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2025
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Immunology
USA
2026

D-Index & Metrics

Best Scientists

D-Index
169
Citations
132533
World Ranking
897
National Ranking
533

Immunology

D-Index
173
Citations
141771
World Ranking
48
National Ranking
35

Medicine

D-Index
173
Citations
141902
World Ranking
468
National Ranking
276

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Immunology in United States Leader Award
  • 2019 - Benjamin Franklin Medal, Franklin Institute
  • 2019 - Distinguished Fellows of the American Association of Immunologists (AAI)
  • 2018 - King Faisal Prize
  • 2018 - Dr. Paul Janssen Award for Biomedical Research, Johnson & Johnson for pioneering a novel and effective strategy to harness the immune system for treating solid tumor cancers.
  • 2018 - Nobel Prize for their discovery of cancer therapy by inhibition of negative immune regulation
  • 2018 - Albany Medical Center Prize in Medicine and Biomedical Research
  • 2018 - Jessie Stevenson Kovalenko Medal, US National Academy of Sciences For important medical discoveries related to the body’s immune response to tumors.
  • 2017 - Fellow of the American Academy of Arts and Sciences
  • 2017 - BBVA Foundation Frontiers of Knowledge Award
  • 2015 - Paul Ehrlich and Ludwig Darmstaedter Prize
  • 2014 - Louisa Gross Horwitz Prize, Columbia University
  • 2014 - Szent-Györgyi Prize for Progress in Cancer Research, National Foundation for Cancer Research (NFCR)
  • 2014 - Breakthrough Prize in Life Sciences for the discovery of T cell checkpoint blockade as effective cancer therapy.
  • 2014 - Canada Gairdner International Award
  • 2011 - American Association of Immunologists Lifetime Achievement Award
  • 2011 - AAI Lifetime Achievement Award, American Association of Immunologists
  • 2008 - AAI-Steinman Award for Human Immunology Research, American Association of Immunologists
  • 2007 - Member of the National Academy of Medicine (NAM)
  • 2006 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1997 - Member of the National Academy of Sciences
  • 1930 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

James P. Allison is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily focuses on medicine with a significant concentration in immunology and microbiology.

The scientist has contributed extensively to the fields of oncology, immunology, pulmonary and respiratory medicine, molecular biology, and epidemiology. Their main research topics include cancer immunotherapy and biomarkers, CAR-T cell therapy research, immune cell function and interaction, immunotherapy and immune responses, immune cells in cancer, pancreatic and hepatic oncology research, and cancer, stress, anesthesia, and immune response.

James P. Allison has published numerous papers in prominent journals. Some recent publications are:

  • Immune checkpoint therapy-current perspectives and future directions, 2023, Cell
  • Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response, 2021, Science
  • The Next Decade of Immune Checkpoint Therapy, 2021, Cancer Discovery
  • Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial, 2021, Nature Medicine
  • Dissecting the mechanisms of immune checkpoint therapy, 2020, Nature reviews. Immunology

Frequent co-authors in their works include:

  • Padmanee Sharma
  • Sreyashi Basu
  • Jennifer A. Wargo
  • Shalini S. Yadav
  • Sumit K. Subudhi

The most common venues for their publications include:

  • Journal of Clinical Oncology
  • Cancer Research
  • Cancer Immunology Research
  • Clinical Cancer Research
  • Nature

Throughout their career, James P. Allison has received various awards, including:

  • Distinguished Fellows of the American Association of Immunologists (AAI), 2019
  • Benjamin Franklin Medal, Franklin Institute, 2019
  • Albany Medical Center Prize in Medicine and Biomedical Research, 2018
  • Jessie Stevenson Kovalenko Medal, US National Academy of Sciences, 2018, for important medical discoveries related to the body's immune response to tumors
  • Dr. Paul Janssen Award for Biomedical Research, Johnson & Johnson, 2018, for pioneering a novel and effective strategy to harness the immune system for treating solid tumor cancers
  • Nobel Prize, 2018, for their discovery of cancer therapy by inhibition of negative immune regulation
  • King Faisal Prize, 2018
  • Fellow of the American Academy of Arts and Sciences, 2017
  • BBVA Foundation Frontiers of Knowledge Award, 2017
  • Paul Ehrlich and Ludwig Darmstaedter Prize, 2015
  • Louisa Gross Horwitz Prize, Columbia University, 2014
  • Szent-Györgyi Prize for Progress in Cancer Research, National Foundation for Cancer Research (NFCR), 2014
  • Breakthrough Prize in Life Sciences, 2014, for the discovery of T cell checkpoint blockade as effective cancer therapy
  • Canada Gairdner International Award, 2014
  • American Association of Immunologists Lifetime Achievement Award, 2011
  • AAI Lifetime Achievement Award, American Association of Immunologists, 2011
  • AAI-Steinman Award for Human Immunology Research, American Association of Immunologists, 2008
  • Member of the National Academy of Medicine (NAM), 2007
  • Fellow of the American Association for the Advancement of Science (AAAS), 2006
  • Member of the National Academy of Sciences, 1997
  • Fellow of the American Association for the Advancement of Science (AAAS), 1930

