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Best Scientists
2025
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Medicine
Switzerland
2026

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Best Scientists

D-Index
182
Citations
150780
World Ranking
571
National Ranking
6

Medicine

D-Index
182
Citations
159038
World Ranking
339
National Ranking
3

Research.com Recognitions

  • 2026 - Research.com Medicine in Switzerland Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Medicine in Switzerland Leader Award
  • 2023 - Research.com Medicine in Switzerland Leader Award
  • 2022 - Research.com Medicine in Switzerland Leader Award
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Mark A. Rubin is affiliated with the University of Bern in Switzerland and has a research portfolio concentrated mainly in Medicine and Biochemistry, Genetics and Molecular Biology.

Their work spans several subfields including Pulmonary and Respiratory Medicine, Molecular Biology, Cancer Research, Oncology, and Surgery. Rubin's primary research topics focus on Prostate Cancer Treatment and Research, Cancer Genomics and Diagnostics, Prostate Cancer Diagnosis and Treatment, Cancer-related molecular mechanisms research, Cancer, Lipids, and Metabolism, Epigenetics and DNA Methylation, and RNA Research and Splicing.

Rubin has contributed extensively to the scientific literature, with numerous publications in frequent venues such as Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), European Urology, Histopathology, and Cancer Research.

Notable recent papers include:

  • The 2022 World Health Organization Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours (2022) published in European Urology
  • Analyses of non-coding somatic drivers in 2,658 cancer whole genomes (2020) published in Nature
  • Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019 (2020) published in European Urology
  • The 2019 Genitourinary Pathology Society (GUPS) White Paper on Contemporary Grading of Prostate Cancer (2020) published in Archives of Pathology & Laboratory Medicine
  • The 2022 World Health Organization Classification of Tumors of the Urinary System and Male Genital Organs-Part B: Prostate and Urinary Tract Tumors (2022) published in European Urology

Frequent co-authors collaborating with Rubin include Salvatore Piscuoglio, Himisha Beltran, Andrea Sboner, Olivier Elemento, and Holger Moch.

The scientist has received recognition as a Member of the Association of American Physicians.

Best Publications

  • Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer

    S.A. Tomlins;D.R. Rhodes;S. Perner;S.M. Dhanasekaran

  • The landscape of somatic copy-number alteration across human cancers

    Rameen Beroukhim;Craig H. Mermel;Craig H. Mermel;Dale Porter;Guo Wei

  • Comprehensivemolecular characterization of clear cell renal cell carcinoma

    Chad J. Creighton;Margaret Morgan;Preethi H. Gunaratne;Preethi H. Gunaratne;David A. Wheeler

  • Integrative clinical genomics of advanced prostate cancer

    Dan Robinson;Eliezer M. Van Allen;Eliezer M. Van Allen;Yi Mi Wu;Nikolaus Schultz

  • The polycomb group protein EZH2 is involved in progression of prostate cancer

    Sooryanarayana Varambally;Saravana M. Dhanasekaran;Ming Zhou;Terrence R. Barrette

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • The Molecular Taxonomy of Primary Prostate Cancer

    Adam Abeshouse;Jaeil Ahn;Rehan Akbani;Adrian Ally

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer.

    Joaquin Mateo;Suzanne Carreira;Shahneen Sandhu;Susana Miranda

  • Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

    Garrett M Frampton;Alex Fichtenholtz;Geoff A Otto;Kai Wang

  • Delineation of prognostic biomarkers in prostate cancer

    Saravana M. Dhanasekaran;Terrence R. Barrette;Debashis Ghosh;Rajal Shah

  • EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

    Celina G. Kleer;Qi Cao;Sooryanarayana Varambally;Ronglai Shen

  • Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

    Levi A. Garraway;Hans R. Widlund;Mark A. Rubin;Gad Getz

  • Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

    Christopher E. Barbieri;Sylvan C. Baca;Sylvan C. Baca;Michael S. Lawrence;Francesca Demichelis;Francesca Demichelis

  • Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

    Colin C. Pritchard;Joaquin Mateo;Michael F. Walsh;Navonil De Sarkar

  • Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer

    Himisha Beltran;Himisha Beltran;Davide Prandi;Juan Miguel Mosquera;Juan Miguel Mosquera;Matteo Benelli

  • Organoid cultures derived from patients with advanced prostate cancer

    Dong Gao;Ian Vela;Andrea Sboner;Phillip J Iaquinta

  • The Molecular Taxonomy of Primary Prostate Cancer

    Adam Abeshouse;Jaeil Ahn;Rehan Akbani;Adrian Ally

Frequent Co-Authors

Francesca Demichelis
Francesca Demichelis University of Trento
Juan Miguel Mosquera
Juan Miguel Mosquera Cornell University
Andrea Sboner
Andrea Sboner Cornell University
Himisha Beltran
Himisha Beltran Harvard University
Arul M. Chinnaiyan
Arul M. Chinnaiyan University of Michigan–Ann Arbor
Sven Perner
Sven Perner University of Lübeck
Olivier Elemento
Olivier Elemento Cornell University
Levi A. Garraway
Levi A. Garraway Roche (United States)
Scott A. Tomlins
Scott A. Tomlins University of Michigan–Ann Arbor
Matthew Meyerson
Matthew Meyerson Harvard University

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