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Immunology

D-Index
76
Citations
20981
World Ranking
1912
National Ranking
934

Overview

T. Mohanakumar is affiliated with Washington University in St. Louis in the United States. Their research activity centers on medical and molecular biology fields, with a particular emphasis on surgery and transplantation. The work also spans nephrology, obstetrics and gynecology, and molecular biology as subfields, reflecting a multidisciplinary approach.

The scientist's publications focus on several main topics, including transplantation methods and outcomes, extracellular vesicles in disease, and renal transplantation outcomes and treatments. Other areas covered include renal diseases and glomerulopathies, COVID-19 impact on reproduction, interstitial lung diseases and idiopathic pulmonary fibrosis, and cancer-related molecular mechanisms research.

Recent research papers authored or coauthored by this scientist include:

  • Role for exosomes with self-antigens and immune regulatory molecules in allo- and auto-immunity leading to chronic immune injury following murine kidney transplantation (2022), Transplant Immunology
  • Low Dose Interleukin-2 Induces Exosomes with Tolerance Markers (PDL1, CD73) and Significantly Delays Development of Chronic Rejection Following Murine Heterotopic Cardiac Transplantation (2021), The Journal of Heart and Lung Transplantation
  • LKB1 Knockdown Triggered PDGFRβ Signaling Leading to Fibrosis and Development of Chronic Lung Allograft Dysfunction (2022), The Journal of Heart and Lung Transplantation
  • Low Dose IL-2 Therapy Induces T Regulatory Cell Derived Circulatory Exosomes Containing PDL1 and CD73 and Abrogates Development of Chronic Cardiac Allograft Rejection (2022), The Journal of Heart and Lung Transplantation
  • Analysis of Humoral and Cellular Immunity of Lung Transplant Recipients Following SARS-CoV-2 Infection and BNT162b2 mRNA Vaccination (2022), The Journal of Heart and Lung Transplantation

Frequent coauthors include:

  • Yoshihiro Itabashi
  • Sandhya Bansal
  • Christin Poulson
  • Timothy P. Fleming
  • Michael A. Smith

Key publication venues for this scientist are:

  • The Journal of Heart and Lung Transplantation (5 publications)
  • Transplant Immunology (1 publication)

Main fields of study represented in the scientist's work include:

  • Medicine (13 publications)
  • Biochemistry, Genetics and Molecular Biology (5 publications)

Subfields explored are:

  • Surgery (6 publications)
  • Molecular Biology (3 publications)
  • Transplantation (2 publications)
  • Nephrology (1 publication)
  • Obstetrics and Gynecology (1 publication)

The research contributions cover various topics centered on transplantation science and immunology, with notable work on extracellular vesicles and immune regulation in transplant contexts. Their work includes studies on chronic rejection, immune tolerance induction, and immune responses following vaccination in transplant recipients.

Best Publications

  • Consensus guidelines on the testing and clinical management issues associated with HLA and non-HLA antibodies in transplantation.

    Brian D. Tait;Caner Süsal;Howard M. Gebel;Peter W. Nickerson

  • 2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology: Introduction of Antibody-Mediated Rejection.

    A J Demetris;C Bellamy;S G Hübscher;J O'Leary

  • Respiratory Viral Infections Are a Distinct Risk for Bronchiolitis Obliterans Syndrome and Death

    Anthony P. Khalifah;Ramsey R. Hachem;Murali M. Chakinala;Kenneth B. Schechtman

  • The Effect of Tolerance to Noninherited Maternal HLA Antigens on the Survival of Renal Transplants from Sibling Donors

    W.J. Burlingham;A.P. Grailer;D.M. Heisey;F.H.J. Claas

  • Persistent and fatal central-nervous-system ECHOvirus infections in patients with agammaglobulinemia.

    Catherine M. Wilfert;Catherine M. Wilfert;Catherine M. Wilfert;Rebecca H. Buckley;Rebecca H. Buckley;Rebecca H. Buckley;T. Mohanakumar;T. Mohanakumar;T. Mohanakumar;John F. Griffith;John F. Griffith;John F. Griffith

  • HLA alleles determine differences in human natural killer cell responsiveness and potency.