Best Publications

  • The future of immune checkpoint therapy

    Padmanee Sharma;James P. Allison

  • Restoring function in exhausted CD8 T cells during chronic viral infection.

    Daniel L. Barber;E. John Wherry;David Masopust;Baogong Zhu

  • Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

    V. Gopalakrishnan;V. Gopalakrishnan;C. N. Spencer;C. N. Spencer;L. Nezi;A. Reuben

  • Enhancement of antitumor immunity by CTLA-4 blockade.

    Dana R. Leach;Matthew F. Krummel;James P. Allison

  • Fundamental Mechanisms of Immune Checkpoint Blockade Therapy

    Spencer C. Wei;Colm R. Duffy;James P. Allison

  • Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival.

    Berna C. Özdemir;Berna C. Özdemir;Tsvetelina Pentcheva-Hoang;Julienne L. Carstens;Xiaofeng Zheng

  • CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.

    Matthew F. Krummel;James P. Allison

  • Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential

    Padmanee Sharma;James P. Allison

  • B cells and tertiary lymphoid structures promote immunotherapy response

    Beth A. Helmink;Sangeetha M. Reddy;Jianjun Gao;Shaojun Zhang

  • Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma

    Michael A. Postow;Margaret K. Callahan;Margaret K. Callahan;Christopher A. Barker;Christopher A. Barker;Yoshiya Yamada;Yoshiya Yamada

  • Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

    Matthew M. Gubin;Xiuli Zhang;Heiko Schuster;Etienne Caron

  • CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones.

    Fiona A. Harding;James G. McArthur;Jane A. Gross;David H. Raulet

  • PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors

    Michael A. Curran;Welby Montalvo;Hideo Yagita;James P. Allison

  • Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

    Giao Q. Phan;James C. Yang;Richard M. Sherry;Patrick Hwu

  • The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research

    Martin A. Cheever;Martin A. Cheever;James P. Allison;Andrea S. Ferris;Olivera J. Finn

  • Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma.

    Tyler R. Simpson;Fubin Li;Welby Montalvo-Ortiz;Manuel A. Sepulveda

  • Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells

    Sarah E. Townsend;James P. Allison

  • Combination Immunotherapy of B16 Melanoma Using Anti–Cytotoxic T Lymphocyte–Associated Antigen 4 (Ctla-4) and Granulocyte/Macrophage Colony-Stimulating Factor (Gm-Csf)-Producing Vaccines Induces Rejection of Subcutaneous and Metastatic Tumors Accompanied by Autoimmune Depigmentation

    Andrea van Elsas;Andrea van Elsas;Arthur A. Hurwitz;James P. Allison

  • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses.

    R. P.M. Sutmuller;L. M. Van Duivenvoorde;A. Van Elsas;T. N.M. Schumacher

  • Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

    Hirokazu Matsushita;Hirokazu Matsushita;Matthew D. Vesely;Daniel C. Koboldt;Charles G. Rickert

Frequent Co-Authors

Padmanee Sharma
Padmanee Sharma The University of Texas MD Anderson Cancer Center
Jedd D. Wolchok
Jedd D. Wolchok Cornell University
Jennifer A. Wargo
Jennifer A. Wargo The University of Texas MD Anderson Cancer Center
Patrick Hwu
Patrick Hwu The University of Texas MD Anderson Cancer Center
Jianda Yuan
Jianda Yuan MSD (United States)
Adi Diab
Adi Diab The University of Texas MD Anderson Cancer Center
Naval Daver
Naval Daver The University of Texas MD Anderson Cancer Center
Hagop M. Kantarjian
Hagop M. Kantarjian The University of Texas MD Anderson Cancer Center
Guillermo Garcia-Manero
Guillermo Garcia-Manero The University of Texas MD Anderson Cancer Center
Michael A. Davies
Michael A. Davies The University of Texas MD Anderson Cancer Center

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Related Online Degrees & Career Pathways

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