Fabrizio Chiti

Overview

Best Publications

• Protein Misfolding, Functional Amyloid, and Human Disease

  Fabrizio Chiti;Christopher M. Dobson

  7672
  Citations

• Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases.

  Monica Bucciantini;Elisa Giannoni;Fabrizio Chiti;Fabrizio Chiti;Fabiana Baroni

  3005
  Citations

• Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade

  Fabrizio Chiti;Christopher M. Dobson

  2665
  Citations

• Designing conditions for in vitro formation of amyloid protofilaments and fibrils

  Fabrizio Chiti;Paul Webster;Niccolò Taddei;Anne Clark

  1379
  Citations

• Rationalization of the effects of mutations on peptide and protein aggregation rates.

  Fabrizio Chiti;Massimo Stefani;Niccolò Taddei;Giampietro Ramponi

  1307
  Citations

• Amyloid formation by globular proteins under native conditions

  Fabrizio Chiti;Christopher M Dobson

  975
  Citations

• Prediction of "aggregation-prone" and "aggregation-susceptible" regions in proteins associated with neurodegenerative diseases.

  Amol P. Pawar;Kateri F. DuBay;Jesús Zurdo;Fabrizio Chiti

  726
  Citations

• Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers

  Giuliana Fusco;Giuliana Fusco;Serene W. Chen;Serene W. Chen;Philip T. F. Williamson;Roberta Cascella

  675
  Citations

• A causative link between the structure of aberrant protein oligomers and their toxicity

  Silvia Campioni;Benedetta Mannini;Mariagioia Zampagni;Anna Pensalfini;Anna Pensalfini

  614
  Citations

• Kinetic partitioning of protein folding and aggregation.

  Fabrizio Chiti;Niccolò Taddei;Fabiana Baroni;Cristina Capanni

  513
  Citations

• Prediction of Aggregation-Prone Regions in Structured Proteins

  Gian Gaetano Tartaglia;Amol P. Pawar;Silvia Campioni;Christopher M. Dobson

  506
  Citations

• Prefibrillar amyloid protein aggregates share common features of cytotoxicity.

  Monica Bucciantini;Giulia Calloni;Fabrizio Chiti;Lucia Formigli

  467
  Citations

• Prediction of the absolute aggregation rates of amyloidogenic polypeptide chains.

  Kateri F. DuBay;Amol P. Pawar;Fabrizio Chiti;Jesús Zurdo

  383
  Citations

• Mutational analysis of acylphosphatase suggests the importance of topology and contact order in protein folding.

  Fabrizio Chiti;Niccolò Taddei;Paul M. White;Monica Bucciantini

  353
  Citations

• Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases

  Fabrizio Chiti;Martino Calamai;Niccolò Taddei;Massimo Stefani

  352
  Citations

• Protein misfolded oligomers: experimental approaches, mechanism of formation, and structure-toxicity relationships.

  Francesco Bemporad;Fabrizio Chiti

  311
  Citations

• Prefibrillar amyloid aggregates could be generic toxins in higher organisms

  Serena Baglioni;Fiorella Casamenti;Monica Bucciantini;Leila M. Luheshi

  310
  Citations

• Short amino acid stretches can mediate amyloid formation in globular proteins: The Src homology 3 (SH3) case

  Salvador Ventura;Jesús Zurdo;Saravanakumar Narayanan;Matilde Parreño

  305
  Citations

• Mutational analysis of the propensity for amyloid formation by a globular protein.

  Fabrizio Chiti;Niccolò Taddei;Monica Bucciantini;Paul White

  298
  Citations

• Prevention of amyloid‐like aggregation as a driving force of protein evolution

  Elodie Monsellier;Fabrizio Chiti

  283
  Citations