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Biology and Biochemistry

D-Index
64
Citations
15030
World Ranking
9644
National Ranking
4258

Overview

William E. Gillanders is affiliated with Washington University in St. Louis in the United States. Their research spans several interconnected fields, primarily focusing on biochemistry, genetics, molecular biology, medicine, immunology, and microbiology.

The main fields of study for this scientist include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Immunology and Microbiology

Their work further delves into specific subfields such as immunology, molecular biology, oncology, cancer research, and radiology, nuclear medicine, and imaging.

Key topics addressed in their research comprise immunotherapy and immune responses, vaccines and immunoinformatics approaches, cancer immunotherapy and biomarkers, monoclonal and polyclonal antibodies research, cancer genomics and diagnostics, pancreatic and hepatic oncology research, and single-cell and spatial transcriptomics.

Frequent publication venues where William E. Gillanders has contributed include:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Genetics
  • Nature
  • Genome Medicine

Noteworthy recent papers authored or co-authored by William E. Gillanders include:

  • "cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity," 2020, Nature
  • "pVACtools: A Computational Toolkit to Identify and Visualize Cancer Neoantigens," 2020, Cancer Immunology Research
  • "Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer," 2022, Nature Genetics
  • "Epigenetic regulation during cancer transitions across 11 tumour types," 2023, Nature
  • "Tumour evolution and microenvironment interactions in 2D and 3D space," 2024, Nature

William E. Gillanders has collaborated frequently with several co-authors, including:

  • S. Peter Goedegebuure
  • Malachi Griffith
  • Jasreet Hundal
  • John M. Herndon
  • Christopher A. Miller

Best Publications

  • Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

    Matthew M. Gubin;Xiuli Zhang;Heiko Schuster;Etienne Caron

  • Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts.

    Shunqiang Li;Dong Shen;Jieya Shao;Robert Crowder

  • EpCAM is overexpressed in breast cancer and is a potential target for breast cancer gene therapy.

    Walid A. Osta;Yian Chen;Kaidi Mikhitarian;Michael Mitas

  • Expression of programmed death ligand 1 (PD-L1) is associated with poor prognosis in human breast cancer

    S. Muenst;A. R. Schaerli;F. Gao;S. Däster;S. Däster

  • The Human Tumor Atlas Network: Charting Tumor Transitions Across Space and Time at Single-Cell Resolution

    Orit Rozenblatt-Rosen;Aviv Regev;Aviv Regev;Aviv Regev;Philipp Oberdoerffer;Tal Nawy

  • cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity

    Stephen T. Ferris;Vivek Durai;Vivek Durai;Renee Wu;Derek J. Theisen

  • Disruption of CCR5-Dependent Homing of Regulatory T Cells Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer

    Marcus C. B. Tan;Peter S. Goedegebuure;Brian A. Belt;Brian Flaherty

  • Targeting both tumour-associated CXCR2+ neutrophils and CCR2+ macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma

    Timothy M Nywening;Brian A Belt;Darren R Cullinan;Roheena Z Panni

  • The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer

    S. Muenst;S. Muenst;S. D. Soysal;S. D. Soysal;F. Gao;E. C. Obermann

  • Effect of zoledronic acid on disseminated tumour cells in women with locally advanced breast cancer: an open label, randomised, phase 2 trial

    Rebecca Aft;Rebecca Aft;Michael Naughton;Kathryn Trinkaus;Mark Watson

  • WDFY4 is required for cross-presentation in response to viral and tumor antigens

    Derek J. Theisen;Jesse T. Davidson;Carlos G. Briseño;Marco Gargaro

  • NeoPalAna: Neoadjuvant Palbociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor, and Anastrozole for Clinical Stage 2 or 3 Estrogen Receptor-Positive Breast Cancer.

    Cynthia X Ma;Feng Gao;Jingqin Luo;Donald W. Northfelt

  • Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth

    Matthew R. Porembka;Jonathan B. Mitchem;Brian A. Belt;Chyi Song Hsieh

  • Quantitative real-time RT-PCR detection of breast cancer micrometastasis using a multigene marker panel.

    Michael Mitas;Kaidi Mikhitarian;Christian Walters;Paul L. Baron

  • Surgical resection of the primary tumor is associated with increased long-term survival in patients with stage IV breast cancer after controlling for site of metastasis.

    Ryan C. Fields;Donna B. Jeffe;Kathryn Trinkaus;Qin Zhang

  • Preclinical and clinical development of neoantigen vaccines

    L. Li;S. P. Goedegebuure;William E. Gillanders

  • Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit

    Zehua Zhu;Amir R. Aref;Travis J. Cohoon;Thanh U. Barbie

  • pVACtools: A Computational Toolkit to Identify and Visualize Cancer Neoantigens.

    Jasreet Hundal;Susanna Kiwala;Joshua McMichael;Christopher A Miller

  • Best practices for bioinformatic characterization of neoantigens for clinical utility

    Megan M. Richters;Huiming Xia;Katie M. Campbell;William E. Gillanders

  • Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53.

    Tarek A. Taha;Tarek A. Taha;Walid Osta;Lina Kozhaya;Jacek Bielawski

Frequent Co-Authors

Timothy P. Fleming
Timothy P. Fleming St. Joseph's Hospital and Medical Center
Elaine R. Mardis
Elaine R. Mardis The Ohio State University
Malachi Griffith
Malachi Griffith Washington University in St. Louis
Obi L. Griffith
Obi L. Griffith Washington University in St. Louis
Matthew J. Ellis
Matthew J. Ellis Baylor College of Medicine
David G. DeNardo
David G. DeNardo Washington University in St. Louis
William G. Hawkins
William G. Hawkins Washington University in St. Louis
Ted H. Hansen
Ted H. Hansen Washington University in St. Louis
T. Mohanakumar
T. Mohanakumar Washington University in St. Louis
Robert D. Schreiber
Robert D. Schreiber Washington University in St. Louis

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