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Medicine

D-Index
75
Citations
34312
World Ranking
18971
National Ranking
994

Overview

Sven Perner is affiliated with the University of Lübeck in Germany and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research spans a significant number of publications with a focus on oncology, pulmonary and respiratory medicine, molecular biology, immunology, and surgery.

Their scientific output includes recent papers addressing various cancer research topics such as the tumor microenvironment, cancer immunotherapy, and the genetic mechanisms underlying oncogene amplification. Some notable publications are:

  • High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer, 2022, Cancer Cell
  • Novel approaches to target the microenvironment of bone metastasis, 2021, Nature Reviews Clinical Oncology
  • Comprehensive characterization of the prostate tumor microenvironment identifies CXCR4/CXCL12 crosstalk as a novel antiangiogenic therapeutic target in prostate cancer, 2022, Molecular Cancer
  • Chromothripsis followed by circular recombination drives oncogene amplification in human cancer, 2021, Nature Genetics
  • Aggressive variants of prostate cancer: underlying mechanisms of neuroendocrine transdifferentiation, 2022, Journal of Experimental & Clinical Cancer Research

Their frequent co-authors include Anne Offermann, Julika Ribbat-Idel, Jutta Kirfel, Christian Idel, and Axel S. Merseburger.

Their research has been published in a range of scientific journals, with the most frequent venues being:

  • Der Pathologe
  • International Journal of Molecular Sciences
  • Laryngo-Rhino-Otologie
  • Frontiers in Medicine
  • PLoS ONE

Sven Perner's primary fields of study involve Medicine and Biochemistry, Genetics and Molecular Biology. Their work is particularly concentrated in the following subfields:

  • Oncology
  • Pulmonary and Respiratory Medicine
  • Molecular Biology
  • Immunology
  • Surgery

They focus on key topics including cancer immunotherapy and biomarkers, prostate cancer treatment and research, head and neck cancer studies, immunotherapy and immune responses, lung cancer research studies, prostate cancer diagnosis and treatment, and bladder and urothelial cancer treatments.

Best Publications

  • Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer

    S.A. Tomlins;D.R. Rhodes;S. Perner;S.M. Dhanasekaran

  • Comprehensive genomic profiles of small cell lung cancer

    Julie George;Jing Shan Lim;Se Jin Jang;Yupeng Cun

  • Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

    Martin Peifer;Lynnette Fernández-Cuesta;Martin L. Sos;Julie George

  • Characterizing the cancer genome in lung adenocarcinoma

    Barbara A. Weir;Barbara A. Weir;Michele S. Woo;Gad Getz;Sven Perner;Sven Perner

  • Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

    Rameen Beroukhim;Gad Getz;Leia Nghiemphu;Jordi Barretina

  • SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

    Adam J. Bass;Adam J. Bass;Hideo Watanabe;Hideo Watanabe;Craig H. Mermel;Craig H. Mermel;Soyoung Yu

  • Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer

    Jonathan Weiss;Martin L. Sos;Danila Seidel;Martin Peifer

  • Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets

    Himisha Beltran;David S. Rickman;Kyung Park;Sung Suk Chae

  • TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort.

    F. Demichelis;K. Fall;S. Perner;S. Perner;O. Andrén

  • TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer

    Sven Perner;Sven Perner;Francesca Demichelis;Rameen Beroukhim;Rameen Beroukhim;Folke H. Schmidt

  • A genomics-based classification of human lung tumors

    Danila Seidel;Thomas Zander;Lukas C. Heukamp;Martin Peifer

  • Telomerase activation by genomic rearrangements in high-risk neuroblastoma

    Martin Peifer;Falk Hertwig;Frederik Roels;Daniel Dreidax

  • Prevention and early detection of prostate cancer

    Jack Cuzick;Mangesh A Thorat;Gerald L Andriole;Otis W Brawley;Otis W Brawley

  • TMPRSS2-ERG Fusion Prostate Cancer: An Early Molecular Event Associated With Invasion

    Sven Perner;Sven Perner;Juan Miguel Mosquera;Francesca Demichelis;Matthias D. Hofer

  • Prostate-specific membrane antigen expression as a predictor of prostate cancer progression

    Sven Perner;Sven Perner;Matthias D. Hofer;Matthias D. Hofer;Robert Kim;Robert Kim;Rajal B. Shah

  • Gleason Score and Lethal Prostate Cancer: Does 3 + 4 = 4 + 3?

    Jennifer R. Stark;Sven Perner;Meir J. Stampfer;Jennifer A. Sinnott

  • An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

    Catherine A. Brownstein;Alan H. Beggs;Nils Homer;Barry Merriman

  • Estrogen-Dependent Signaling in a Molecularly Distinct Subclass of Aggressive Prostate Cancer

    Sunita R. Setlur;Kirsten D. Mertz;Yujin Hoshida;Yujin Hoshida;Francesca Demichelis

  • The role of SPINK1 in ETS rearrangement-negative prostate cancers.

    Scott A. Tomlins;Daniel R. Rhodes;Jianjun Yu;Sooryanarayana Varambally

  • Imaging Prostate Cancer with 11C-Choline PET/CT

    Sven N Reske;Norbert M Blumstein;Bernd Neumaier;Hans-Werner Gottfried

Frequent Co-Authors

Mark A. Rubin
Mark A. Rubin University of Bern
Francesca Demichelis
Francesca Demichelis University of Trento
Arul M. Chinnaiyan
Arul M. Chinnaiyan University of Michigan–Ann Arbor
Matthew Meyerson
Matthew Meyerson Harvard University
Roman K. Thomas
Roman K. Thomas University of Cologne
Rameen Beroukhim
Rameen Beroukhim Harvard University
Holger Moch
Holger Moch University of Zurich
Meir J. Stampfer
Meir J. Stampfer Harvard University
Lorelei A. Mucci
Lorelei A. Mucci Harvard University
Hans-Olov Adami
Hans-Olov Adami Karolinska Institute

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