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D-Index & Metrics

Medicine

D-Index
103
Citations
54893
World Ranking
7205
National Ranking
3780

Overview

Michael A. Davies is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research spans across several intersecting fields within medicine and biomedical science, especially focusing on oncology and molecular biology.

Their extensive body of work includes a total of 387 publications in Medicine and 177 in Biochemistry, Genetics, and Molecular Biology. Key subfields include Oncology, Molecular Biology, Pulmonary and Respiratory Medicine, Immunology, and Biomedical Engineering, reflecting a multidisciplinary approach to cancer research and treatment.

Davies has contributed significantly to research in the areas of cancer immunotherapy and biomarkers, melanoma and MAPK pathways, brain metastases and treatment, CAR-T cell therapy research, immunotherapy and immune responses, cutaneous melanoma detection and management, and nanoplatforms for cancer theranostics.

Frequent co-authors collaborating with Davies include:

  • Jennifer L. McQuade
  • Adi Diab
  • Hussein A. Tawbi
  • Elizabeth M. Burton
  • Rodabe N. Amaria

Their work has been published predominantly in several scientific venues, with major contributions in:

  • Journal of Clinical Oncology (40 publications)
  • Cancer Research (30 publications)
  • Annals of Oncology (11 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (11 publications)
  • Neuro-Oncology Advances (10 publications)

Selected recent publications highlight Davies's involvement in advancing understanding of immunotherapy and melanoma treatment:

  • "B cells and tertiary lymphoid structures promote immunotherapy response", 2020, Nature
  • "Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response", 2021, Science
  • "Pathological response and survival with neoadjuvant therapy in melanoma: a pooled analysis from the International Neoadjuvant Melanoma Consortium (INMC)", 2021, Nature Medicine
  • "Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade", 2021, Nature Medicine
  • "Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity", 2022, Cancer Cell

Best Publications

  • Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

    V. Gopalakrishnan;V. Gopalakrishnan;C. N. Spencer;C. N. Spencer;L. Nezi;A. Reuben

  • Genomic Classification of Cutaneous Melanoma

    Rehan Akbani;Kadir C. Akdemir;B. Arman Aksoy;Monique Albert

  • A landscape of driver mutations in melanoma

    Eran Hodis;Ian R. Watson;Ian R. Watson;Gregory V. Kryukov;Gregory V. Kryukov;Gregory V. Kryukov;Stefan T. Arold

  • B cells and tertiary lymphoid structures promote immunotherapy response

    Beth A. Helmink;Sangeetha M. Reddy;Jianjun Gao;Shaojun Zhang

  • Loss of PTEN Promotes Resistance to T Cell–Mediated Immunotherapy

    Weiyi Peng;Jie Qing Chen;Chengwen Liu;Shruti Malu

  • Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma.

    Caroline Robert;Jean J Grob;Daniil Stroyakovskiy;Boguslawa Karaszewska

  • Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial

    Georgina V. Long;Uwe Trefzer;Michael A. Davies;Richard F. Kefford

  • Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.

    Pei Ling Chen;Whijae Roh;Alexandre Reuben;Zachary A. Cooper

  • NRAS mutation status is an independent prognostic factor in metastatic melanoma.

    John A. Jakob;Roland L. Bassett;Chaan S. Ng;Jonathan L. Curry

  • Anti-PD-1 therapy in patients with advanced melanoma and preexisting autoimmune disorders or major toxicity with ipilimumab

    Alexander M. Menzies;Alexander M. Menzies;D. B. Johnson;S. Ramanujam;V. G. Atkinson

  • Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance

    Whijae Roh;Pei Ling Chen;Alexandre Reuben;Christine N. Spencer

  • Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

    Rodabe N. Amaria;Sangeetha M. Reddy;Hussein A. Tawbi;Michael A. Davies

  • Dabrafenib plus trametinib in patients with BRAFV600-mutant melanoma brain metastases (COMBI-MB): a multicentre, multicohort, open-label, phase 2 trial

    Michael A. Davies;Philippe Saiag;Caroline Robert;Jean Jacques Grob

  • Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study.

    G. V. Long;K. T. Flaherty;D. Stroyakovskiy;H. Gogas

  • Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis

    Jennifer L. McQuade;Carrie R. Daniel;Kenneth R. Hess;Carmen Mak

  • Prognostic Factors for Survival in Melanoma Patients with Brain Metastases

    Michael A. Davies;Ping Liu;Susan McIntyre;Kevin B. Kim

  • AKT-Independent Signaling Downstream of Oncogenic PIK3CA Mutations in Human Cancer

    Krishna M. Vasudevan;David A. Barbie;David A. Barbie;Michael A. Davies;Rosalia Rabinovsky

  • Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy.

    Tina Cascone;Jodi A. McKenzie;Rina M. Mbofung;Simone Punt

  • Exome sequencing identifies GRIN2A as frequently mutated in melanoma

    Xiaomu Wei;Vijay Walia;Jimmy C Lin;Jamie K Teer

  • The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells

    Yiling Lu;Yue Zhen Lin;Ruth LaPushin;Bruce Cuevas

Frequent Co-Authors

Patrick Hwu
Patrick Hwu The University of Texas MD Anderson Cancer Center
Jennifer A. Wargo
Jennifer A. Wargo The University of Texas MD Anderson Cancer Center
Jeffrey E. Gershenwald
Jeffrey E. Gershenwald The University of Texas MD Anderson Cancer Center
Alexander J. Lazar
Alexander J. Lazar The University of Texas MD Anderson Cancer Center
Adi Diab
Adi Diab The University of Texas MD Anderson Cancer Center
Georgina V. Long
Georgina V. Long University of Sydney
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Keith T. Flaherty
Keith T. Flaherty Harvard University
Victor G. Prieto
Victor G. Prieto The University of Texas MD Anderson Cancer Center
Chantale Bernatchez
Chantale Bernatchez The University of Texas MD Anderson Cancer Center

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