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Eliezer M. Van Allen

Eliezer M. Van Allen

D-Index & Metrics

Medicine

D-Index
107
Citations
77651
World Ranking
6094
National Ranking
3263

Overview

Eliezer M. Van Allen is affiliated with Harvard University in the United States and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research focuses notably on oncology, pulmonary and respiratory medicine, cancer research, molecular biology, and surgery.

The scientist's primary topics of work include cancer genomics and diagnostics, cancer immunotherapy and biomarkers, prostate cancer treatment and research, renal cell carcinoma treatment, bladder and urothelial cancer treatments, radiomics and machine learning in medical imaging, as well as ferroptosis and cancer prognosis.

Van Allen has published frequently in several academic venues, most prominently in the Journal of Clinical Oncology, Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Clinical Cancer Research, and Annals of Oncology.

Some of their recent papers include:

  • Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma, 2020, Nature Medicine
  • Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma, 2021, Cancer Cell
  • Biologically informed deep neural network for prostate cancer discovery, 2021, Nature
  • Beyond conventional immune-checkpoint inhibition - novel immunotherapies for renal cell carcinoma, 2021, Nature Reviews Clinical Oncology
  • Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels, 2022, JAMA Oncology

Van Allen collaborates frequently with several coauthors, including Toni K. Choueiri, Jihye Park, Sabrina Y. Camp, David A. Braun, and Ziad Bakouny.

Their research spans multiple important medical and biological subfields such as pulmonary and respiratory medicine, oncology, cancer research, molecular biology, and surgery, reflecting a multidisciplinary approach to understanding and treating cancer and related diseases.

Best Publications

  • Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

    Itay Tirosh;Benjamin Izar;Benjamin Izar;Sanjay M. Prakadan;Marc H. Wadsworth

  • Integrative clinical genomics of advanced prostate cancer

    Dan Robinson;Eliezer M. Van Allen;Eliezer M. Van Allen;Yi Mi Wu;Nikolaus Schultz

  • Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

    Nicholas McGranahan;Nicholas McGranahan;Andrew J. S. Furness;Rachel Rosenthal;Sofie Ramskov

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

    Eliezer M. Van Allen;Eliezer M. Van Allen;Diana Miao;Diana Miao;Bastian Schilling;Sachet A. Shukla;Sachet A. Shukla

  • Genomic Classification of Cutaneous Melanoma

    Rehan Akbani;Kadir C. Akdemir;B. Arman Aksoy;Monique Albert

  • The Molecular Taxonomy of Primary Prostate Cancer

    Adam Abeshouse;Jaeil Ahn;Rehan Akbani;Adrian Ally

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

    Benjamin J. Raphael;Ralph H. Hruban;Andrew J. Aguirre;Richard A. Moffitt

  • Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

    Christopher E. Barbieri;Sylvan C. Baca;Sylvan C. Baca;Michael S. Lawrence;Francesca Demichelis;Francesca Demichelis

  • Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

    Colin C. Pritchard;Joaquin Mateo;Michael F. Walsh;Navonil De Sarkar

  • Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer

    Himisha Beltran;Himisha Beltran;Davide Prandi;Juan Miguel Mosquera;Juan Miguel Mosquera;Matteo Benelli

  • Punctuated Evolution of Prostate Cancer Genomes

    Sylvan C Baca;Davide Prandi;Michael S Lawrence;Juan Miguel Mosquera

  • A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

    Livnat Jerby-Arnon;Parin Shah;Michael S. Cuoco;Christopher Rodman

  • Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma

    Diana Miao;Diana Miao;Claire A. Margolis;Claire A. Margolis;Wenhua Gao;Martin H. Voss;Martin H. Voss

  • In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target

    Robert T. Manguso;Robert T. Manguso;Hans W. Pope;Hans W. Pope;Margaret D. Zimmer;Margaret D. Zimmer;Flavian D. Brown

  • Genomic correlates of clinical outcome in advanced prostate cancer.

    Wassim Abida;Joanna Cyrta;Joanna Cyrta;Glenn Heller;Davide Prandi

  • Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

    Priscilla K. Brastianos;Scott L. Carter;Scott L. Carter;Sandro Santagata;Sandro Santagata;Daniel P. Cahill

  • The Molecular Taxonomy of Primary Prostate Cancer

    Adam Abeshouse;Jaeil Ahn;Rehan Akbani;Adrian Ally

  • Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

    I. Tirosh;B. Izar;D. Treacy;J. J. Trombetta

Frequent Co-Authors

Levi A. Garraway
Levi A. Garraway Roche (United States)
Gad Getz
Gad Getz Broad Institute
Toni K. Choueiri
Toni K. Choueiri Harvard University
Scott L. Carter
Scott L. Carter Harvard University
Sabina Signoretti
Sabina Signoretti Brigham and Women's Hospital
David R. Liu
David R. Liu Broad Institute
Mary-Ellen Taplin
Mary-Ellen Taplin Harvard University
Joaquim Bellmunt
Joaquim Bellmunt Beth Israel Deaconess Medical Center
Catherine J. Wu
Catherine J. Wu Harvard University
Matthew Meyerson
Matthew Meyerson Harvard University

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