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Shinichi Toyooka

Shinichi Toyooka

D-Index & Metrics

Medicine

D-Index
80
Citations
31572
World Ranking
16929
National Ranking
533

Overview

Shinichi Toyooka is affiliated with Okayama University in Japan and has a substantial body of research primarily in the field of Medicine. Their work is especially concentrated in subfields including Pulmonary and Respiratory Medicine, Surgery, Oncology, Molecular Biology, and Cancer Research.

The main research topics covered by their publications include:

  • Transplantation: Methods and Outcomes
  • Lung Cancer Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations
  • Organ Transplantation Techniques and Outcomes
  • Renal Transplantation Outcomes and Treatments
  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers

Toyooka has collaborated frequently with a number of researchers, including:

  • Seiichiro Sugimoto
  • Mikio Okazaki
  • Hiromasa Yamamoto
  • Kazuhiko Shien
  • Ken Suzawa

Their research is often published in several notable venues, particularly:

  • The Journal of Heart and Lung Transplantation
  • Surgery Today
  • Cancer Research
  • PubMed
  • Journal of Clinical Oncology

Some recent publications include:

  • Immune evasion through mitochondrial transfer in the tumour microenvironment, 2025, Nature
  • Clinical Impacts of EGFR Mutation Status: Analysis of 5780 Surgically Resected Lung Cancer Cases, 2020, The Annals of Thoracic Surgery
  • Randomized Phase III Study of Pemetrexed Plus Cisplatin Versus Vinorelbine Plus Cisplatin for Completely Resected Stage II to IIIA Nonsquamous Non-Small-Cell Lung Cancer, 2020, Journal of Clinical Oncology
  • Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2.1), 2020, International Journal of Clinical Oncology
  • DV200 Index for Assessing RNA Integrity in Next-Generation Sequencing, 2020, BioMed Research International

Best Publications

  • Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial

    Tetsuya Mitsudomi;Satoshi Morita;Yasushi Yatabe;Shunichi Negoro

  • Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers

    Hisayuki Shigematsu;Hisayuki Shigematsu;Li Lin;Takao Takahashi;Masaharu Nomura

  • Epigenetic Inactivation of RASSF1A in Lung and Breast Cancers and Malignant Phenotype Suppression

    David G. Burbee;Eva Forgacs;Sabine Zöchbauer-Müller;Latha Shivakumar

  • Somatic mutations of the HER2 kinase domain in lung adenocarcinomas

    Hisayuki Shigematsu;Hisayuki Shigematsu;Takao Takahashi;Masaharu Nomura;Kuntal Majmudar

  • The Relationship between Epidermal Growth Factor Receptor Mutations and Clinicopathologic Features in Non–Small Cell Lung Cancers

    Masaki Tokumo;Shinichi Toyooka;Katsuyuki Kiura;Hisayuki Shigematsu

  • Aberrant Promoter Methylation Profile of Bladder Cancer and Its Relationship to Clinicopathological Features

    Riichiroh Maruyama;Shinichi Toyooka;Kiyomi O. Toyooka;Kenichi Harada

  • Presence of Epidermal Growth Factor Receptor Gene T790M Mutation as a Minor Clone in Non–Small Cell Lung Cancer

    Michio Inukai;Shinichi Toyooka;Sachio Ito;Hiroaki Asano

  • PIK3CA Mutations and Copy Number Gains in Human Lung Cancers

    Hiromasa Yamamoto;Hiromasa Yamamoto;Hisayuki Shigematsu;Hisayuki Shigematsu;Masaharu Nomura;William W. Lockwood

  • Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1

    Kadoaki Ohashi;Lecia V. Sequist;Maria E. Arcila;Teresa Moran

  • Aberrant Promoter Methylation Profile of Prostate Cancers and Its Relationship to Clinicopathological Features

    Riichiroh Maruyama;Shinichi Toyooka;Kiyomi O. Toyooka;Arvind K. Virmani

  • The TP53 gene, tobacco exposure, and lung cancer.

    Shinichi Toyooka;Shinichi Toyooka;Toshihide Tsuda;Adi F. Gazdar

  • Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer

    Shinichi Toyooka;Shinichi Toyooka;Riichiroh Maruyama;Kiyomi O. Toyooka;Dale McLerran

  • DNA methylation profiles of lung tumors.

    Shinichi Toyooka;Kiyomi O. Toyooka;Riichiroh Maruyama;Arvind K. Virmani

  • Loss of expression and aberrant methylation of the CDH13 (H-cadherin) gene in breast and lung carcinomas.

    Kiyomi O. Toyooka;Shinichi Toyooka;Arvind K. Virmani;Ubaradka G. Sathyanarayana

  • Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines.

    Kenichi Harada;Shinichi Toyooka;Anirban Maitra;Riichiroh Maruyama

  • Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells

    Kazuhiko Shien;Shinichi Toyooka;Hiromasa Yamamoto;Junichi Soh

  • Genetic predictors of MEK-dependence in non-small cell lung cancer

    Christine A. Pratilas;Aphrothiti J. Hanrahan;Ensar Halilovic;Ensar Halilovic;Yogindra Persaud

  • Detection of EGFR gene mutation in lung cancer by mutant-enriched polymerase chain reaction assay.

    Hiroaki Asano;Shinichi Toyooka;Masaki Tokumo;Kouichi Ichimura

  • Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells.

    Junichi Soh;Junichi Soh;Naoki Okumura;William W. Lockwood;Hiromasa Yamamoto

  • The relationship between epidermal growth factor receptor(EGFR) mutations and clinico-pathological features in non-small cell lung cancers

    Masaki Tokumo;Shinichi Toyooka;Katsuyuki Kiura;Hisayuki Shigematsu

Frequent Co-Authors

Adi F. Gazdar
Adi F. Gazdar The University of Texas Southwestern Medical Center
Masakiyo Sakaguchi
Masakiyo Sakaguchi Okayama University
John D. Minna
John D. Minna The University of Texas Southwestern Medical Center
Keitaro Matsuo
Keitaro Matsuo Nagoya University
Tetsuya Mitsudomi
Tetsuya Mitsudomi Kindai University
Meinoshin Okumura
Meinoshin Okumura Osaka University
Yasushi Yatabe
Yasushi Yatabe Nagoya University
Harvey I. Pass
Harvey I. Pass New York University
Nobuyoshi Shimizu
Nobuyoshi Shimizu Keio University
Akira Yamauchi
Akira Yamauchi Kawasaki Medical School

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