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Biology and Biochemistry

D-Index
58
Citations
9477
World Ranking
13426
National Ranking
5700

Overview

Stephen P. Mackessy is affiliated with the University of Northern Colorado in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology as well as Environmental Science. Within these broader fields, Mackessy has specialized in Genetics, Global and Planetary Change, Virology, Molecular Biology, and Microbiology.

The scientist's main research topics include Venomous Animal Envenomation and Studies, Amphibian and Reptile Biology, Rabies epidemiology and control, Biochemical and Structural Characterization, Antimicrobial Peptides and Activities, Insect and Pesticide Research, and Genetic diversity and population structure.

Mackessy has contributed to a number of recent publications, including:

  • De novo designed proteins neutralize lethal snake venom toxins (2025) published in Nature
  • Snake Recombination Landscapes Are Concentrated in Functional Regions despite PRDM9 (2020) published in Molecular Biology and Evolution
  • Snakes on a plain: biotic and abiotic factors determine venom compositional variation in a wide-ranging generalist rattlesnake (2023) published in BMC Biology
  • Convergent evolution of toxin resistance in animals (2022) published in Biological Reviews of the Cambridge Philosophical Society
  • The roles of balancing selection and recombination in the evolution of rattlesnake venom (2022) published in Nature Ecology & Evolution

Frequent co-authors of Mackessy include Todd A. Castoe, Cara F. Smith, Blair W. Perry, Drew R. Schield, and Anthony J. Saviola. Collaborations with these researchers have occurred in multiple publications, reflecting ongoing professional partnerships.

Mackessy's work has appeared in various publication venues with notable frequencies, including: Toxicon, bioRxiv (Cold Spring Harbor Laboratory), Genome Biology and Evolution, Nature, and Scientific Reports.

Best Publications

  • The Burmese python genome reveals the molecular basis for extreme adaptation in snakes

    Todd A. Castoe;Todd A. Castoe;A. P. Jason de Koning;A. P. Jason de Koning;Kathryn T. Hall;Daren C. Card

  • Venom ontogeny in the Pacific rattlesnakes Crotalus viridis helleri and C. v. oreganus

    Stephen P. Mackessy

  • An aqueous endpoint assay of snake venom phospholipase A2

    Matthew Holzer;Stephen P. Mackessy

  • Handbook of Venoms and Toxins of Reptiles

    Stephen P. Mackessy

  • Denmotoxin, a three-finger toxin from the colubrid snake Boiga dendrophila (Mangrove Catsnake) with bird-specific activity.

    Joanna Pawlak;Stephen P. Mackessy;Bryan G. Fry;Madhav Bhatia

  • Irditoxin, a novel covalently linked heterodimeric three-finger toxin with high taxon-specific neurotoxicity

    Joanna Pawlak;Stephen P. Mackessy;Nicole M. Sixberry;Enrico A. Stura

  • Venom of the Brown Treesnake, Boiga irregularis: ontogenetic shifts and taxa-specific toxicity.

    Stephen P. Mackessy;Nicole M. Sixberry;William H. Heyborne;Thomas Fritts

  • BIOCHEMISTRY AND PHARMACOLOGY OF COLUBRID SNAKE VENOMS

    Stephen P. Mackessy

  • Functional basis of a molecular adaptation: Prey-specific toxic effects of venom from Sistrurus rattlesnakes

    H. Lisle Gibbs;Stephen P. Mackessy

  • Venom proteomes of closely related Sistrurus rattlesnakes with divergent diets.

    Libia Sanz;H. Lisle Gibbs;Stephen P. Mackessy;Juan J. Calvete

  • Evolutionary trends in venom composition in the western rattlesnakes (Crotalus viridis sensu lato): toxicity vs. tenderizers.

    Stephen P. Mackessy

  • The origins and evolution of chromosomes, dosage compensation, and mechanisms underlying venom regulation in snakes.

    Drew R. Schield;Daren C. Card;Nicole R. Hales;Blair W. Perry

  • The venom gland transcriptome of the Desert Massasauga Rattlesnake (Sistrurus catenatus edwardsii): towards an understanding of venom composition among advanced snakes (Superfamily Colubroidea)

    Susanta Pahari;Stephen P Mackessy;R Manjunatha Kini;R Manjunatha Kini

  • Ontogenetic Variation in Venom Composition and Diet of Crotalus oreganus concolor: A Case of Venom Paedomorphosis?

    Stephen P. Mackessy;Kwame Williams;Kyle G. Ashton

  • Venom Composition in Rattlesnakes: Trends and Biological Significance

    Stephen P. Mackessy

  • The Field of Reptile Toxinology: Snakes, Lizards, and Their Venoms

    Stephen Mackessy

  • Characterization of venom (Duvernoy's secretion) from twelve species of colubrid snakes and partial sequence of four venom proteins.

    Robert E. Hill;Stephen P. Mackessy

  • Biochemical and pharmacological properties of a new thrombin-like serine protease (Russelobin) from the venom of Russell's Viper (Daboia russelii russelii) and assessment of its therapeutic potential

    Ashis K. Mukherjee;Stephen P. Mackessy

  • Identification and characterization of a taxon-specific three-finger toxin from the venom of the Green Vinesnake (Oxybelis fulgidus; family Colubridae).

    William H. Heyborne;Stephen P. Mackessy

  • Snake venom L-amino acid oxidases.

    Fung ShinYee;Tan NgetHong;S. P. Mackessy

Frequent Co-Authors

Todd A. Castoe
Todd A. Castoe The University of Texas at Arlington
Ashis K. Mukherjee
Ashis K. Mukherjee Tezpur University
R. Manjunatha Kini
R. Manjunatha Kini National University of Singapore
David D. Pollock
David D. Pollock University of Colorado Denver
Anne M. Bronikowski
Anne M. Bronikowski Iowa State University
Juan J. Calvete
Juan J. Calvete Spanish National Research Council
Wesley C. Warren
Wesley C. Warren University of Missouri
David A. Ray
David A. Ray Texas Tech University
Cédric Feschotte
Cédric Feschotte Cornell University
Patrick Minx
Patrick Minx Washington University in St. Louis

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