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Medicine

D-Index
106
Citations
39074
World Ranking
6570
National Ranking
3491

Overview

Stephen B. Gruber is affiliated with the City Of Hope National Medical Center in the United States. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions within several subfields including Genetics, Oncology, Molecular Biology, Pathology and Forensic Medicine, and Cancer Research.

The major topics of their work include genetic factors in colorectal cancer, genetic associations and epidemiology, colorectal cancer screening and detection, BRCA gene mutations in cancer, cancer genomics and diagnostics, colorectal cancer treatments and studies, and cutaneous melanoma detection and management.

Among Stephen B. Gruber's recent publications are notable papers such as:

  • Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis, 2020, Nature Communications
  • The Prognostic Implications of Tumor Infiltrating Lymphocytes in Colorectal Cancer: A Systematic Review and Meta-Analysis, 2020, Scientific Reports
  • Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk, 2020, The American Journal of Human Genetics
  • Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study, 2023, Cancer Cell
  • Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study, 2020, BMC Medicine

They collaborate frequently with several coauthors, including Vı́ctor Moreno, Ulrike Peters, Marc J. Gunter, Gad Rennert, and Hermann Brenner, with collaborations ranging from around 57 to 70 joint works each.

Stephen B. Gruber's research output has been published in a variety of venues, with frequent contributions to:

  • UNC Libraries
  • Cancer Research
  • Cancer Epidemiology Biomarkers & Prevention
  • Journal of Clinical Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Microsatellite instability in colorectal cancer—the stable evidence

    Eduardo Vilar;Stephen B. Gruber

  • Frequency and Spectrum of Cancers in the Peutz-Jeghers Syndrome

    Nicholas Hearle;Valérie Schumacher;Fred H. Menko;Sylviane Olschwang

  • Statins and the Risk of Colorectal Cancer

    Jenny N. Poynter;Stephen B. Gruber;Peter D.R. Higgins;Ronit Almog

  • Statins and cancer prevention

    Marie-France Demierre;Peter D. R. Higgins;Stephen B. Gruber;Ernest Hawk

  • Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC

    Steven J. Laken;Gloria M. Petersen;Stephen B. Gruber;Carole Oddoux

  • Network modeling links breast cancer susceptibility and centrosome dysfunction.

    Miguel Angel Pujana;Jing Dong J Han;Lea M. Starita;Kristen N. Stevens

  • Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.

    Albert Tenesa;Susan M Farrington;James G D Prendergast;Mary E Porteous

  • Personalized Oncology Through Integrative High-Throughput Sequencing: A Pilot Study

    Sameek Roychowdhury;Matthew K. Iyer;Dan R. Robinson;Robert J. Lonigro

  • ASCO/SSO Review of Current Role of Risk-Reducing Surgery in Common Hereditary Cancer Syndromes

    José G. Guillem;William C. Wood;Jeffrey F. Moley;Andrew Berchuck

  • Risk of pancreatic cancer in families with Lynch syndrome.

    Fay Kastrinos;Fay Kastrinos;Bhramar Mukherjee;Nabihah Tayob;Fei Wang

  • Genetic/familial high-risk assessment: breast and ovarian.

    Mary B. Daly;Jennifer E. Axilbund;Saundra Buys;Beth Crawford

  • Discovery of common and rare genetic risk variants for colorectal cancer

    Jeroen R. Huyghe;Stephanie A. Bien;Tabitha A. Harrison;Hyun Min Kang

  • Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells.

    Eric J. Bernhard;Stephen B. Gruber;Ruth J. Muschel

  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    Catherine M Phelan;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Jonathan P Tyrer;Siddhartha P Kar

  • Prediction of Germline Mutations and Cancer Risk in the Lynch Syndrome

    Sining Chen;Wenyi Wang;Shing Lee;Khedoudja Nafa

  • Calculation of Risk of Colorectal and Endometrial Cancer Among Patients with Lynch Syndrome

    Elena Stoffel;Elena Stoffel;Bhramar Mukherjee;Victoria M. Raymond;Nabihah Tayob

  • Physical activity and risks of breast and colorectal cancer : a Mendelian randomisation analysis

    Nikos Papadimitriou;Niki Dimou;Konstantinos K. Tsilidis;Konstantinos K. Tsilidis;Barbara Banbury

  • Hereditary Colorectal Cancer Syndromes: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the Familial Risk–Colorectal Cancer: European Society for Medical Oncology Clinical Practice Guidelines

    Elena M. Stoffel;Pamela B. Mangu;Stephen B. Gruber;Stanley R. Hamilton

  • Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.

    Christophe Denoyelle;George Abou-Rjaily;Vladimir Bezrookove;Monique Verhaegen

  • Founder and Recurrent CDH1 mutations in families with Hereditary diffuse gastric Cancer. Editorial

    Pardeep Kaurah;Andrée Macmillan;Niki Boyd;Janine Senz

Frequent Co-Authors

Gad Rennert
Gad Rennert Technion – Israel Institute of Technology
Polly A. Newcomb
Polly A. Newcomb Fred Hutchinson Cancer Research Center
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Andrew T. Chan
Andrew T. Chan Harvard University
Graham G. Giles
Graham G. Giles University of Melbourne
Victor Moreno
Victor Moreno University of Barcelona
Kenneth Offit
Kenneth Offit Memorial Sloan Kettering Cancer Center
Martha L. Slattery
Martha L. Slattery University of Utah
Michael Hoffmeister
Michael Hoffmeister German Cancer Research Center
Daniel D. Buchanan
Daniel D. Buchanan University of Melbourne

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