World's Best Scientists 2026 revealed!
Michael Detmar

Michael Detmar

Award Badge
Medicine
Switzerland
2023

D-Index & Metrics

Medicine

D-Index
118
Citations
61616
World Ranking
4007
National Ranking
50

Research.com Recognitions

  • 2023 - Research.com Medicine in Switzerland Leader Award
  • 2015 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Internal Medicine and Dermatology

Overview

Michael Detmar is affiliated with ETH Zurich in Switzerland and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research portfolio includes a significant focus on oncology, molecular biology, immunology, cancer research, and surgery.

The scientist's work mainly revolves around key topics such as:

  • Lymphatic System and Diseases
  • Single-cell and spatial transcriptomics
  • Cancer Immunotherapy and Biomarkers
  • Cancer Cells and Metastasis
  • Cancer-related molecular mechanisms research
  • Psoriasis: Treatment and Pathogenesis
  • Wound Healing and Treatments

Michael Detmar's recent scholarly output includes the following papers:

  • "Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes" (2020, PLoS Biology)
  • "Lymphatic vessels in cancer" (2022, Physiological Reviews)
  • "Open pathways for cerebrospinal fluid outflow at the cribriform plate along the olfactory nerves" (2023, EBioMedicine)
  • "Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses" (2021, Cancer Research)
  • "Mechanisms of breast cancer metastasis" (2021, Clinical & Experimental Metastasis)

Frequent collaborators include:

  • Carlotta Tacconi (20 publications)
  • Lothar C. Dieterich (18 publications)
  • Yuliang He (13 publications)
  • Luca Ducoli (10 publications)
  • Epameinondas Gousopoulos (7 publications)

Michael Detmar's work is often published in the following venues:

  • Cells (5 publications)
  • Nature Communications (4 publications)
  • Journal of Investigative Dermatology (4 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (3 publications)
  • Zenodo (CERN European Organization for Nuclear Research) (3 publications)

In 2015, Michael Detmar received recognition from the German National Academy of Sciences Leopoldina for contributions in internal medicine and dermatology.

Best Publications

  • Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.

    H. F. Dvorak;L. F. Brown;M. Detmar;A. M. Dvorak

  • Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

    Mihaela Skobe;Thomas Hawighorst;David G. Jackson;Remko Prevo

  • A promoter-level mammalian expression atlas

    Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie

  • A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

    Aleksanteri Aspelund;Salli Antila;Steven T. Proulx;Tine Veronica Karlsen

  • Standard classification of rosacea: Report of the National Rosacea Society Expert Committee on the Classification and Staging of Rosacea

    Jonathan Wilkin;Mark Dahl;Michael Detmar;Lynn Drake

  • An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype

    Jeffrey T. Wigle;Jeffrey T. Wigle;Natasha Harvey;Michael Detmar;Irina Lagutina

  • Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis.

    Joanna Stanczyk;Deena M. Leslie Pedrioli;Fabia Brentano;Olga Sanchez-Pernaute

  • Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis

    Michael Detmar;Lawrence F. Brown;Kevin P. Claffey;Kiang-Teck Yeo

  • VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis

    S. Hirakawa;S. Kodama;R. Kunstfeld;K. Kajiya

  • Control of hair growth and follicle size by VEGF-mediated angiogenesis

    Kiichiro Yano;Lawrence F. Brown;Michael Detmar

  • Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin.

    D R Senger;S R Ledbetter;K P Claffey;A Papadopoulos-Sergiou

  • Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice.

    Michael Detmar;Lawrence F. Brown;Michael P. Schön;Brett M. Elicker

  • T1α/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema

    Vivien Schacht;Maria I. Ramirez;Young Kwon Hong;Satoshi Hirakawa

  • TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays.

    Tobias Gebäck;Martin Michael Peter Schulz;Petros Koumoutsakos;Michael Detmar

  • Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins.

    Donald R. Senger;Kevin P. Claffey;Julie E. Benes;Carole A. Perruzzi

  • Up-Regulation of the Lymphatic Marker Podoplanin, a Mucin-Type Transmembrane Glycoprotein, in Human Squamous Cell Carcinomas and Germ Cell Tumors

    Vivien Schacht;Soheil S. Dadras;Louise A. Johnson;David G. Jackson

  • Vascular Permeability Factor/Vascular Endothelial Growth Factor Induces Lymphangiogenesis as well as Angiogenesis

    Janice A. Nagy;Eliza Vasile;Dian Feng;Christian Sundberg

  • VEGF-C–induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites

    Satoshi Hirakawa;Lawrence F. Brown;Shohta Kodama;Karri Paavonen

  • Vascular permeability factor/vascular endothelial growth factor:A multifunctional angiogenic cytokine

    L. F. Brown;M. Detmar;K. Claffey;J. A. Nagy

  • Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis

    Michael Detmar;Lawrence F. Brown;Kevin P. Claffey;Kiang-Teck Yeo

Frequent Co-Authors

Lawrence F. Brown
Lawrence F. Brown Beth Israel Deaconess Medical Center
Young-Kwon Hong
Young-Kwon Hong University of Southern California
Constantin E. Orfanos
Constantin E. Orfanos Freie Universität Berlin
Kevin P. Claffey
Kevin P. Claffey University of Connecticut Health Center
Kari Alitalo
Kari Alitalo University of Helsinki
Harold F. Dvorak
Harold F. Dvorak Beth Israel Deaconess Medical Center
Alistair R. R. Forrest
Alistair R. R. Forrest Harry Perkins Institute of Medical Research

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