Chantale Bernatchez

Overview

Best Publications

• Loss of PTEN Promotes Resistance to T Cell–Mediated Immunotherapy

  Weiyi Peng;Jie Qing Chen;Chengwen Liu;Shruti Malu

  1592
  Citations

• A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

  Livnat Jerby-Arnon;Parin Shah;Michael S. Cuoco;Christopher Rodman

  1386
  Citations

• Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

  Jianjun Gao;Lewis Zhichang Shi;Hao Zhao;Jianfeng Chen

  1331
  Citations

• Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy.

  Tina Cascone;Jodi A. McKenzie;Rina M. Mbofung;Simone Punt

  584
  Citations

• Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial.

  Tina Cascone;William N. William;Annikka Weissferdt;Cheuk H. Leung

  574
  Citations

• Specific lymphocyte subsets predict response to adoptive cell therapy using expanded autologous tumor-infiltrating lymphocytes in metastatic melanoma patients

  Laszlo G. Radvanyi;Chantale Bernatchez;Minying Zhang;Patricia S. Fox

  499
  Citations

• Combining Immune Checkpoint Blockade and Tumor-Specific Vaccine for Patients With Incurable Human Papillomavirus 16-Related Cancer: A Phase 2 Clinical Trial.

  Erminia Massarelli;William William;Faye Johnson;Merrill Kies

  466
  Citations

• Identification of bacteria-derived HLA-bound peptides in melanoma

  Shelly Kalaora;Adi Nagler;Deborah Nejman;Michal Alon

  412
  Citations

• Oncogenic BRAF(V600E) Promotes Stromal Cell-Mediated Immunosuppression Via Induction of Interleukin-1 in Melanoma

  Jahan S. Khalili;Shujuan Liu;Tania G. Rodríguez-Cruz;Mayra Whittington

  339
  Citations

• Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes for metastatic melanoma: current status and future outlook.

  Richard Wu;Marie Andrée Forget;Jessica Chacon;Jessica Chacon;Chantale Bernatchez

  322
  Citations

• Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer.

  Jorge Blando;Anu Sharma;Maria Gisela Higa;Hao Zhao

  321
  Citations

• Validation of multiplex immunofluorescence panels using multispectral microscopy for immune-profiling of formalin-fixed and paraffin-embedded human tumor tissues.

  Edwin R. Parra;Naohiro Uraoka;Mei Jiang;Pamela Cook

  281
  Citations

• Deep learning-based prediction of the T cell receptor–antigen binding specificity

  Tianshi Lu;Ze Zhang;James Zhu;Yunguan Wang

  276
  Citations

• Bempegaldesleukin (NKTR-214) plus Nivolumab in Patients with Advanced Solid Tumors: Phase I Dose-Escalation Study of Safety, Efficacy, and Immune Activation (PIVOT-02)

  Adi Diab;Nizar M. Tannir;Salah Eddine Bentebibel;Patrick Hwu

  244
  Citations

• Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion.

  Chris J. Frangieh;Johannes C. Melms;Pratiksha I. Thakore;Kathryn R. Geiger-Schuller;Kathryn R. Geiger-Schuller

  239
  Citations

• A First-in-Human Study and Biomarker Analysis of NKTR-214, a Novel IL2Rβγ-Biased Cytokine, in Patients with Advanced or Metastatic Solid Tumors

  Salah Eddine Bentebibel;Michael E. Hurwitz;Chantale Bernatchez;Cara Haymaker

  221
  Citations

• TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence.

  Alexandre Reuben;Rachel Gittelman;Jianjun Gao;Jiexin Zhang

  215
  Citations

• Comprehensive T cell repertoire characterization of non-small cell lung cancer

  Alexandre Reuben;Jiexin Zhang;Shin Heng Chiou;Rachel M. Gittelman

  212
  Citations

• BRAFV600E Co-opts a Conserved MHC Class I Internalization Pathway to Diminish Antigen Presentation and CD8+ T-cell Recognition of Melanoma

  Sherille D. Bradley;Zeming Chen;Brenda Melendez;Amjad Talukder

  177
  Citations

• Neoadjuvant nivolumab (N) or nivolumab plus ipilimumab (NI) for resectable non-small cell lung cancer (NSCLC): Clinical and correlative results from the NEOSTAR study.

  Tina Cascone;William Nassib William;Annikka Weissferdt;Heather Y. Lin

  177
  Citations

• Effect of neoadjuvant chemotherapy on the immune microenvironment in non-small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches.

  Edwin R. Parra;Pamela Villalobos;Carmen Behrens;Mei Jiang

  169
  Citations

• Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma

  Alexandre Reuben;Christine N. Spencer;Peter A. Prieto;Vancheswaran Gopalakrishnan

  149
  Citations