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Medicine

D-Index
148
Citations
94351
World Ranking
1231
National Ranking
714

Overview

Ignacio I. Wistuba is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on Oncology, Pulmonary and Respiratory Medicine, Molecular Biology, Cancer Research, and Immunology.

Their work covers a range of topics concentrated on cancer and lung diseases, including:

  • Cancer Immunotherapy and Biomarkers
  • Cancer Genomics and Diagnostics
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Diagnosis and Treatment
  • Lung Cancer Research Studies
  • Immunotherapy and Immune Responses
  • Radiomics and Machine Learning in Medical Imaging

Wistuba has contributed to numerous publications, frequently collaborating with notable coauthors such as John V. Heymach, Edwin R. Parra, Junya Fujimoto, Carmen Behrens, and Don L. Gibbons.

Their recent papers include:

  • PD-L1 as a biomarker of response to immune-checkpoint inhibitors, 2021, Nature Reviews Clinical Oncology
  • Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities, 2021, Cancer Cell
  • Neoadjuvant chemotherapy and nivolumab in resectable non-small-cell lung cancer (NADIM): an open-label, multicentre, single-arm, phase 2 trial, 2020, The Lancet Oncology
  • Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial, 2021, Nature Medicine
  • Liquid Biopsy for Advanced NSCLC: A Consensus Statement From the International Association for the Study of Lung Cancer, 2021, Journal of Thoracic Oncology

Wistuba's research is frequently published in respected scientific journals, with repeated contributions to:

  • Journal of Thoracic Oncology
  • Cancer Research
  • Journal of Clinical Oncology
  • Clinical Cancer Research
  • Nature Communications

Best Publications

  • International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma

    William D Travis;Elisabeth Brambilla;Masayuki Noguchi;Andrew G Nicholson

  • The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification

    William D. Travis;Elisabeth Brambilla;Andrew G. Nicholson;Yasushi Yatabe

  • Somatic mutations affect key pathways in lung adenocarcinoma

    Li Ding;Gad Getz;David A. Wheeler;Elaine R. Mardis

  • Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers

    Hisayuki Shigematsu;Hisayuki Shigematsu;Li Lin;Takao Takahashi;Masaharu Nomura

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs

    Mark G. Kris;Bruce E. Johnson;Lynne D. Berry;David J. Kwiatkowski

  • STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma.

    Ferdinandos Skoulidis;Michael E. Goldberg;Danielle M. Greenawalt;Matthew D. Hellmann

  • PD-L1 as a biomarker of response to immune-checkpoint inhibitors

    Deborah Blythe Doroshow;Sheena Bhalla;Mary Beth Beasley;Lynette M. Sholl

  • Characterizing the cancer genome in lung adenocarcinoma

    Barbara A. Weir;Barbara A. Weir;Michele S. Woo;Gad Getz;Sven Perner;Sven Perner

  • An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

    Lauren Averett Byers;Lixia Diao;Jing Wang;Pierre Saintigny

  • Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial

    Hussein A Tawbi;Melissa Burgess;Vanessa Bolejack;Brian A Van Tine

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression

    Limo Chen;Don Lynn Gibbons;Sangeeta Goswami;Maria Angelica Abdalla Cortez

  • The BATTLE Trial: Personalizing Therapy for Lung Cancer

    Edward S. Kim;Roy S. Herbst;Ignacio Ivan Wistuba;Jiun-Kae Jack Lee

  • Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

    Jianjun Zhang;Junya Fujimoto;Jianhua Zhang;David C. Wedge

  • Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.

    Pei Ling Chen;Whijae Roh;Alexandre Reuben;Zachary A. Cooper

  • Somatic mutations of the HER2 kinase domain in lung adenocarcinomas

    Hisayuki Shigematsu;Hisayuki Shigematsu;Takao Takahashi;Masaharu Nomura;Kuntal Majmudar

  • KRAS Mutation Is an Important Predictor of Resistance to Therapy with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancer

    Erminia Massarelli;Marileila Varella-Garcia;Ximing Tang;Ana C. Xavier

  • Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic Vulnerabilities

    Ferdinandos Skoulidis;Lauren A. Byers;Lixia Diao;Vassiliki A. Papadimitrakopoulou

  • A prospective, multi-institutional, pathologist-based assessment of 4 immunohistochemistry assays for PD-L1 expression in non–small cell lung cancer

    David L. Rimm;Gang Han;Janis M. Taube;Eunhee S. Yi

Frequent Co-Authors

Carmen Behrens
Carmen Behrens The University of Texas MD Anderson Cancer Center
John V. Heymach
John V. Heymach The University of Texas MD Anderson Cancer Center
John D. Minna
John D. Minna The University of Texas Southwestern Medical Center
J. Jack Lee
J. Jack Lee The University of Texas MD Anderson Cancer Center
Jing Wang
Jing Wang The University of Texas MD Anderson Cancer Center
Cesar A. Moran
Cesar A. Moran The University of Texas MD Anderson Cancer Center
Humam Kadara
Humam Kadara The University of Texas MD Anderson Cancer Center
Waun Ki Hong
Waun Ki Hong The University of Texas MD Anderson Cancer Center
Stephen G. Swisher
Stephen G. Swisher The University of Texas MD Anderson Cancer Center
Don L. Gibbons
Don L. Gibbons The University of Texas MD Anderson Cancer Center

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