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Biology and Biochemistry

D-Index
69
Citations
17623
World Ranking
7358
National Ranking
3367

Overview

Ted H. Hansen is affiliated with Washington University in St. Louis in the United States. Their research primarily focuses on immunology, microbiology, and medicine, with notable work in biochemistry, genetics, and molecular biology.

The scientist's main fields of study include:

  • Immunology and Microbiology
  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields of research covered by Hansen are:

  • Immunology
  • Molecular Biology
  • Radiology, Nuclear Medicine and Imaging
  • Oncology
  • Epidemiology

The research topics frequently explored include:

  • Immunotherapy and Immune Responses
  • Vaccines and Immunoinformatics Approaches
  • Monoclonal and Polyclonal Antibodies Research
  • CAR-T Cell Therapy Research
  • Immune Cell Function and Interaction
  • Cytomegalovirus and Herpesvirus Research
  • HIV Research and Treatment

Notable recent papers by Ted H. Hansen include:

  • "Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation" (2021, Genome Medicine)
  • "Neoantigen DNA vaccines are safe, feasible, and induce neoantigen-specific immune responses in triple-negative breast cancer patients" (2024, Genome Medicine)
  • "Neoantigen DNA vaccines are safe, feasible, and capable of inducing neoantigen-specific immune responses in patients with triple negative breast cancer" (2021, bioRxiv (Cold Spring Harbor Laboratory))
  • "Metabolomics reveals nucleoside analogs for regulating mucosal-associated invariant T cell responses" (2023, bioRxiv (Cold Spring Harbor Laboratory))

Frequent coauthors who have collaborated with Hansen include:

  • Lijin Li
  • Samuel W. Kim
  • Nancy B. Myers
  • Mark Sturmoski
  • Michael D. McLellan

Hansen's publications often appear in the following venues:

  • Genome Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

    Emmanuel L Gautier;Tal Shay;Tal Shay;Jennifer Miller;Melanie Greter

  • Licensing of natural killer cells by host major histocompatibility complex class I molecules

    Sung Jin Kim;Jennifer Poursine-Laurent;Steven M. Truscott;Lonnie Lybarger

  • Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells

    Marielle C. Gold;Marielle C. Gold;Stefania Cerri;Susan Smyk-Pearson;Meghan E. Cansler

  • Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

    Rangsima Reantragoon;Alexandra Corbett;Isaac G Sakala;Nicholas A Gherardin;Nicholas A Gherardin

  • CD161 ++ CD8 + T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner

    James E. Ussher;Matthew Bilton;Emma Attwod;Jonathan Shadwell

  • MHC class I antigen presentation: learning from viral evasion strategies

    Ted H. Hansen;Marlene Bouvier

  • MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets

    A Kurioka;J E Ussher;C Cosgrove;C Clough

  • Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3.

    Xiaoli Wang;Roger A. Herr;Wei Jen Chua;Lonnie Lybarger

  • Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection.

    Cormac Cosgrove;James E. Ussher;Andri Rauch;Kathleen Gärtner

  • Polyclonal mucosa-associated invariant T cells have unique innate functions in bacterial infection.

    Wei-Jen Chua;Steven M. Truscott;Christopher S. Eickhoff;Azra Blazevic

  • Bcl-2 is upregulated at the CD4^+ CD8^+ stage during positive selection and promotes thymocyte differentiation at several control points

    Gerald P. Linette;Michael J. Grusby;Stephen M. Hedrick;Ted H. Hansen

  • Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

    Rangsima Reantragoon;Lars Kjer-Nielsen;Onisha G Patel;Zhenjun Chen

  • Recognition by CD8 on cytotoxic T lymphocytes is ablated by several substitutions in the class I alpha 3 domain: CD8 and the T-cell receptor recognize the same class I molecule.

    Janet M. Connolly;Ted H. Hansen;Amie L. Ingold;Terry A. Potter

  • MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage

    Marielle C. Gold;James E. McLaren;Joseph A. Reistetter;Sue Smyk-Pearson

  • Alloreactive cytotoxic T lymphocytes generated in the presence of viral- derived peptides show exquisite peptide and MHC specificity

    Martha A. Alexander-Miller;Karen Burke;Ulrich H. Koszinowski;Ted H. Hansen

  • Peptide ligand-induced conformation and surface expression of the Ld class I MHC molecule

    Wen-Rong Lie;Nancy B. Myers;John Gorka;Ronald J. Rubocki

  • Prominence of beta 2-microglobulin, class I heavy chain conformation, and tapasin in the interactions of class I heavy chain with calreticulin and the transporter associated with antigen processing.

    Joyce C. Solheim;Michael R. Harris;Cathy S. Kindle;Ted H. Hansen

  • MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution

    Shouxiong Huang;Emmanuel Martin;Sojung Kim;Lawrence Yu

  • Cutting edge: single-chain trimers of MHC class I molecules form stable structures that potently stimulate antigen-specific T cells and B cells

    Yik Y. L. Yu;Nikolai Netuschil;Lonnie Lybarger;Janet M. Connolly

  • Evidence for MR1 antigen presentation to mucosal-associated invariant T cells

    Shouxiong Huang;Susan Gilfillan;Marina Cella;Michael J. Miley

Frequent Co-Authors

Daved H. Fremont
Daved H. Fremont Washington University in St. Louis
Jamie Rossjohn
Jamie Rossjohn Monash University
David H. Sachs
David H. Sachs Columbia University
Wayne M. Yokoyama
Wayne M. Yokoyama Washington University in St. Louis
William H. Hildebrand
William H. Hildebrand University of Oklahoma Health Sciences Center
Paul Klenerman
Paul Klenerman University of Oxford
Olivier Lantz
Olivier Lantz Institute Curie
William E. Gillanders
William E. Gillanders Washington University in St. Louis
Timothy P. Fleming
Timothy P. Fleming St. Joseph's Hospital and Medical Center
Emmanuel J. H. J. Wiertz
Emmanuel J. H. J. Wiertz Utrecht University

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