D-Index & Metrics Best Publications
Research.com 2022 Best Scientist Award Badge
Molecular Biology
USA
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Best Scientists D-index 174 Citations 129,950 537 World Ranking 528 National Ranking 353
Medicine D-index 172 Citations 129,599 515 World Ranking 273 National Ranking 179
Molecular Biology D-index 169 Citations 121,679 467 World Ranking 22 National Ranking 18

Research.com Recognitions

Awards & Achievements

2023 - Research.com Molecular Biology in United States Leader Award

2022 - Research.com Best Scientist Award

2014 - Fellow of the American Association for the Advancement of Science (AAAS)

2012 - Member of the National Academy of Sciences

2010 - Fellow of the American Academy of Arts and Sciences

2009 - Szent-Györgyi Prize for Progress in Cancer Research, National Foundation for Cancer Research (NFCR)

2004 - Member of the National Academy of Medicine (NAM)

Member of the Association of American Physicians

Lisbon Academy of Sciences (Academia das Ciências de Lisboa)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

Ronald A. DePinho mostly deals with Cancer research, Cell biology, Genetics, Telomere and Telomerase. His Cancer research study combines topics in areas such as Cellular differentiation, Pancreatic cancer, Carcinogenesis, Tumor suppressor gene and PTEN. His work on Apoptosis expands to the thematically related Cell biology.

His Telomere study incorporates themes from Senescence, Genome instability and Function. The various areas that Ronald A. DePinho examines in his Telomerase study include Cancer cell and Immunology. In his research, Gene expression and Transcription factor is intimately related to Molecular biology, which falls under the overarching field of Telomerase reverse transcriptase.

His most cited work include:

  • Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA (1829 citations)
  • Malignant astrocytic glioma: genetics, biology, and paths to treatment (1780 citations)
  • International network of cancer genome projects (1611 citations)

What are the main themes of his work throughout his whole career to date?

Ronald A. DePinho mainly investigates Cancer research, Cell biology, Cancer, Genetics and Molecular biology. His study looks at the intersection of Cancer research and topics like PTEN with Prostate cancer. Ronald A. DePinho interconnects Telomere, Cellular differentiation, Transcription factor and Telomerase in the investigation of issues within Cell biology.

His work investigates the relationship between Telomere and topics such as DNA damage that intersect with problems in DNA repair. His studies in Cancer integrate themes in fields like Oncology and Bioinformatics. His research in Gene and Genome are components of Genetics.

He most often published in these fields:

  • Cancer research (42.15%)
  • Cell biology (24.45%)
  • Cancer (18.98%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cancer research (42.15%)
  • Cancer (18.98%)
  • KRAS (6.20%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cancer research, Cancer, KRAS, Pancreatic cancer and Cancer cell. His Cancer research study combines topics from a wide range of disciplines, such as Tumor progression, Prostate cancer and PTEN. His Cancer study integrates concerns from other disciplines, such as PI3K/AKT/mTOR pathway, MEDLINE and In vivo.

His Pancreatic cancer research is multidisciplinary, incorporating elements of Syndecan 1, Epigenetics and Bioinformatics. Telomere is closely connected to Disease in his research, which is encompassed under the umbrella topic of Bioinformatics. Stem cell is a subfield of Cell biology that he studies.

Between 2013 and 2021, his most popular works were:

  • Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function (637 citations)
  • Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment (549 citations)
  • Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer (386 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

Ronald A. DePinho mainly focuses on Cancer research, KRAS, Pancreatic cancer, Glioma and Transcription factor. His Cancer research research includes themes of Cancer cell, Immunology, YAP1, Tumor progression and PTEN. His study looks at the relationship between KRAS and topics such as Signal transduction, which overlap with Cell growth and Pharmacology.

His biological study spans a wide range of topics, including Mitochondrion and Bioinformatics. His studies deal with areas such as Autophagy, Molecular biology and Cell biology as well as Transcription factor. His Cell biology research is multidisciplinary, relying on both Genome instability, Splicing factor, RNA splicing, Messenger RNA and Regulator.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Malignant astrocytic glioma: genetics, biology, and paths to treatment.

Frank B. Furnari;Tim Fenton;Robert M. Bachoo;Akitake Mukasa.
Genes & Development (2007)

2676 Citations

Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA

María A. Blasco;María A. Blasco;Han Woong Lee;M. Prakash Hande;Enrique Samper.
Cell (1997)

2563 Citations

ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

Teri G. Boulton;Steven H. Nye;David J. Robbins;Nancy Y. Ip.
Cell (1991)

2432 Citations

Hepatocellular carcinoma pathogenesis: from genes to environment

Paraskevi A. Farazi;Paraskevi A. Farazi;Ronald A. DePinho.
Nature Reviews Cancer (2006)

2253 Citations

The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin

Reuben J. Shaw;Reuben J. Shaw;Katja A. Lamia;Debbie Vasquez;Seung Hoi Koo;Seung Hoi Koo.
Science (2005)

2173 Citations

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

Reuben J. Shaw;Monica Kosmatka;Nabeel Bardeesy;Rebecca L. Hurley.
Proceedings of the National Academy of Sciences of the United States of America (2004)

1974 Citations

The Ink4a Tumor Suppressor Gene Product, p19Arf, Interacts with MDM2 and Neutralizes MDM2's Inhibition of p53

Jason Pomerantz;Nicole Schreiber-Agus;Nanette J. Liégeois;Adam Silverman.
Cell (1998)

1954 Citations

Role of the INK4a locus in tumor suppression and cell mortality

Manuel Serrano;Han Woong Lee;Lynda Chin;Carlos Cordon-Cardo.
Cell (1996)

1909 Citations

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

Jacqueline J. L. Jacobs;Karin Kieboom;Silvia Marino;Ronald A DePinho.
Nature (1999)

1892 Citations

International network of cancer genome projects

Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker.
(2010)

1839 Citations

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