World's Best Scientists 2026 revealed!
Irene L. Andrulis

Irene L. Andrulis

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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
120
Citations
56508
World Ranking
561
National Ranking
17

Medicine

D-Index
123
Citations
59655
World Ranking
3333
National Ranking
141

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award

Overview

Irene L. Andrulis is affiliated with the University of Toronto in Canada. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these fields, they have explored various subfields including Genetics, Oncology, Molecular Biology, Cancer Research, and Pulmonary and Respiratory Medicine.

The scientific topics addressed in their work include BRCA gene mutations in cancer, Genetic Associations and Epidemiology, Cancer Genomics and Diagnostics, Sarcoma Diagnosis and Treatment, Nutrition, Genetics, and Disease, Ovarian cancer diagnosis and treatment, and Cancer Risks and Factors.

Among their recent publications are the following papers:

  • Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses, 2020, Nature Genetics
  • Genetic insights into biological mechanisms governing human ovarian ageing, 2021, Nature
  • Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes, 2020, Nature Genetics
  • Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes, 2022, JAMA Oncology
  • Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants, 2020, Genetics in Medicine

Their frequent collaborators include Esther M. John, Manjeet K. Bolla, D. Gareth Evans, Joe Dennis, and Stig E. Bojesen.

Publication venues where they have contributed multiple papers include UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Breast Cancer Research, and Nature Communications.

Best Publications

  • Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

    Karoline B. Kuchenbaecker;Karoline B. Kuchenbaecker;John L. Hopper;Daniel R. Barnes;Kelly-Anne Phillips

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • Large-scale genotyping identifies 41 new loci associated with breast cancer risk

    Kyriaki Michailidou;Per Hall;Anna Gonzalez-Neira;Maya Ghoussaini

  • MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

    Kolja Eppert;Stephen W Scherer;Hilmi Ozcelik;Rosa Pirone

  • Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction.

    K. E. Noonan;C. Beck;T. A. Holzmayer;J. E. Chin

  • Breast-Cancer Risk in Families with Mutations in PALB2

    A. C. Antoniou;S. Casadei;T. Heikkinen;D. Barrowdale

  • RAD51B in Familial Breast Cancer

    Liisa M. Pelttari;Sofia Khan;Mikko Vuorela;Johanna I. Kiiski

  • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

    Nasim Mavaddat;Kyriaki Michailidou;Kyriaki Michailidou;Joe Dennis;Michael Lush

  • Associations of Breast Cancer Risk Factors With Tumor Subtypes: A Pooled Analysis From the Breast Cancer Association Consortium Studies

    Xiaohong R. Yang;Jenny Chang-Claude;Ellen L. Goode;Fergus J. Couch

  • Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women

    Leila Dorling;Sara Carvalho;Jamie Allen

  • Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).

    Nasim Mavaddat;Daniel Barrowdale;Irene L. Andrulis;Susan M. Domchek

  • HER2 and responsiveness of breast cancer to adjuvant chemotherapy.

    Kathleen I. Pritchard;Lois E. Shepherd;Frances P. O'Malley;Irene L. Andrulis

  • Association Between BRCA1 and BRCA2 Mutations and Survival in Women with Invasive Epithelial Ovarian Cancer

    Kelly L. Bolton;Kelly L. Bolton;Georgia Chenevix-Trench;Cindy Goh;Siegal Sadetzki

  • Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

    John R.B. Perry;Felix Day;Cathy E. Elks;Patrick Sulem

  • Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

    Kyriaki Michailidou;Jonathan Beesley;Sara Lindstrom;Sander Canisius

  • Detectable clonal mosaicism and its relationship to aging and cancer

    Kevin B. Jacobs;Kevin B. Jacobs;Meredith Yeager;Meredith Yeager;Weiyin Zhou;Weiyin Zhou;Sholom Wacholder

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

    Nasim Mavaddat;Paul D.P. Pharoah;Kyriaki Michailidou;Jonathan Tyrer

  • MicroRNA related polymorphisms and breast cancer risk

    Sofia Khan;Dario Greco;Dario Greco;Kyriaki Michailidou;Roger L. Milne;Roger L. Milne

  • neu/erbB-2 amplification identifies a poor-prognosis group of women with node-negative breast cancer. Toronto Breast Cancer Study Group.

    I L Andrulis;S B Bull;M E Blackstein;D Sutherland

Frequent Co-Authors

Graham G. Giles
Graham G. Giles University of Melbourne
Melissa C. Southey
Melissa C. Southey Monash University
Roger L. Milne
Roger L. Milne Cancer Council Victoria
Esther M. John
Esther M. John Stanford University
John L. Hopper
John L. Hopper University of Melbourne
Hiltrud Brauch
Hiltrud Brauch German Cancer Research Center
Julia A. Knight
Julia A. Knight Lunenfeld-Tanenbaum Research Institute
Douglas F. Easton
Douglas F. Easton University of Cambridge
Georgia Chenevix-Trench
Georgia Chenevix-Trench QIMR Berghofer Medical Research Institute
Fergus J. Couch
Fergus J. Couch Mayo Clinic

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