World's Best Scientists 2026 revealed!
Award Badge
Genetics
USA
2026
Award Badge
Genetics and Molecular Biology
USA
2024

D-Index & Metrics

Genetics

D-Index
160
Citations
133487
World Ranking
96
National Ranking
47

Medicine

D-Index
161
Citations
134820
World Ranking
735
National Ranking
418

Research.com Recognitions

  • 2026 - Research.com Genetics in United States Leader Award
  • 2025 - Research.com Genetics in United States Leader Award
  • 2024 - Research.com Genetics in United States Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United States Leader Award
  • 2023 - Research.com Genetics in United States Leader Award
  • 2019 - Member of the National Academy of Medicine (NAM)
  • 2017 - Member of the National Academy of Sciences
  • 2013 - Fellow of the American Academy of Arts and Sciences
  • 2006 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2005 - Paul Marks Prize for Cancer Research, Memorial Sloan Kettering Cancer Center

Overview

Scott W. Lowe is affiliated with the Memorial Sloan Kettering Cancer Center in the United States. Their research spans multiple fields within biochemistry, genetics, molecular biology, and medicine, with specific focus on subfields such as molecular biology, oncology, immunology, cancer research, and hematology.

The scientist's primary research topics include:

  • Pancreatic and Hepatic Oncology Research
  • Epigenetics and DNA Methylation
  • Cancer Genomics and Diagnostics
  • Immune Cells in Cancer
  • Cancer Cells and Metastasis
  • CRISPR and Genetic Engineering
  • Cancer Immunotherapy and Biomarkers

Recent significant papers authored by Scott W. Lowe include the following:

  • Senolytic CAR T cells reverse senescence-associated pathologies, 2020, Nature
  • Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks, 2020, Cell
  • Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer, 2020, Cell
  • Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy, 2021, JNCI Journal of the National Cancer Institute
  • A gene-environment-induced epigenetic program initiates tumorigenesis, 2021, Nature

The scientist frequently collaborates with a core group of co-authors, including Yu-Jui Ho, Timour Baslan, Francisco J. Sánchez-Rivera, Elisa de Stanchina, and Sha Tian.

Scott W. Lowe's work is regularly published in several scientific venues with notable frequency. These venues include:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Discovery
  • Nature
  • Nature Cancer

Awards received by Scott W. Lowe include:

  • Member of the National Academy of Medicine (NAM), 2019
  • Member of the National Academy of Sciences, 2017
  • Fellow of the American Academy of Arts and Sciences, 2013
  • Fellow of the American Association for the Advancement of Science (AAAS), 2006
  • Paul Marks Prize for Cancer Research, Memorial Sloan Kettering Cancer Center, 2005

Best Publications

  • Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

    Manuel Serrano;Athena W Lin;Mila E McCurrach;David Beach;David Beach

  • A microRNA polycistron as a potential human oncogene

    Lin Xiang He;J. Michael Thomson;Michael T Hemann;Eva Hernando-Monge

  • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

    S W Lowe;H E Ruley;T Jacks;D E Housman

  • p53 is required for radiation-induced apoptosis in mouse thymocytes

    Scott W. Lowe;Earlene M. Schmitt;Sallie W. Smith;Barbara A. Osborne

  • A microRNA component of the p53 tumour suppressor network

    Lin He;Xingyue He;Xingyue He;Lee P. Lim;Elisa de Stanchina;Elisa de Stanchina

  • Apoptosis: a link between cancer genetics and chemotherapy.

    Ricky W. Johnstone;Astrid A. Ruefli;Scott W. Lowe

  • Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

    Thomas G. Graeber;Cynthia Osmanian;Tyler Jacks;David E. Housman

  • Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

    Wen Xue;Lars Zender;Cornelius Miething;Ross A. Dickins;Ross A. Dickins

  • APOPTOSIS IN CANCER

    Scott W. Lowe;Athena W. Lin

  • Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence.

    Masashi Narita;Sabrina Nuñez;Sabrina Nuñez;Edith Heard;Masako Narita

  • RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

    Johannes Zuber;Junwei Shi;Junwei Shi;Eric Wang;Amy R. Rappaport;Amy R. Rappaport

  • p53 status and the efficacy of cancer therapy in vivo

    SW Lowe;S Bodis;A McClatchey;L Remington

  • Senescence of activated stellate cells limits liver fibrosis

    Valery Krizhanovsky;Monica Yon;Monica Yon;Ross A. Dickins;Stephen Hearn

  • Control of apoptosis by p53.

    Jordan S Fridman;Scott W Lowe

  • Intrinsic tumour suppression

    Scott W. Lowe;Enrique Cepero;Gerard Evan

  • Putting p53 in Context

    Edward R. Kastenhuber;Scott W. Lowe;Scott W. Lowe

  • Differential requirement for caspase 9 in apoptotic pathways in vivo

    Razqallah Hakem;Razqallah Hakem;Anne Hakem;Anne Hakem;Gordon S Duncan;Gordon S Duncan;Jeffrey T Henderson

  • Reversal of human cellular senescence: roles of the p53 and p16 pathways

    Christian M. Beauséjour;Ana Krtolica;Francesco Galimi;Francesco Galimi;Masashi Narita

  • p53-Dependent apoptosis suppresses tumor growth and progression in vivo

    Holly Symonds;Leonard Krall;Lee Remington;Mayte Saenz-Robles

  • The microcosmos of cancer

    Amaia Lujambio;Scott W. Lowe;Scott W. Lowe

Frequent Co-Authors

Johannes Zuber
Johannes Zuber Research Institute of Molecular Pathology
Gregory J. Hannon
Gregory J. Hannon University of Cambridge
Lars Zender
Lars Zender German Cancer Research Center
Wen Xue
Wen Xue University of Massachusetts Chan Medical School
Ricky W. Johnstone
Ricky W. Johnstone Peter MacCallum Cancer Centre
Scott C. Kogan
Scott C. Kogan University of California, San Francisco
Carlos Cordon-Cardo
Carlos Cordon-Cardo Icahn School of Medicine at Mount Sinai
Jerry Pelletier
Jerry Pelletier McGill University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring genetics opens doors to many dynamic career paths and flexible online study options. For those interested in healthcare administration, online medical coding programs are a popular choice, offering vital skills for medical records and billing positions.

Students seeking to accelerate their education should consider fast track bachelor degree options—these can help you earn your degree efficiently and enter the workforce sooner.

For maximum flexibility, many universities now offer online self paced college courses, enabling you to learn at your own tempo—ideal for balancing studies with work or family commitments.

Additionally, applying for online programs is simpler than ever, with several online universities with no application fee available, making it cost-effective to explore multiple programs before committing.

Whether you’re focused on genetics or a related field, these online pathways can help you build a rewarding career and achieve your academic goals on your terms.

Best Scientists Citing Scott W. Lowe

Trending Scientists

Recently Published Articles