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Maria João Saraiva

Maria João Saraiva

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Biology and Biochemistry
Portugal
2025

D-Index & Metrics

Biology and Biochemistry

D-Index
82
Citations
20822
World Ranking
3749
National Ranking
12

Research.com Recognitions

  • 2025 - Research.com Biology and Biochemistry in Portugal Leader Award

Overview

Maria João Saraiva is affiliated with the Instituto de Biologia Molecular e Celular in Portugal. Their research is primarily situated within the fields of medicine and biochemistry, genetics, and molecular biology. Saraiva's work extensively covers several specialized subfields, including molecular biology, surgery, genetics, cell biology, and gastroenterology.

The scientist's publication record highlights a focus on amyloidosis, with numerous studies addressing aspects of diagnosis, treatment, and outcomes related to this group of diseases. The main topics of their work also include gastrointestinal bleeding diagnosis and treatment, cellular transport and secretion mechanisms, coagulation and related disorders such as bradykinin and polyphosphates, colorectal cancer screening and detection, gastric cancer management and outcomes, and research into Alzheimer's disease treatments.

Frequent co-authors in Saraiva's research include Guilherme Macedo, Maria Rosário Almeida, João Afonso, Miguel Mascarenhas, and João Ferreira, reflecting collaboration across multiple projects and contributing to a diverse scientific network.

The venues where Saraiva regularly publishes include:

  • Amyloid
  • Endoscopy
  • Journal of Crohn's and Colitis
  • Atherosclerosis
  • bioRxiv (Cold Spring Harbor Laboratory)

Notable recent papers by Maria João Saraiva include:

  • "Amyloid nomenclature 2020: update and recommendations by the International Society of Amyloidosis (ISA) nomenclature committee," 2020, Amyloid
  • "Amyloid nomenclature 2022: update, novel proteins, and recommendations by the International Society of Amyloidosis (ISA) Nomenclature Committee," 2022, Amyloid
  • "A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells," 2021, Nature Communications
  • "Amyloid nomenclature 2024: update, novel proteins, and recommendations by the International Society of Amyloidosis (ISA) Nomenclature Committee," 2024, Amyloid
  • "Plasma neurofilament light chain: an early biomarker for hereditary ATTR amyloid polyneuropathy," 2020, Amyloid

Best Publications

  • Amyloid fibril proteins and amyloidosis: chemical identification and clinical classification International Society of Amyloidosis 2016 Nomenclature Guidelines.

    Jean D. Sipe;Merrill D. Benson;Joel N. Buxbaum;Shu Ichi Ikeda

  • Amyloid fibril protein in familial amyloidotic polyneuropathy, Portuguese type. Definition of molecular abnormality in transthyretin (prealbumin).

    M J Saraiva;S Birken;P P Costa;D S Goodman

  • Nomenclature 2014: Amyloid fibril proteins and clinical classification of the amyloidosis

    Jean D. Sipe;Merrill D. Benson;Joel N. Buxbaum;Shu Ichi Ikeda

  • Amyloid nomenclature 2018: recommendations by the International Society of Amyloidosis (ISA) nomenclature committee

    Merrill D Benson;Joel N Buxbaum;David S Eisenberg;Giampaolo Merlini

  • Amyloid: toward terminology clarification. Report from the Nomenclature Committee of the International Society of Amyloidosis.

    Per Westermark;Merrill D. Benson;Joel N. Buxbaum;Alan S. Cohen

  • Amyloid fibril protein nomenclature: 2010 recommendations from the nomenclature committee of the International Society of Amyloidosis

    Jean D. Sipe;Merrill D. Benson;Joel N. Buxbaum;Shu Ichi Ikeda

  • A primer of amyloid nomenclature

    Per Westermark;Merrill D. Benson;Joel N. Buxbaum;Alan S. Cohen

  • Deposition of transthyretin in early stages of familial amyloidotic polyneuropathy: evidence for toxicity of nonfibrillar aggregates.

    Mónica Mendes Sousa;Isabel Cardoso;Rui Fernandes;António Guimarães

  • Tetramer dissociation and monomer partial unfolding precedes protofibril formation in amyloidogenic transthyretin variants.

    Alexandre Quintas;Daniela C. Vaz;Isabel Cardoso;Maria João M. Saraiva

  • Amyloid fibril protein nomenclature: 2012 recommendations from the Nomenclature Committee of the International Society of Amyloidosis.

    Jean D. Sipe;Merrill D. Benson;Joel N. Buxbaum;Shu Ichi Ikeda

  • Amyloid nomenclature 2020: update and recommendations by the International Society of Amyloidosis (ISA) nomenclature committee.

    Merrill D Benson;Joel N Buxbaum;David S Eisenberg;Giampaolo Merlini

  • Familial amyloid polyneuropathy: receptor for advanced glycation end products-dependent triggering of neuronal inflammatory and apoptotic pathways.

    Mónica Mendes Sousa;Shirley ShiDu Yan;Rui Fernandes;António Guimarães

  • Transthyretin mutations in hyperthyroxinemia and amyloid diseases.

    Maria João Mascarenhas Saraiva

  • Amyloid fibril protein nomenclature -- 2002.

    Per Westermark;Merrill D. Benson;Joel N. Buxbaum;Alan S. Cohen

  • Interaction of the Receptor for Advanced Glycation End Products (RAGE) with Transthyretin Triggers Nuclear Transcription Factor kB (NF-kB) Activation

    Mónica Mendes Sousa;Shi Du Yan;David Stern;Maria João Saraiva;Maria João Saraiva

  • Doxycycline plus tauroursodeoxycholic acid for transthyretin amyloidosis: a phase II study.

    Laura Obici;Andrea Cortese;Alessandro Lozza;J. Lucchetti

  • The Tetrameric Protein Transthyretin Dissociates to a Non-native Monomer in Solution A NOVEL MODEL FOR AMYLOIDOGENESIS

    Alexandre Quintas;Maria João M. Saraiva;Rui M.M. Brito

  • Natural polyphenols inhibit different steps of the process of transthyretin (TTR) amyloid fibril formation.

    Nelson Ferreira;Maria João Saraiva;Maria João Saraiva;Maria Rosário Almeida

  • Synergy of combined Doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: studies in FAP mouse models

    Isabel Cardoso;Isabel Cardoso;Diana Martins;Tania Ribeiro;Giampaolo Merlini

  • Neurodegeneration in familial amyloid polyneuropathy: from pathology to molecular signaling.

    Mónica Mendes Sousa;Maria João Saraiva;Maria João Saraiva

Frequent Co-Authors

Giampaolo Merlini
Giampaolo Merlini University of Pavia
DeWitt S. Goodman
DeWitt S. Goodman Columbia University
Merrill D. Benson
Merrill D. Benson Indiana University
Jean D. Sipe
Jean D. Sipe Boston University
Per Westermark
Per Westermark Uppsala University
Max E. Gottesman
Max E. Gottesman Columbia University Medical Center
William S. Blaner
William S. Blaner Columbia University
Alan S. Cohen
Alan S. Cohen Boston University
Ken Ichi Yamamura
Ken Ichi Yamamura Kumamoto University
Hiroyuki Sasaki
Hiroyuki Sasaki Kyushu University

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