Tsimikas;James T. Willerson;Paul M. Ridker

  • A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma.

    Claes Bergmark;Asheesh Dewan;Alexina Orsoni;Esther Merki

  • Clinical utility of inflammatory markers and advanced lipoprotein testing: advice from an expert panel of lipid specialists.

    Michael H. Davidson;Christie M. Ballantyne;Terry A. Jacobson;Vera A. Bittner

Frequent Co-Authors

Joseph L. Witztum
Joseph L. Witztum University of California, San Diego
Christoph J. Binder
Christoph J. Binder Medical University of Vienna
Anthony N. DeMaria
Anthony N. DeMaria University of California, San Diego
Richard S. Geary
Richard S. Geary Ionis Pharmaceuticals (United States)
Erik S.G. Stroes
Erik S.G. Stroes University of Amsterdam
Yury I. Miller
Yury I. Miller University of California, San Diego
Zahi A. Fayad
Zahi A. Fayad Icahn School of Medicine at Mount Sinai
Peter Willeit
Peter Willeit Innsbruck Medical University
Stefan Kiechl
Stefan Kiechl Innsbruck Medical University
Santica M. Marcovina
Santica M. Marcovina University of Washington

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