    Sung Jin Kim;John B. Sunwoo;Liping Yang;Taewoong Choi

  • Anti-human leukocyte antigen antibodies and preemptive antibody-directed therapy after lung transplantation

    Ramsey R. Hachem;Roger D. Yusen;Bryan F. Meyers;Aviva A. Aloush

  • Development of ELISA-detected anti-HLA antibodies precedes the development of bronchiolitis obliterans syndrome and correlates with progressive decline in pulmonary function after lung transplantation.

    Andrés Jaramillo;Michael Smith;Donna Phelan;Sudhir Sundaresan

  • HLA-A locus mismatches and development of antibodies to HLA after lung transplantation correlate with the development of bronchiolitis obliterans syndrome

    Sudhir Sundaresan;T. Mohanakumar;Michael Smith;Elbert Trulock

  • Comprehensive assessment and standardization of solid phase multiplex-bead arrays for the detection of antibodies to HLA.

    Elaine F. Reed;Ping Rao;Zilu Zhang;Howard Gebel

  • Prevalence and outcome of bronchiolitis obliterans syndrome after lung transplantation

    Sudhir Sundaresan;Elbert P. Trulock;Thallachallour Mohanakumar;Joel D. Cooper

  • De Novo Production of K-α1 Tubulin-Specific Antibodies: Role in Chronic Lung Allograft Rejection

    Trudie A. Goers;Sabarinathan Ramachandran;Aviva Aloush;Elbert Trulock

  • Immunological link between primary graft dysfunction and chronic lung allograft rejection.

    Ankit Bharat;Elbert Kuo;Nancy Steward;Aviva Aloush

  • Effect of development of antibodies to hla and cytomegalovirus mismatch on lung transplantation survival and development of bronchiolitis obliterans syndrome

    Michael A. Smith;Sudhir Sundaresan;T. Mohanakumar;Elbert P. Trulock

  • Late primary graft dysfunction after lung transplantation and bronchiolitis obliterans syndrome.

    H. J. Huang;R. D. Yusen;B. F. Meyers;M. J. Walter

  • Minimal acute rejection after lung transplantation: a risk for bronchiolitis obliterans syndrome.

    Anthony P. Khalifah;Ramsey R. Hachem;Murali M. Chakinala;Roger D. Yusen

  • Antibodies to MHC Class I Induce Autoimmunity: Role in the Pathogenesis of Chronic Rejection

    Naohiko Fukami;Sabarinathan Ramachandran;Deepti Saini;Michael Walter

  • Alloimmunity-induced autoimmunity as a potential mechanism in the pathogenesis of chronic rejection of human lung allografts

    Deepti Saini;Joseph Weber;Sabarinathan Ramachandran;Donna Phelan

  • Antibodies to K-α 1 tubulin and collagen V are associated with chronic rejection after lung transplantation.

    R. R. Hachem;V. Tiriveedhi;G. A. Patterson;A. Aloush

  • Antibody mediated therapy targeting CD47 inhibits tumor progression of hepatocellular carcinoma

    Zhenyu Xiao;Haniee Chung;Babak Banan;Pamela T. Manning

  • Antibodies to Self-Antigens Predispose to Primary Lung Allograft Dysfunction and Chronic Rejection

    Ankit Bharat;Deepti Saini;Nancy Steward;Ramsey Hachem

  • Anti-HLA class I antibody binding to airway epithelial cells induces production of fibrogenic growth factors and apoptotic cell death: a possible mechanism for bronchiolitis obliterans syndrome.

    Andrés Jaramillo;Craig R Smith;Takahiro Maruyama;Leiying Zhang

Frequent Co-Authors

Elbert P. Trulock
Elbert P. Trulock Washington University in St. Louis
William C. Chapman
William C. Chapman Washington University in St. Louis
G. Alexander Patterson
G. Alexander Patterson Washington University in St. Louis
Joel D. Cooper
Joel D. Cooper University of Pennsylvania
Daniel C. Brennan
Daniel C. Brennan Johns Hopkins University
Timothy P. Fleming
Timothy P. Fleming St. Joseph's Hospital and Medical Center
Roger D. Yusen
Roger D. Yusen Washington University in St. Louis
Susan E. Mackinnon
Susan E. Mackinnon Washington University in St. Louis
William E. Gillanders
William E. Gillanders Washington University in St. Louis
Robert M. Senior
Robert M. Senior Washington University in St. Louis

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