World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
16972
World Ranking
7025
National Ranking
538

Overview

Alan J. Knox is affiliated with the University of Nottingham in the United Kingdom and has contributed extensively to research in medicine, with a particular focus on pulmonary and respiratory medicine. Their work spans fields including biochemistry, genetics, molecular biology, physiology, cardiology, and pediatrics, reflecting a multidisciplinary approach to respiratory health and disease.

Recent research publications by Alan J. Knox include studies on severe asthma characterized by type 2 inflammation, lung function decline in cystic fibrosis, medication adherence in severe asthma, airway and parenchymal lung fibroblasts methylation, and bacterial quorum sensing molecules as biomarkers in cystic fibrosis. Notable papers are:

  • Urinary Leukotriene E4and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study, 2020, American Journal of Respiratory and Critical Care Medicine
  • Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis, 2022, Journal of Medical Microbiology
  • Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort, 2021, CHEST Journal
  • TWIST1 DNA methylation is a cell marker of airway and parenchymal lung fibroblasts that are differentially methylated in asthma, 2020, Clinical Epigenetics
  • Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis, 2021, Journal of Cystic Fibrosis

Alan J. Knox frequently collaborates with several researchers, with five joint publications each alongside Nur Masirah M. Zain, Andrew Fogarty, E.F. Nash, J.L. Whitehouse, and Alan R Smyth.

The scientist's work appears prominently in several publication venues, including:

  • Journal of Cystic Fibrosis
  • Journal of Medical Microbiology
  • American Journal of Respiratory and Critical Care Medicine
  • CHEST Journal
  • Clinical Epigenetics

Core research topics covered by Alan J. Knox include:

  • Cystic Fibrosis Research Advances
  • Asthma and respiratory diseases
  • Bacterial biofilms and quorum sensing
  • Inhalation and Respiratory Drug Delivery
  • Epigenetics and DNA Methylation
  • Neonatal Respiratory Health Research
  • Respiratory and Cough-Related Research

Best Publications

  • A promoter-level mammalian expression atlas

    Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie

  • Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort

    Dominick E. Shaw;Ana R. Sousa;Stephen J. Fowler;Louise J. Fleming

  • Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease.

    Coen H. Wiegman;Charalambos Michaeloudes;Gulammehdi Haji;Priyanka Narang

  • Guidelines for the management of hospital-acquired pneumonia in the UK: Report of the Working Party on Hospital-Acquired Pneumonia of the British Society for Antimicrobial Chemotherapy

    R. G. Masterton;A. Galloway;G. French;M. Street

  • REBOUND INCREASE IN BRONCHIAL RESPONSIVENESS AFTER TREATMENT WITH INHALED TERBUTALINE

    A.S. Vathenen;B.G. Higgins;A.J. Knox;J.R. Britton

  • Dietary magnesium, lung function, wheezing, and airway hyperreactivity in a random adult population sample

    J Britton;I Pavord;K Richards;A Wisniewski

  • Dietary antioxidant vitamin intake and lung function in the general population.

    J R Britton;I D Pavord;K A Richards;A J Knox

  • FANTOM5 CAGE profiles of human and mouse samples

    Shuhei Noguchi;Takahiro Arakawa;Shiro Fukuda;Masaaki Furuno

  • Reproducibility of walking test results in chronic obstructive airways disease.

    A. J. Knox;J. F. J. Morrison;M. F. Muers

  • U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics

    Diane Lefaudeux;Bertrand De Meulder;Matthew J. Loza;Nancy Peffer

  • Synergistic Inhibition by β2-Agonists and Corticosteroids on Tumor Necrosis Factor- α –Induced Interleukin-8 Release from Cultured Human Airway Smooth-Muscle Cells

    Linhua Pang;Alan J. Knox

  • Synthetic functions of airway smooth muscle in asthma.

    Simon R Johnson;Alan J Knox

  • Time course of change in bronchial reactivity with an inhaled corticosteroid in asthma.

    A S Vathenen;A J Knox;A Wisniewski;A E Tattersfield

  • Lysophosphatidic Acid Induces αvβ6 Integrin-Mediated TGF-β Activation via the LPA2 Receptor and the Small G Protein Gαq

    Ming Yan Xu;Joanne Porte;Alan J. Knox;Paul H. Weinreb

  • Once versus three-times daily regimens of tobramycin treatment for pulmonary exacerbations of cystic fibrosis--the TOPIC study: a randomised controlled trial.

    Alan Smyth;Kelvin H-V Tan;Pauline Hyman-Taylor;Michael Mulheran

  • Synthetic responses in airway smooth muscle

    Peter H Howarth;Alan J Knox;Yassine Amrani;Omar Tliba

  • Effect of interleukin‐1β, tumour necrosis factor‐α and interferon‐γ on the induction of cyclo‐oxygenase‐2 in cultured human airway smooth muscle cells

    Linhua Pang;Alan J. Knox

  • Direct detection of N-acylhomoserine lactones in cystic fibrosis sputum

    Barry Middleton;Helen C Rodgers;Miguel Cámara;Alan J Knox

  • Defective histone acetylation is responsible for the diminished expression of cyclooxygenase 2 in idiopathic pulmonary fibrosis

    William R. Coward;Keiria Watts;Carol A. Feghali-Bostwick;Alan Knox

  • TNFα and IFNγ Synergistically Enhance Transcriptional Activation of CXCL10 in Human Airway Smooth Muscle Cells via STAT-1, NF-κB, and the Transcriptional Coactivator CREB-binding Protein

    Deborah L. Clarke;Rachel L. Clifford;Sarawut Jindarat;David Proud

Frequent Co-Authors

John Britton
John Britton University of Nottingham
Anne E. Tattersfield
Anne E. Tattersfield University of Nottingham
Ian D. Pavord
Ian D. Pavord University of Oxford
Miguel Cámara
Miguel Cámara University of Nottingham
Paul Williams
Paul Williams University of Nottingham
Christopher E. Brightling
Christopher E. Brightling University of Leicester
David A. Barrett
David A. Barrett University of Nottingham
Sarah Lewis
Sarah Lewis University of Nottingham
Carol Feghali-Bostwick
Carol Feghali-Bostwick Medical University of South Carolina
Juha Kere
Juha Kere Karolinska Institute

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students passionate about Biology and Biochemistry, a variety of flexible online degrees and certifications can open doors to rewarding healthcare careers. Many professionals pursue additional training that blends life sciences with hands-on patient care.

Diagnostic imaging is a growing field. If you're interested, consider earning an ultrasound tech certification online to begin a career in sonography. Similarly, rad tech online programs provide foundational knowledge in radiologic technology for those aiming to work with X-rays and other imaging equipment.

Nutrition science is another popular pathway for biology graduates. For advanced roles in clinical and community nutrition, consider accredited registered dietitian masters programs.

If you’re looking for a quicker path to clinical work, online medical assisting school can prepare you for vital support roles in healthcare practices. Exploring these online programs allows you to connect your biology background with diverse, in-demand careers.

Best Scientists Citing Alan J. Knox

Trending Scientists

Recently Published Articles