Jennifer P. Morton

Overview

Best Publications

• Genomic analyses identify molecular subtypes of pancreatic cancer

  Bailey P;Chang Dk;Nones K;Nones K;Johns Al

  3672
  Citations

• A complex secretory program orchestrated by the inflammasome controls paracrine senescence

  Juan Carlos Acosta;Ana Banito;Torsten Wuestefeld;Athena Georgilis

  1944
  Citations

• The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

  Ulrich Wellner;Jörg Schubert;Ulrike C Burk;Otto Schmalhofer

  1939
  Citations

• CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma

  Colin W. Steele;Saadia A. Karim;Joshua D.G. Leach;Peter Bailey

  756
  Citations

• p53 status determines the role of autophagy in pancreatic tumour development

  Mathias T. Rosenfeldt;Jim O’Prey;Jennifer P. Morton;Colin Nixon

  743
  Citations

• Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

  Jennifer P. Morton;Paul Timpson;Saadia A. Karim;Rachel A. Ridgway

  706
  Citations

• The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration

  Birgit Ritschka;Mekayla Storer;Alba Mas;Florian Heinzmann

  567
  Citations

• Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles

  Susanne Walz;Francesca Lorenzin;Jennifer Morton;Katrin E. Wiese

  524
  Citations

• Matrix stiffness induces epithelial-mesenchymal transition and promotes chemoresistance in pancreatic cancer cells.

  A J Rice;E Cortes;D Lachowski;B C H Cheung

  460
  Citations

• Rab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progression

  Marta A. Dozynkiewicz;Nigel B. Jamieson;Nigel B. Jamieson;Iain MacPherson;Joan Grindlay

  356
  Citations

• Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer.

  Christopher J. Halbrook;Corbin Pontious;Ilya Kovalenko;Laura Lapienyte

  339
  Citations

• Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis

  Jennifer P. Morton;Michelle E. Mongeau;David S. Klimstra;John P. Morris

  284
  Citations

• Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis

  Claire Vennin;Claire Vennin;Venessa T. Chin;Venessa T. Chin;Sean C. Warren;Sean C. Warren;Morghan C. Lucas;Morghan C. Lucas

  266
  Citations

• Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy.

  Bryan W Miller;Jennifer P Morton;Mark Pinese;Grazia Saturno

  265
  Citations

• A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression

  Francesca R. Auciello;Vinay Bulusu;Chet Oon;Jacqueline Tait-Mulder

  253
  Citations

• MicroRNA Molecular Profiles Associated with Diagnosis, Clinicopathologic Criteria, and Overall Survival in Patients with Resectable Pancreatic Ductal Adenocarcinoma

  Nigel B. Jamieson;Douglas C. Morran;Jennifer P. Morton;Asif Ali

  247
  Citations

• CAF Subpopulations: A New Reservoir of Stromal Targets in Pancreatic Cancer.

  Brooke A. Pereira;Claire Vennin;Michael Papanicolaou;Cecilia R. Chambers;Cecilia R. Chambers

  242
  Citations

• Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis.

  Alyssa L. Kennedy;Jennifer P. Morton;Indrani Manoharan;David M. Nelson

  235
  Citations

• Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity

  Colin Hutton;Felix Heider;Adrian Blanco-Gomez;Antonia Banyard

  225
  Citations

• CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

  Claire Vennin;Claire Vennin;Claire Vennin;Pauline Mélénec;Pauline Mélénec;Romain Rouet;Romain Rouet;Max Nobis;Max Nobis

  220
  Citations