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Chemistry

D-Index
59
Citations
12226
World Ranking
10153
National Ranking
272

Research.com Recognitions

  • 1994 - Fellow of Alfred P. Sloan Foundation

Overview

Marco A. Ciufolini is affiliated with the University of British Columbia in Canada. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with specific contributions in subfields such as Molecular Biology, Organic Chemistry, Infectious Diseases, Biochemistry, and Pharmacology.

The main topics addressed in their body of work include:

  • RNA Interference and Gene Delivery
  • Chemical Synthesis and Analysis
  • Advanced biosensing and bioanalysis techniques
  • Click Chemistry and Applications
  • Clostridium difficile and Clostridium perfringens research
  • Renin-Angiotensin System Studies
  • Hormonal Regulation and Hypertension

Recent research papers authored or co-authored by Ciufolini include:

  • "Modular Lipid Nanoparticle Platform Technology for siRNA and Lipophilic Prodrug Delivery," 2021, Small
  • "A Route to Lipid ALC-0315: a Key Component of a COVID-19 mRNA Vaccine," 2022, Chemistry - A European Journal
  • "Quantitative Visualization of Lipid Nanoparticle Fusion as a Function of Formulation and Process Parameters," 2024, ACS Nano
  • "Diversity-oriented routes to thiopeptide antibiotics: total synthesis and biological evaluation of micrococcin P2," 2021, Organic & Biomolecular Chemistry
  • "From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia," 2023, Nature Communications

Frequent co-authors collaborating with Ciufolini include:

  • Hee-Jong Hwang
  • Pieter R. Cullis
  • Fariba Saadati
  • Pascal Bernatchez
  • Jayesh A. Kulkarni

Common venues where Ciufolini publishes are:

  • The Journal of Organic Chemistry
  • Small
  • ACS Nano
  • Chemistry - A European Journal
  • Blood

Among the recognitions received, Ciufolini was named a Fellow of the Alfred P. Sloan Foundation in 1994.

Best Publications

  • Rational design of cationic lipids for siRNA delivery

    Sean C Semple;Akin Akinc;Jianxin Chen;Ammen P Sandhu

  • The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

    Akin Akinc;Martin A. Maier;Muthiah Manoharan;Kevin Fitzgerald

  • Masitinib (AB1010), a Potent and Selective Tyrosine Kinase Inhibitor Targeting KIT

    Patrice Dubreuil;Sébastien Letard;Marco Ciufolini;Laurent Gros

  • Improved amino lipids and methods for the delivery of nucleic acids

    Michael J. Hope;Sean C. Semple;Jianxin Chen;Thomas D. Madden

  • Influence of Cationic Lipid Composition on Gene Silencing Properties of Lipid Nanoparticle Formulations of siRNA in Antigen-Presenting Cells

    Genc Basha;Tatiana I Novobrantseva;Nicole Rosin;Yuen Yi C Tam

  • Oxidation of oximes to nitrile oxides with hypervalent iodine reagents.

    Brian A. Mendelsohn;Shelley Lee;Simon Kim;Florian Teyssier

  • Improved compositions and methods for the delivery of nucleic acids

    Michael J. Hope;Sean C. Semple;Jianxin Chen;Thomas D. Madden

  • Chiral Hypervalent Iodine Reagents in Asymmetric Reactions

    Huan Liang;Huan Liang;Marco A. Ciufolini

  • Oxidative Amidation of Phenols through the Use of Hypervalent Iodine Reagents: Development and Applications

    Marco A. Ciufolini;Norbert A. Braun;Sylvain Canesi;Malika Ousmer

  • Total synthesis of tricyclic azaspirane derivatives of tyrosine: FR901483 and TAN1251C.

    Malika Ousmer;Norbert A. Braun;Claude Bavoux;Monique Perrin

  • New oxidative transformations of phenolic and indolic oxazolines: an avenue to useful azaspirocyclic building blocks.

    Norbert A. Braun;Malika Ousmer;Jonathan D. Bray;Denis Bouchu

  • Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo.

    Justin B. Lee;Kaixin Zhang;Yuen Yi C. Tam;Ying K. Tam

  • Fully Stereocontrolled Total Syntheses of (−)‐Cylindricine C and (−)‐2‐Epicylindricine C: A Departure in Sulfonamide Chemistry

    Sylvain Canesi;Denis Bouchu;Marco A. Ciufolini

  • Reductive cleavage of TROC groups under neutral conditions with cadmium-lead couple

    Qing Dong;C. Eric Anderson;Marco A. Ciufolini

  • 2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors

    Marco A. Ciufolini;Camille Wermuth;Bruno Giethlen;Alain Moussy

  • Iterative Oxazole Assembly via α‐Chloroglycinates: Total Synthesis of (−)‐Muscoride A

    Pierre-Yves Coqueron;Charles Didier;Marco A. Ciufolini

  • Intramolecular arylations of soft enolates catalyzed by zerovalent palladium

    Marco A. Ciufolini;Hong Bo Qi;Margaret E. Browne

  • A stereospecific route to aziridinomitosanes: the synthesis of novel mitomycin congeners

    Samuel Danishefsky;Ellen M. Berman;Marco Ciufolini;Sarah Jane Etheredge

  • Development of a weak-base docetaxel derivative that can be loaded into lipid nanoparticles.

    Igor V Zhigaltsev;Geoff Winters;Masuna Srinivasulu;Jason Crawford

  • Chemoenzymic synthesis of chiral furan derivatives: useful building blocks for optically active structures

    Dale G. Drueckhammer;Carlos F. Barbas;Kenji Nozaki;Chi Huey Wong

  • Synthesis of Spirolactams from tyrosine amides and related substances

    Norbert A. Braun;Norbert A. Braun;Marco A. Ciufolini;Marco A. Ciufolini;Karl Peters;Karl Peters;Eva-Maria Peter;Eva-Maria Peter

  • NITROGEN HETEROCYCLES FROM FURANS : THE AZA-ACHMATOWICZ REACTION

    Marco A. Ciufolini;Cynthia Y. W. Hermann;Qing Dong;Toshio Shimizu

Frequent Co-Authors

Pieter R. Cullis
Pieter R. Cullis University of British Columbia
Karl Peters
Karl Peters Max Planck Society
Don J. Mahuran
Don J. Mahuran University of Toronto
Marcel B. Bally
Marcel B. Bally University of British Columbia
Muthiah Manoharan
Muthiah Manoharan Alnylam Pharmaceuticals (United States)
Kenton H. Whitmire
Kenton H. Whitmire Rice University
Martin Maier
Martin Maier Alnylam Pharmaceuticals (United States)
Chi-Huey Wong
Chi-Huey Wong Scripps Research Institute
Eric Cundliffe
Eric Cundliffe University of Leicester
Dieter Brömme
Dieter Brömme University of British Columbia

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