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D-Index & Metrics

Medicine

D-Index
113
Citations
58185
World Ranking
4871
National Ranking
2639

Overview

Nabeel Bardeesy is affiliated with Harvard University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a significant focus on Medicine. The main subfields of their work include Molecular Biology, Oncology, Cancer Research, Surgery, and Pulmonary and Respiratory Medicine.

The scientist's research covers several key topics:

  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Pancreatic and Hepatic Oncology Research
  • RNA modifications and cancer
  • Fibroblast Growth Factor Research
  • Peptidase Inhibition and Analysis
  • Epigenetics and DNA Methylation
  • Cancer Genomics and Diagnostics

Nabeel Bardeesy has contributed to numerous scientific publications, many of which appear in high-profile venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Cancer Research
  • Cancer Discovery
  • Nature Communications

Recent notable papers include:

  • "Immunology and immunotherapy of cholangiocarcinoma," 2023, Nature Reviews Gastroenterology & Hepatology
  • "ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1-mutant lung cancer," 2021, Nature Cancer
  • "Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway," 2023, Cell
  • "The clinical landscape of cell-free DNA alterations in 1671 patients with advanced biliary tract cancer," 2022, Annals of Oncology
  • "Therapeutically reprogrammed nutrient signalling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer," 2021, Nature Nanotechnology

The scientist collaborates frequently with other researchers, including:

  • Lei Shi
  • Kwok-Kin Wong
  • Vikram Deshpande
  • Meng-Ju Wu
  • Vindhya Vijay

Best Publications

  • The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin

    Reuben J. Shaw;Reuben J. Shaw;Katja A. Lamia;Debbie Vasquez;Seung Hoi Koo;Seung Hoi Koo

  • The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

    Reuben J. Shaw;Monica Kosmatka;Nabeel Bardeesy;Rebecca L. Hurley

  • Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

    Benjamin J. Raphael;Ralph H. Hruban;Andrew J. Aguirre;Richard A. Moffitt

  • Glutamine supports pancreatic cancer growth through a Kras-regulated metabolic pathway

    Jaekyoung Son;Costas A. Lyssiotis;Costas A. Lyssiotis;Haoqiang Ying;Xiaoxu Wang

  • Pancreatic cancers require autophagy for tumor growth

    Shenghong Yang;Xiaoxu Wang;Gianmarco Contino;Marc Liesa

  • Pancreatic cancer biology and genetics

    Nabeel Bardeesy;Ronald A. DePinho

  • The LKB1 tumor suppressor negatively regulates mTOR signaling

    Reuben J Shaw;Nabeel Bardeesy;Brendan D Manning;Lyle Lopez

  • LKB1 modulates lung cancer differentiation and metastasis

    Hongbin Ji;Matthew R. Ramsey;D. Neil Hayes;Cheng Fan

  • Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma.

    Andrew J. Aguirre;Nabeel Bardeesy;Manisha Sinha;Lyle Lopez

  • Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis.

    Norman E. Sharpless;Nabeel Bardeesy;Kee Ho Lee;Daniel Carrasco

  • Essential role for oncogenic Ras in tumour maintenance

    Lynda Chin;Alice Tam;Alice Tam;Jason Pomerantz;Michelle Wong

  • Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

    Dawang Zhou;Claudius Conrad;Fan Xia;Ji Sun Park

  • Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner

    Adem Kalender;Anand Selvaraj;Anand Selvaraj;So Young Kim;So Young Kim;Pawan Gulati

  • A gene expression signature associated with “K-Ras addiction” reveals regulators of EMT and tumor cell survival

    Anurag Singh;Patricia Greninger;Daniel Rhodes;Louise Koopman

  • Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

    Triantafyllos Stylianopoulos;John D. Martin;John D. Martin;Vikash P. Chauhan;Saloni R. Jain;Saloni R. Jain

  • Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer

    Nabeel Bardeesy;Kuang Hung Cheng;Justin H. Berger;Gerald C. Chu

  • Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.

    Rushika M. Perera;Svetlana Stoykova;Brandon N. Nicolay;Kenneth N. Ross

  • Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.

    Nabeel Bardeesy;Andrew J. Aguirre;Gerald C. Chu;Kuang Hung Cheng

  • Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome.

    Michael N. Corradetti;Ken Inoki;Nabeel Bardeesy;Ronald A. DePinho

  • TGF-β Tumor Suppression Through A Lethal EMT

    Charles J. David;Yun Han Huang;Mo Chen;Jie Su

Frequent Co-Authors

Vikram Deshpande
Vikram Deshpande Harvard University
Ronald A. DePinho
Ronald A. DePinho The University of Texas MD Anderson Cancer Center
Kwok-Kin Wong
Kwok-Kin Wong New York University
Andrew X. Zhu
Andrew X. Zhu Harvard University
Cristina R. Ferrone
Cristina R. Ferrone Harvard University
Sridhar Ramaswamy
Sridhar Ramaswamy Harvard University
Norman E. Sharpless
Norman E. Sharpless National Institutes of Health
David T. Ting
David T. Ting Harvard University
Yujin Hoshida
Yujin Hoshida The University of Texas Southwestern Medical Center
Lynda Chin
Lynda Chin The University of Texas Health Science Center at Houston

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