World's Best Scientists 2026 revealed!

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Medicine

D-Index
153
Citations
80099
World Ranking
1050
National Ranking
602

Research.com Recognitions

  • 2016 - Member of the National Academy of Medicine (NAM)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Kenneth Offit is affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their research primarily focuses on the genetic basis of cancer, with particular emphasis on BRCA gene mutations and their role in cancer development.

The scientist's recent publications include:

  • Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants, 2020, JAMA Oncology
  • Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2, 2023, British Journal of Cancer
  • Clinical Utility of Genomic Sequencing for Hereditary Cancer Syndromes: An Observational Cohort Study, 2024, JCO Precision Oncology
  • The Scientific Foundation for Personal Genomics: Recommendations from a National Institutes of Health-Centers for Disease Control and Prevention Multidisciplinary Workshop, 2020, UNC Libraries

Frequent co-authors collaborating with Kenneth Offit include:

  • Miguel de la Hoya
  • Goska Leslie
  • Irene L. Andrulis
  • Maria A. Caligo
  • Wendy K. Chung

The venues where Offit's work has been published most often are:

  • JAMA Oncology
  • British Journal of Cancer
  • JCO Precision Oncology
  • UNC Libraries

The main fields of study associated with Offit's research are:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Research subfields include:

  • Genetics
  • Pathology and Forensic Medicine
  • Molecular Biology
  • Reproductive Medicine

The scientist's core topics of investigation cover:

  • BRCA gene mutations in cancer
  • Genetic factors in colorectal cancer
  • DNA Repair Mechanisms
  • Ovarian cancer diagnosis and treatment
  • Genomics and Rare Diseases

Kenneth Offit has been recognized by membership in professional organizations including:

  • Member of the National Academy of Medicine (NAM), 2016
  • Member of the Association of American Physicians

Best Publications

  • Risk-reducing salpingo-oophorectomy in women with a BRCA1 or BRCA2 mutation.

    Noah D. Kauff;Jaya M. Satagopan;Mark E. Robson;Lauren Scheuer

  • Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

    Colin C. Pritchard;Joaquin Mateo;Michael F. Walsh;Navonil De Sarkar

  • Recommendations for follow-up care of individuals with an inherited predisposition to Cancer. II. BRCA1 and BRCA2

    Wylie Burke;Mary Daly;Judy Garber;Jeffrey Botkin

  • The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds.

    S.V. Tavtigian;J. Simard;J. Rommens;F. Couch

  • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

    Nasim Mavaddat;Kyriaki Michailidou;Kyriaki Michailidou;Joe Dennis;Michael Lush

  • Integrative clinical genomics of metastatic cancer

    Dan R. Robinson;Yi Mi Wu;Robert J. Lonigro;Pankaj Vats

  • Genetic/familial high-risk assessment: Breast, ovarian, and pancreatic, version 2.2021

    Mary B. Daly;Tuya Pal;Michael P. Berry;Saundra S. Buys

  • Alterations of a Zinc Finger-Encoding Gene, BCL-6, in Diffuse Large-Cell Lymphoma

    B. H. Ye;F. Lista;F. Lo Coco;D. M. Knowles

  • Hereditary Cancer Predisposition Syndromes

    Judy E. Garber;Kenneth Offit

  • Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC

    Steven J. Laken;Gloria M. Petersen;Stephen B. Gruber;Carole Oddoux

  • Germline mutations in BAP1 predispose to melanocytic tumors

    Thomas Wiesner;Anna C Obenauf;Anna C Obenauf;Rajmohan Murali;Isabella Fried

  • Network modeling links breast cancer susceptibility and centrosome dysfunction.

    Miguel Angel Pujana;Jing Dong J Han;Lea M. Starita;Kristen N. Stevens

  • Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).

    Nasim Mavaddat;Daniel Barrowdale;Irene L. Andrulis;Susan M. Domchek

  • BCL-6 protein is expressed in germinal-center B cells

    Giorgio Cattoretti;Chih Chao Chang;Katarina Cechova;Jiandong Zhang

  • Risk-Reducing Salpingo-Oophorectomy for the Prevention of BRCA1- and BRCA2-Associated Breast and Gynecologic Cancer: A Multicenter, Prospective Study

    Noah D. Kauff;Susan M. Domchek;Tara M. Friebel;Mark E. Robson

  • Recommendations for Follow-up Care of Individuals With an Inherited Predisposition to Cancer: I. Hereditary Nonpolyposis Colon Cancer

    Wylie Burke;Gloria Petersen;Patrick M Lynch;Jeffrey Botkin

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

    Nasim Mavaddat;Paul D.P. Pharoah;Kyriaki Michailidou;Jonathan Tyrer

  • ASCO/SSO Review of Current Role of Risk-Reducing Surgery in Common Hereditary Cancer Syndromes

    José G. Guillem;William C. Wood;Jeffrey F. Moley;Andrew Berchuck

  • Genetic/familial high-risk assessment: breast and ovarian.

    Mary B. Daly;Jennifer E. Axilbund;Saundra Buys;Beth Crawford

Frequent Co-Authors

Mark E. Robson
Mark E. Robson Memorial Sloan Kettering Cancer Center
Graham G. Giles
Graham G. Giles University of Melbourne
Fergus J. Couch
Fergus J. Couch Mayo Clinic
Roger L. Milne
Roger L. Milne Cancer Council Victoria
Irene L. Andrulis
Irene L. Andrulis University of Toronto
Judy Garber
Judy Garber Harvard University
Katherine L. Nathanson
Katherine L. Nathanson University of Pennsylvania
Melissa C. Southey
Melissa C. Southey Monash University
Susan M. Domchek
Susan M. Domchek University of Pennsylvania
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center

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