World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
19865
World Ranking
11134
National Ranking
4821

Overview

Kevin P. Claffey is affiliated with the University of Connecticut Health Center in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a focus on specific subfields such as physiology, molecular biology, cancer research, biomedical engineering, and cell biology.

The scientist's work covers a diverse range of topics including syphilis diagnosis and treatment, nitric oxide and endothelin effects, angiogenesis and VEGF in cancer, mechanisms of cancer under hypoxia and metabolism, cellular mechanics and interactions, 3D printing applications in biomedical research, and reproductive tract infections research.

Kevin P. Claffey has contributed to several peer-reviewed publications. Notable recent papers include:

  • Development and utilization of Treponema pallidum expressing green fluorescent protein to study spirochete-host interactions and antibody-mediated clearance: expanding the toolbox for syphilis research, 2024, mBio
  • Electron microscopy imaging and mechanical characterization of T47D multicellular tumor spheroids-Older spheroids reduce interstitial space and become stiffer, 2023, PLoS ONE
  • PLCβ2 Promotes VEGF-Induced Vascular Permeability, 2022, Arteriosclerosis Thrombosis and Vascular Biology
  • Label-Free Morphological Phenotyping of In Vitro 3D Microtumors, 2022, Methods in molecular biology
  • GRK2 enforces androgen receptor dependence in the prostate and prostate tumors, 2020, Oncogene

The frequent co-authors who have collaborated with Claffey on multiple publications include Melissa J. Caimano, Kathryn N. Phoenix, Crystal F. Vicente, Christopher M. Hennelly, and Farhang Aghakhanian.

Claffey's research has been published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Arteriosclerosis Thrombosis and Vascular Biology, PLoS ONE, mBio, and Oncogene, reflecting multidisciplinary interests across biomedicine and molecular biology.

Best Publications

  • Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

    Mihaela Skobe;Thomas Hawighorst;David G. Jackson;Remko Prevo

  • Vascular Endothelial Cell Adherens Junction Assembly and Morphogenesis Induced by Sphingosine-1-Phosphate

    Menq-Jer Lee;Shobha Thangada;Kevin P Claffey;Nicolas Ancellin

  • Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis

    Michael Detmar;Lawrence F. Brown;Kevin P. Claffey;Kiang-Teck Yeo

  • Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin.

    D R Senger;S R Ledbetter;K P Claffey;A Papadopoulos-Sergiou

  • Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice.

    Michael Detmar;Lawrence F. Brown;Michael P. Schön;Brett M. Elicker

  • Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins.

    Donald R. Senger;Kevin P. Claffey;Julie E. Benes;Carole A. Perruzzi

  • Vascular permeability factor/vascular endothelial growth factor:A multifunctional angiogenic cytokine

    L. F. Brown;M. Detmar;K. Claffey;J. A. Nagy

  • Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis.

    K. P. Claffey;L. F. Brown;L. F. Del Aguila;K. Tognazzi

  • Vascular endothelial growth factor. Regulation by cell differentiation and activated second messenger pathways.

    K.P. Claffey;W.O. Wilkison;B.M. Spiegelman

  • Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability.

    Teresa Sanchez;Tatiana Estrada-Hernandez;Ji-Hye Paik;Miing-Tao Wu

  • Mast Cells Can Secrete Vascular Permeability Factor/ Vascular Endothelial Cell Growth Factor and Exhibit Enhanced Release after Immunoglobulin E–dependent Upregulation of Fcε Receptor I Expression

    Jürg Boesiger;Mindy Tsai;Marcus Maurer;Masao Yamaguchi

  • Vascular Permeability Factor/Vascular Endothelial Growth Factor: An Important Mediator of Angiogenesis in Malignancy and Inflammation

    Dvorak Hf;Detmar M;Claffey Kp;Nagy Ja

  • Hypoxia Regulates the Expression of Vascular Permeability Factor/Vascular Endothelial Growth Factor (VPF/VEGF) and its Receptors in Human Skin

    Michael Detmar;Lawrence F. Brown;Brygida Berse;Robert W. Jackman

  • TNF-α impairs insulin signaling and insulin stimulation of glucose uptake in C2C12muscle cells

    Luis F. del Aguila;Kevin P. Claffey;John P. Kirwan

  • Molecular imaging of VEGF receptors in angiogenic vasculature with single-chain VEGF-based probes.

    Marina V Backer;Zoya Levashova;Vimalkumar Patel;Brian T Jehning

  • Essential role of sphingosine 1–phosphate receptor 2 in pathological angiogenesis of the mouse retina

    Athanasia Skoura;Teresa Sanchez;Kevin Claffey;Suzanne M. Mandala

  • Selective inhibition of tumor microvascular permeability by cavtratin blocks tumor progression in mice

    Jean Philippe Gratton;Michelle I Lin;Jun Yu;Erik D Weiss

  • Regulation of VEGF/VPF expression in tumor cells : Consequences for tumor growth and metastasis

    Kevin P. Claffey;Gregory S. Robinson

  • Meningiomas: role of vascular endothelial growth factor/vascular permeability factor in angiogenesis and peritumoral edema.

    John Provias;Kevin Claffey;Leslie delAguila;Nelson Lau

  • Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis

    Michael Detmar;Lawrence F. Brown;Kevin P. Claffey;Kiang-Teck Yeo

Frequent Co-Authors

Michael Detmar
Michael Detmar ETH Zurich
Timothy Hla
Timothy Hla Harvard University
Lawrence F. Brown
Lawrence F. Brown Beth Israel Deaconess Medical Center
Harold F. Dvorak
Harold F. Dvorak Beth Israel Deaconess Medical Center
Jihye Paik
Jihye Paik Cornell University
Peter Brecher
Peter Brecher Boston University
Quing Zhu
Quing Zhu Washington University in St. Louis
Bruce M. Spiegelman
Bruce M. Spiegelman Harvard University
Jimmy K. Eng
Jimmy K. Eng University of Washington
Ann M. Dvorak
Ann M. Dvorak Beth Israel Deaconess Medical Center

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