World's Best Scientists 2026 revealed!
James Chih-Hsin Yang

James Chih-Hsin Yang

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Medicine
Taiwan
2026

D-Index & Metrics

Medicine

D-Index
165
Citations
143110
World Ranking
614
National Ranking
2

Research.com Recognitions

  • 2026 - Research.com Medicine in Taiwan Leader Award
  • 2025 - Research.com Medicine in Taiwan Leader Award

Overview

James Chih-Hsin Yang is a researcher affiliated with National Taiwan University in Taiwan, specializing in Medicine, with a particular focus on Oncology, Immunology, and related subfields. Their work predominantly addresses cancer immunotherapy, CAR-T cell therapy, and lung cancer treatment and research.

Yang's research spans several interrelated topics, including:

  • Cancer Immunotherapy and Biomarkers
  • CAR-T cell therapy research
  • Immunotherapy and Immune Responses
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Research Studies
  • Immune Cell Function and Interaction
  • Vaccines and immunoinformatics approaches

Recent publications by Yang illustrate a focus on T cell therapy and tumor immunology:

  • "Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers" (2022), published in Science
  • "Long-Term Follow-Up of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy" (2020), published in Journal of Clinical Oncology
  • "Primary analysis of a randomized, double-blind, phase II study of the anti-TIGIT antibody tiragolumab plus atezolizumab versus placebo as first-line treatment in patients with PD-L1-selected NSCLC (CITYSCAPE)" (2020), published in Journal of Clinical Oncology
  • "A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers" (2022), published in Cancer Cell
  • "Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors" (2022), published in Cancer Immunology Research

Yang's collaboration network includes frequent co-authors such as:

  • Stephanie L. Goff
  • Steven A. Rosenberg
  • Maria R. Parkhurst
  • Ken-ichi Hanada
  • Jared J. Gartner

Their research has been published extensively in several high-profile venues, with the most frequent publication outlets including:

  • Journal of Clinical Oncology
  • Regular and Young Investigator Award Abstracts
  • Cancer Research
  • Journal of Thoracic Oncology
  • Nature Medicine

Yang's contributions build on a foundation in Oncology with a substantial number of publications in this area, supported by knowledge in Immunology, Pulmonary and Respiratory Medicine, Radiology, Nuclear Medicine and Imaging, as well as Molecular Biology.

Best Publications

  • Cancer regression in patients after transfer of genetically engineered lymphocytes

    Richard A. Morgan;Mark E. Dudley;John R. Wunderlich;Marybeth S. Hughes

  • Cancer immunotherapy: moving beyond current vaccines.

    Steven A Rosenberg;James C Yang;Nicholas P Restifo

  • Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

    Mark E. Dudley;John R. Wunderlich;Paul F. Robbins;James C. Yang

  • Phase III Study of Afatinib or Cisplatin Plus Pemetrexed in Patients With Metastatic Lung Adenocarcinoma With EGFR Mutations

    Lecia V. Sequist;James Chih-Hsin Yang;Nobuyuki Yamamoto;Kenneth John O'Byrne

  • A Randomized Trial of Bevacizumab, an Anti–Vascular Endothelial Growth Factor Antibody, for Metastatic Renal Cancer

    James C. Yang;Leah Haworth;Richard M. Sherry;Patrick Hwu

  • Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report.

    S A Rosenberg;B S Packard;P M Aebersold;D Solomon

  • Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2

    Richard A Morgan;James C Yang;Mio Kitano;Mark E Dudley

  • Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T Cell Transfer Immunotherapy

    Steven A. Rosenberg;James C. Yang;Richard M. Sherry;Udai S. Kammula

  • Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer

    Eric Tran;Simon Turcotte;Alena Gros;Paul F. Robbins

  • Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

    Steven A. Rosenberg;James C. Yang;Douglas J. Schwartzentruber;Patrick Hwu

  • AZD9291 in EGFR Inhibitor–Resistant Non–Small-Cell Lung Cancer

    Pasi A. Jänne;James Chih-Hsin Yang;Dong Wan Kim;David Planchard

  • Adoptive cell transfer: a clinical path to effective cancer immunotherapy

    Steven A. Rosenberg;Nicholas P. Restifo;James C. Yang;Richard A. Morgan

  • Adoptive Cell Transfer Therapy Following Non-Myeloablative but Lymphodepleting Chemotherapy for the Treatment of Patients With Refractory Metastatic Melanoma

    Mark E. Dudley;John R. Wunderlich;James C. Yang;Richard M. Sherry

  • Chemotherapy-Refractory Diffuse Large B-Cell Lymphoma and Indolent B-Cell Malignancies Can Be Effectively Treated With Autologous T Cells Expressing an Anti-CD19 Chimeric Antigen Receptor

    James N. Kochenderfer;Mark E. Dudley;Sadik H. Kassim;Robert P.T. Somerville

  • Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1

    Paul F. Robbins;Richard A. Morgan;Steven A. Feldman;James C. Yang

  • Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

    Giao Q. Phan;James C. Yang;Richard M. Sherry;Patrick Hwu

  • Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity.

    James C. Yang;Alfred E. Chang;Alan R. Baker;William F. Sindelar

  • B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells

    James N. Kochenderfer;Mark E. Dudley;Steven A. Feldman;Wyndham H. Wilson

  • Gene Transfer into Humans — Immunotherapy of Patients with Advanced Melanoma, Using Tumor-Infiltrating Lymphocytes Modified by Retroviral Gene Transduction

    Steven A. Rosenberg;Paul Aebersold;Kenneth Cornetta;Attan Kasid

  • Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen.

    Laura A. Johnson;Richard A. Morgan;Mark E. Dudley;Lydie Cassard

Frequent Co-Authors

Steven A. Rosenberg
Steven A. Rosenberg National Institutes of Health
Tony Mok
Tony Mok Chinese University of Hong Kong
Dong-Wan Kim
Dong-Wan Kim Seoul National University Hospital
Lecia V. Sequist
Lecia V. Sequist Harvard University
Yi-Long Wu
Yi-Long Wu Guangdong Provincial People’s Hospital
Nicholas P. Restifo
Nicholas P. Restifo National Institutes of Health
Suzanne L. Topalian
Suzanne L. Topalian Johns Hopkins University
Myung-Ju Ahn
Myung-Ju Ahn Sungkyunkwan University
Chong-Jen Yu
Chong-Jen Yu National Taiwan University
Mark E. Dudley
Mark E. Dudley Novartis (Switzerland)

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