Cameron Brennan mainly focuses on Cancer research, Glioma, PTEN, Stem cell and Genetics. His Cancer research research is multidisciplinary, incorporating perspectives in Carcinogenesis, Loss of heterozygosity and Adenocarcinoma. His Glioma study incorporates themes from PI3K/AKT/mTOR pathway, Cell signaling, Signal transduction, Receptor tyrosine kinase and Epidermal growth factor receptor.
His research in Stem cell intersects with topics in Immunology and Cellular differentiation. His work in Gene and Mutation is related to Genetics. His specific area of interest is Gene, where Cameron Brennan studies DNA methylation.
His main research concerns Cancer research, Glioma, Cancer, Genetics and Internal medicine. His research integrates issues of Carcinogenesis, Immunology, Stem cell and PI3K/AKT/mTOR pathway, PTEN in his study of Cancer research. His Glioma research is multidisciplinary, relying on both Epidermal growth factor receptor, DNA methylation, Cancer cell, Pathology and Signal transduction.
His research investigates the connection with Cancer and areas like Brain tumor which intersect with concerns in Surgery. Genome, Gene, Genomics, Comparative genomic hybridization and Gene expression profiling are the core of his Genetics study. While the research belongs to areas of Gene expression profiling, Cameron Brennan spends his time largely on the problem of Bioinformatics, intersecting his research to questions surrounding Disease.
The scientist’s investigation covers issues in Cancer research, Cancer, Radiology, Glioblastoma and Oncology. His Cancer research study combines topics from a wide range of disciplines, such as Methylation, DNA methylation, Brain tumor, Stem cell and Epigenetics. As a member of one scientific family, Cameron Brennan mostly works in the field of DNA methylation, focusing on Glioma and, on occasion, Carcinogenesis, Pathology, Liquid biopsy, Lumbar puncture and Genotyping.
His Cancer research integrates issues from Lung cancer and Renal cell carcinoma. His Glioblastoma research is multidisciplinary, incorporating elements of DNA microarray, Lineage, Computational biology and Human genetics. His Gene research is multidisciplinary, relying on both Molecular biology and Clear cell renal cell carcinoma.
Cameron Brennan spends much of his time researching Cancer research, Brain tumor, Glioblastoma, Glioma and Immune system. His research integrates issues of Cell culture, Chemotherapy, Genetically Engineered Mouse, Regulation of gene expression and Neural stem cell in his study of Cancer research. The study incorporates disciplines such as Immunohistochemistry, Ex vivo, Dasatinib and Central nervous system in addition to Brain tumor.
The Glioblastoma study combines topics in areas such as Cell of origin, Lineage, ERBB3 and Cell lineage. Cameron Brennan interconnects Somatic cell, Phenotype, Mutation, Germline and DNA repair in the investigation of issues within Glioma. His work focuses on many connections between Cancer and other disciplines, such as Histology, that overlap with his field of interest in Oncology.
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Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
Roel G. W. Verhaak;Katherine A. Hoadley;Elizabeth Purdom;Victoria Wang.
Cancer Cell (2010)
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir.
Nature (2008)
Integrated genomic analyses of ovarian carcinoma
D. Bell;A. Berchuck;M. Birrer;J. Chien.
Nature (2011)
The Somatic Genomic Landscape of Glioblastoma
Cameron W. Brennan;Roel G W Verhaak;Aaron McKenna;Benito Campos.
Cell (2013)
Malignant astrocytic glioma: genetics, biology, and paths to treatment.
Frank B. Furnari;Tim Fenton;Robert M. Bachoo;Akitake Mukasa.
Genes & Development (2007)
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.
Daniel J. Brat;Roel G.W. Verhaak;Kenneth D. Aldape;W. K.Alfred Yung.
The New England Journal of Medicine (2015)
Tumor mutational load predicts survival after immunotherapy across multiple cancer types.
Robert M Samstein;Chung-Han Lee;Chung-Han Lee;Alexander N Shoushtari;Alexander N Shoushtari;Matthew D Hellmann;Matthew D Hellmann.
Nature Genetics (2019)
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
James Bean;Cameron Brennan;Jin-Yuan Shih;Gregory Riely.
Proceedings of the National Academy of Sciences of the United States of America (2007)
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
Stephanie M Pyonteck;Leila Akkari;Alberto J Schuhmacher;Robert L Bowman.
Nature Medicine (2013)
Molecular characterization of the tumor microenvironment in breast cancer
Minna Allinen;Rameen Beroukhim;Li Cai;Cameron Brennan.
Cancer Cell (2004)
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