2022 - Research.com Best Scientist Award
2022 - Research.com Genetics and Molecular Biology in Canada Leader Award
2019 - Member of Academia Europaea
2005 - Fellow of the American Academy of Arts and Sciences
2002 - Member of the National Academy of Sciences
1994 - Fellow of the Royal Society, United Kingdom
1986 - Fellow of the Royal Society of Canada Academy of Science
Tak W. Mak mostly deals with Cell biology, Molecular biology, Immunology, Cancer research and Cytotoxic T cell. His Cell biology research is multidisciplinary, incorporating perspectives in Apoptosis, Transcription factor and Caspase 8. His Molecular biology study incorporates themes from T cell, Thymocyte, T-cell receptor and Transcription, Gene.
His research in Immunology intersects with topics in Receptor and Cellular differentiation. Tak W. Mak works mostly in the field of Cancer research, limiting it down to concerns involving PTEN and, occasionally, Protein kinase B. His research in Cytotoxic T cell tackles topics such as CD8 which are related to areas like Major histocompatibility complex.
Tak W. Mak focuses on Cell biology, Immunology, Molecular biology, Cancer research and T cell. The concepts of his Cell biology study are interwoven with issues in Apoptosis, Programmed cell death, Cellular differentiation and Transcription factor. The study of Immunology is intertwined with the study of Receptor in a number of ways.
His studies in Molecular biology integrate themes in fields like T lymphocyte, Thymocyte, CD8, Gene and T-cell receptor. His Cancer research research integrates issues from Carcinogenesis, Cancer, Tumor suppressor gene, Kinase and PTEN. Many of his studies involve connections with topics such as Cytotoxic T cell and T cell.
The scientist’s investigation covers issues in Cancer research, Cell biology, Immune system, Immunology and Cancer. His studies deal with areas such as Carcinogenesis, Cell, Mitosis and Cancer cell as well as Cancer research. As a member of one scientific family, Tak W. Mak mostly works in the field of Cell biology, focusing on Downregulation and upregulation and, on occasion, Cell growth.
His Immune system study combines topics in areas such as Blockade, Disease and Neuroscience. His work carried out in the field of Immunology brings together such families of science as Receptor and Programmed cell death. Tak W. Mak combines subjects such as Tumor necrosis factor alpha and Autoimmunity with his study of Inflammation.
Tak W. Mak spends much of his time researching Cancer research, Immunology, Immune system, Cell biology and Receptor. Tak W. Mak has researched Cancer research in several fields, including Mitosis, Genome instability, Proinflammatory cytokine, STAT3 and Triple-negative breast cancer. Tak W. Mak has researched Immunology in several fields, including Endocrinology, Internal medicine and Lipocalin.
His Immune system study frequently draws connections between related disciplines such as Cytotoxic T cell. A large part of his Cell biology studies is devoted to Hippo signaling. The study incorporates disciplines such as Tumor microenvironment, Downregulation and upregulation and Signal transduction in addition to Receptor.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
Young-Yun Kong;Hiroki Yoshida;Ildiko Sarosi;Hong-Lin Tan.
Nature (1999)
Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4
Takeshi Takahashi;Tomoyuki Tagami;Sayuri Yamazaki;Toshimitsu Uede.
Journal of Experimental Medicine (2000)
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts.
Hiroshi Takayanagi;Hiroshi Takayanagi;Sunhwa Kim;Takako Koga;Takako Koga;Hiroshi Nishina.
Developmental Cell (2002)
Tumor necrosis factor-α is required in the protective immune response against mycobacterium tuberculosis in mice
Jo Anne L. Flynn;Marsha M. Goldstein;John Chan;Karla J. Triebold.
Immunity (1995)
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection.
Klaus Pfeffer;Toshifumi Matsuyama;Thomas M. Kündig;Andrew Wakeham.
Cell (1993)
BCL-2, BCL-XL Sequester BH3 Domain-Only Molecules Preventing BAX- and BAK-Mediated Mitochondrial Apoptosis
Emily H.-Y.A Cheng;Michael C Wei;Solly Weiler;Richard A Flavell.
Molecular Cell (2001)
Caspase Functions in Cell Death and Disease
David R. McIlwain;Thorsten Berger;Tak W. Mak.
Cold Spring Harbor Perspectives in Biology (2013)
Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis.
Megan Cully;Megan Cully;Han You;Arnold J. Levine;Tak W. Mak.
Nature Reviews Cancer (2006)
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid.
Mathias Chamaillard;Masahito Hashimoto;Yasuo Horie;Junya Masumoto.
Nature Immunology (2003)
Pathways of apoptotic and non-apoptotic death in tumour cells.
Hitoshi Okada;Tak W. Mak.
Nature Reviews Cancer (2004)
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