World's Best Scientists 2026 revealed!
Hideo Yagita

Hideo Yagita

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Immunology
Japan
2026
Award Badge
Medicine
Japan
2026

D-Index & Metrics

Best Scientists

D-Index
165
Citations
100915
World Ranking
1044
National Ranking
17

Immunology

D-Index
166
Citations
103086
World Ranking
62
National Ranking
4

Medicine

D-Index
166
Citations
103617
World Ranking
608
National Ranking
8

Hideo Yagita publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Hideo Yagita sits on this spectrum.

62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 68 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientists 807+ publications: 100 scientists
62 publications 807+

This scientist: 1,064 publications — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

Hideo Yagita D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Hideo Yagita sits on this spectrum.

40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 162 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40 D-Index 157+

This scientist: 166 D-Index — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Immunology in Japan Leader Award
  • 2026 - Research.com Medicine in Japan Leader Award
  • 2025 - Research.com Immunology in Japan Leader Award
  • 2025 - Research.com Medicine in Japan Leader Award
  • 2023 - Research.com Immunology in Japan Leader Award
  • 2023 - Research.com Medicine in Japan Leader Award
  • 2022 - Research.com Immunology in Japan Leader Award
  • 2022 - Research.com Medicine in Japan Leader Award

Overview

Hideo Yagita is affiliated with Juntendo University in Japan, where their research primarily spans the fields of immunology and microbiology, medicine, and biochemistry, genetics, and molecular biology. Their subfields of study include immunology, molecular biology, oncology, physiology, and biomedical engineering.

Their research topics focus extensively on immune cell function and interaction, immunotherapy and immune responses, cancer immunotherapy and biomarkers, CAR-T cell therapy research, T-cell and B-cell immunology, fibroblast growth factor research, and the role of immune cells in cancer.

Hideo Yagita has contributed multiple papers in notable scientific journals. Some of the recent publications include:

  • The allergy mediator histamine confers resistance to immunotherapy in cancer patients via activation of the macrophage histamine receptor H1 (2021, Cancer Cell)
  • PLGA-particle vaccine carrying TLR3/RIG-I ligand Riboxxim synergizes with immune checkpoint blockade for effective anti-cancer immunotherapy (2021, Nature Communications)
  • Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer (2021, Nature Communications)
  • CD39+PD-1+CD8+ T cells mediate metastatic dormancy in breast cancer (2021, Nature Communications)
  • Muscle weakness and selective muscle atrophy in osteoprotegerin-deficient mice (2020, Human Molecular Genetics)

Their frequent co-authors include:

  • Hiroyasu Nakano
  • Takashi Nishina
  • Tetuo Mikami
  • Soh Yamazaki
  • Yuichi Tsuchiya

Hideo Yagita's research has been published in a variety of scientific venues, with multiple publications in:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal for ImmunoTherapy of Cancer
  • iScience
  • Journal of Allergy and Clinical Immunology

Best Publications

  • Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes

    Yasutoshi Agata;Akemi Kawasaki;Hiroyuki Nishimura;Yasumasa Ishida

  • PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors

    Michael A. Curran;Welby Montalvo;Hideo Yagita;James P. Allison

  • Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma.

    Tyler R. Simpson;Fubin Li;Welby Montalvo-Ortiz;Manuel A. Sepulveda

  • Expression of Programmed Death 1 Ligands by Murine T Cells and APC

    Tomohide Yamazaki;Hisaya Akiba;Hideyuki Iwai;Hironori Matsuda

  • Clinical Significance and Therapeutic Potential of the Programmed Death-1 Ligand/Programmed Death-1 Pathway in Human Pancreatic Cancer

    Takeo Nomi;Masayuki Sho;Takahiro Akahori;Kaoru Hamada

  • Clinical Significance of Programmed Death-1 Ligand-1 and Programmed Death-1 Ligand-2 Expression in Human Esophageal Cancer

    Yuichiro Ohigashi;Masayuki Sho;Yukishige Yamada;Yoshikazu Tsurui

  • VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors.

    Thibault Voron;Orianne Colussi;Elie Marcheteau;Simon Pernot

  • ATP drives lamina propria T H 17 cell differentiation

    Koji Atarashi;Junichi Nishimura;Tatsuichiro Shima;Yoshinori Umesaki

  • New aspects of natural-killer-cell surveillance and therapy of cancer

    Mark J. Smyth;Yoshihiro Hayakawa;Kazuyoshi Takeda;Hideo Yagita

  • The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice.

    Mohammed Javeed I. Ansari;Alan D. Salama;Alan D. Salama;Tanuja Chitnis;Tanuja Chitnis;R. Neal Smith

  • Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts

    Sergio A. Quezada;Tyler R. Simpson;Karl S. Peggs;Taha Merghoub

  • Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

    Madhav D. Sharma;Babak Baban;Phillip Chandler;De Yan Hou

  • Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells.

    Kazuyoshi Takeda;Yoshihiro Hayakawa;Mark J. Smyth;Nobuhiko Kayagaki

  • Activation of NK cell cytotoxicity.

    Mark J. Smyth;Erika Cretney;Janice M. Kelly;Jennifer A. Westwood

  • Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

    Shigeki Chiba;Muhammad Baghdadi;Hisaya Akiba;Hironori Yoshiyama

  • Inhibition of NF-κB in cancer cells converts inflammation- induced tumor growth mediated by TNFα to TRAIL-mediated tumor regression

    Jun-Li Luo;Shin Maeda;Li-Chung Hsu;Hideo Yagita

  • Increased Susceptibility to Tumor Initiation and Metastasis in TNF-Related Apoptosis-Inducing Ligand-Deficient Mice

    Erika Cretney;Kazuyoshi Takeda;Hideo Yagita;Moira Glaccum

  • Type I Interferons (IFNs) Regulate Tumor Necrosis Factor–related Apoptosis-inducing Ligand (TRAIL) Expression on Human T Cells: A Novel Mechanism for the Antitumor Effects of Type I IFNs

    Nobuhiko Kayagaki;Noriko Yamaguchi;Masafumi Nakayama;Hiroshi Eto

  • Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

    Alan D. Salama;Tanuja Chitnis;Tanuja Chitnis;Jaime Imitola;Jaime Imitola;Mohammed Javeed I. Ansari

  • Differential regulation of IκB kinase α and β by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

    Hiroyasu Nakano;Masahisa Shindo;Sachiko Sakon;Shigeyuki Nishinaka

Frequent Co-Authors

Ko Okumura
Ko Okumura Juntendo University
Hisaya Akiba
Hisaya Akiba Juntendo University
Miyuki Azuma
Miyuki Azuma Tokyo Medical and Dental University
Kazuyoshi Takeda
Kazuyoshi Takeda Juntendo University
Mark J. Smyth
Mark J. Smyth QIMR Berghofer Medical Research Institute
Mohamed H. Sayegh
Mohamed H. Sayegh American University of Beirut
Hiroyasu Nakano
Hiroyasu Nakano Toho University
Nader Najafian
Nader Najafian Brigham and Women's Hospital
Tetsuji Kobata
Tetsuji Kobata Tokyo Medical and Dental University

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