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D-Index & Metrics

Microbiology

D-Index
125
Citations
50964
World Ranking
108
National Ranking
12

Overview

Paul Williams is affiliated with the University of Nottingham in the United Kingdom and has a significant body of research in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine.

Their research encompasses several subfields, including Molecular Biology, Biomedical Engineering, Pulmonary and Respiratory Medicine, Molecular Medicine, and Microbiology. The main topics covered by their work include bacterial biofilms and quorum sensing, antibiotic resistance in bacteria, antimicrobial peptides and activities, bacterial genetics and biotechnology, cystic fibrosis research advances, 3D printing in biomedical research, and bacterial identification and susceptibility testing.

Paul Williams has published in various reputable venues throughout their career. The most frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), Microbiology, Journal of Cystic Fibrosis, Advanced Science, and Blood.

Notable recent papers are:

  • Immune Modulation by Design: Using Topography to Control Human Monocyte Attachment and Macrophage Differentiation, 2020, Advanced Science
  • Cryo-OrbiSIMS for 3D Molecular Imaging of a Bacterial Biofilm in Its Native State, 2020, Analytical Chemistry
  • AbaM Regulates Quorum Sensing, Biofilm Formation, and Virulence in Acinetobacter baumannii, 2021, Journal of Bacteriology
  • Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR, 2020, European Journal of Medicinal Chemistry
  • Whole-genome sequencing and gene sharing network analysis powered by machine learning identifies antibiotic resistance sharing between animals, humans and environment in livestock farming, 2022, PLoS Computational Biology

Paul Williams collaborates frequently with several coauthors, including Morgan R. Alexander, Jean-Frédéric Dubern, Miguel Cámara, Andrew L. Hook, and Nigel Halliday.

Best Publications

  • Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones

    Kay H. McClean;Michael K. Winson;Leigh Fish;Adrian Taylor

  • Look who's talking: communication and quorum sensing in the bacterial world

    Paul Williams;Klaus Winzer;Weng C Chan;Miguel Cámara

  • A hierarchical quorum-sensing cascade in Pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationary-phase sigma factor RpoS

    A. Latifi;M. Foglino;K. Tanaka;P. Williams

  • Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules

    Paul Williams;Miguel Cámara

  • Quorum sensing, communication and cross-kingdom signalling in the bacterial world

    Paul Williams

  • Quorum-sensing cross talk: isolation and chemical characterization of cyclic dipeptides from Pseudomonas aeruginosa and other gram-negative bacteria.

    Matthew T.G. Holden;Siri Ram Chhabra;Rocky De Nys;Paul Stead

  • Construction and analysis of luxCDABE-based plasmid sensors for investigating N-acyl homoserine lactone-mediated quorum sensing

    Michael K Winson;Simon Swift;Leigh Fish;John P Throup

  • Quinolones: from antibiotics to autoinducers

    Stephan Heeb;Matthew P. Fletcher;Siri Ram Chhabra;Stephen P. Diggle

  • Cell–cell signaling in Xanthomonas campestris involves an HD-GYP domain protein that functions in cyclic di-GMP turnover

    Robert P. Ryan;Yvonne Fouhy;Jean F. Lucey;Lisa C. Crossman

  • A novel regulatory system required for pathogenicity of Xanthomonas campestris is mediated by a small diffusible signal molecule

    C. E. Barber;J. L. Tang;J. X. Feng;M. Q. Pan

  • Multiple homologues of LuxR and LuxI control expression of virulence determinants and secondary metabolites through quorum sensing in Pseudomonas aeruginosa PAO1

    Amel Latifi;Michael K. Winson;Maryline Foglino;Barrie W. Bycroft

  • The Pseudomonas aeruginosa 4-Quinolone Signal Molecules HHQ and PQS Play Multifunctional Roles in Quorum Sensing and Iron Entrapment

    Stephen P. Diggle;Sandra Matthijs;Victoria J. Wright;Matthew P. Fletcher

  • N-Acylhomoserine Lactones Undergo Lactonolysis in a pH-, Temperature-, and Acyl Chain Length-Dependent Manner during Growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa

    Edwin A. Yates;Bodo Philipp;Catherine Buckley;Steve Atkinson

  • The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density‐dependency of the quorum sensing hierarchy, regulates rhl‐dependent genes at the onset of stationary phase and can be produced in the absence of LasR

    Stephen P. Diggle;Klaus Winzer;Siri Ram Chhabra;Kathryn E. Worrall

  • The Pseudomonas aeruginosa Quorum-Sensing Signal Molecule N-(3-Oxododecanoyl)-l-Homoserine Lactone Has Immunomodulatory Activity

    Gary Telford;D. Wheeler;Paul Williams;P. T. Tomkins

  • Quorum sensing in Aeromonas hydrophila and Aeromonas salmonicida: identification of the LuxRI homologs AhyRI and AsaRI and their cognate N-acylhomoserine lactone signal molecules.

    Simon Swift;Andrey V. Karlyshev;Leigh Fish;Emma L. Durant

  • The bacterial 'enigma': cracking the code of cell-cell communication

    G. P. C. Salmond;B. W. Bycroft;G. S. A. B. Stewart;P. Williams

  • Quorum sensing and social networking in the microbial world

    Steve Atkinson;Paul Williams

  • Involvement of N‐acyl‐l‐homoserine lactone autoinducers in controlling the multicellular behaviour of Serratia liquefaciens

    Leo Eberl;Michael K. Winson;Claus Sternberg;Gordon S. A. B. Stewart

  • A cell-cell communication signal integrates quorum sensing and stress response

    Jasmine Lee;Jien Wu;Yinyue Deng;Jing Wang

  • THE INFLUENCE OF ENVIRONMENT ON ENVELOPE PROPERTIES AFFECTING SURVIVAL OF BACTERIA IN INFECTIONS

    Michael R. W. Brown;Paul Williams

Frequent Co-Authors

Miguel Cámara
Miguel Cámara University of Nottingham
Barrie W. Bycroft
Barrie W. Bycroft University of Nottingham
Siri Ram Chhabra
Siri Ram Chhabra University of Nottingham
Morgan R. Alexander
Morgan R. Alexander University of Nottingham
Gordon S. A. B. Stewart
Gordon S. A. B. Stewart University of Nottingham
Stephen P. Diggle
Stephen P. Diggle Georgia Institute of Technology
Klaus Winzer
Klaus Winzer University of Nottingham
David A. Barrett
David A. Barrett University of Nottingham
Martyn C. Davies
Martyn C. Davies University of Nottingham
Alan J. Knox
Alan J. Knox University of Nottingham

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