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Roman K. Thomas

Roman K. Thomas

D-Index & Metrics

Medicine

D-Index
83
Citations
46214
World Ranking
15352
National Ranking
813

Overview

Roman K. Thomas is affiliated with the University of Cologne in Germany and focuses their research primarily in the intersecting fields of medicine and biochemistry, genetics, and molecular biology. Their work extensively covers oncology, molecular biology, cancer research, epidemiology, and pulmonary and respiratory medicine.

The scientist's research addresses multiple specialized topics, including:

  • Lung Cancer Research Studies
  • RNA modifications and cancer
  • Neuroendocrine Tumor Research Advances
  • Cancer Genomics and Diagnostics
  • Cancer therapeutics and mechanisms
  • Neuroblastoma Research and Treatments
  • Lung Cancer Treatments and Mutations

Roman K. Thomas has published numerous research papers in leading scientific journals. Recent significant publications include:

  • "Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes," 2021, Nature Communications
  • "Chromothripsis followed by circular recombination drives oncogene amplification in human cancer," 2021, Nature Genetics
  • "Therapeutic targeting of the mevalonate-geranylgeranyl diphosphate pathway with statins overcomes chemotherapy resistance in small cell lung cancer," 2022, Nature Cancer
  • "Evolutionary trajectories of small cell lung cancer under therapy," 2024, Nature
  • "MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I," 2021, Nature Communications

Their collaborations include frequent co-authors in the field, such as Julie George, Martin Peifer, Reinhard Büttner, Hans Christian Reinhardt, and Johannes Brägelmann.

Roman K. Thomas's work appears regularly in prominent publication venues including:

  • Cancer Research
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Thoracic Oncology
  • Journal of Clinical Oncology

Best Publications

  • Comprehensive genomic characterization of squamous cell lung cancers

    Peter S. Hammerman;Doug Voet;Michael S. Lawrence;Douglas Voet

  • Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

    David A. Barbie;Pablo Tamayo;Jesse S. Boehm;So Young Kim

  • Somatic mutations affect key pathways in lung adenocarcinoma

    Li Ding;Gad Getz;David A. Wheeler;Elaine R. Mardis

  • Comprehensive genomic profiles of small cell lung cancer

    Julie George;Jing Shan Lim;Se Jin Jang;Yupeng Cun

  • Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing

    Marcin Imielinski;Alice H. Berger;Alice H. Berger;Peter S. Hammerman;Peter S. Hammerman;Bryan Hernandez

  • Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

    Martin Peifer;Lynnette Fernández-Cuesta;Martin L. Sos;Julie George

  • Characterizing the cancer genome in lung adenocarcinoma

    Barbara A. Weir;Barbara A. Weir;Michele S. Woo;Gad Getz;Sven Perner;Sven Perner

  • Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

    Rameen Beroukhim;Gad Getz;Leia Nghiemphu;Jordi Barretina

  • EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer

    Jussi P. Koivunen;Craig Mermel;Kreshnik Zejnullahu;Carly Murphy

  • High-throughput oncogene mutation profiling in human cancer

    Roman K. Thomas;Alissa C. Baker;Ralph M. DeBiasi;Ralph M. DeBiasi;Wendy Winckler;Wendy Winckler

  • Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer

    Jonathan Weiss;Martin L. Sos;Danila Seidel;Martin Peifer

  • Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data.

    Charles M. Rudin;John T. Poirier;Lauren Averett Byers;Caroline Dive

  • Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine

    Marc Beyer;Matthias Kochanek;Matthias Kochanek;Kamruz Darabi;Kamruz Darabi;Alexey Popov;Alexey Popov

  • A genomics-based classification of human lung tumors

    Danila Seidel;Thomas Zander;Lukas C. Heukamp;Martin Peifer

  • PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR

    Martin L. Sos;Mirjam Koker;Barbara A. Weir;Stefanie Heynck

  • Optimization of Dosing for EGFR-Mutant Non–Small Cell Lung Cancer with Evolutionary Cancer Modeling

    Juliann Chmielecki;Jasmine Y Foo;Geoffrey R. Oxnard;Katherine Hutchinson

  • Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer

    Peter S. Hammerman;Martin L. Sos;Alex H. Ramos;Chunxiao Xu

  • Telomerase activation by genomic rearrangements in high-risk neuroblastoma

    Martin Peifer;Falk Hertwig;Frederik Roels;Daniel Dreidax

  • MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition

    Gurkan Mollaoglu;Matthew R. Guthrie;Stefanie Böhm;Johannes Brägelmann

  • Prognostic and Predictive Gene Signature for Adjuvant Chemotherapy in Resected Non–Small-Cell Lung Cancer

    Chang Qi Zhu;Keyue Ding;Dan Strumpf;Barbara A. Weir

Frequent Co-Authors

Matthew Meyerson
Matthew Meyerson Harvard University
Jürgen Wolf
Jürgen Wolf University of Cologne
Heidi Greulich
Heidi Greulich Broad Institute
William Pao
William Pao Roche (United States)
Daniel Rauh
Daniel Rauh TU Dortmund University
Kwok-Kin Wong
Kwok-Kin Wong New York University
Rameen Beroukhim
Rameen Beroukhim Harvard University
Levi A. Garraway
Levi A. Garraway Roche (United States)
Reinhard Büttner
Reinhard Büttner University Hospital Cologne
Sven Perner
Sven Perner University of Lübeck

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