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Daniel L.A. van den Hove

Daniel L.A. van den Hove

D-Index & Metrics

Neuroscience

D-Index
43
Citations
7197
World Ranking
7401
National Ranking
205

Overview

Daniel L.A. van den Hove is affiliated with Maastricht University in the Netherlands. Their research focuses primarily on areas within biochemistry, genetics, and molecular biology, with significant contributions in medicine. They have a particular emphasis on molecular biology, psychiatry and mental health, physiology, genetics, and behavioral neuroscience.

The main topics covered in their work include:

  • Epigenetics and DNA Methylation
  • Stress Responses and Cortisol
  • Phosphodiesterase function and regulation
  • Cholinesterase and Neurodegenerative Diseases
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's disease research and treatments
  • Dementia and Cognitive Impairment Research

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurobiology of Aging
  • Cellular and Molecular Life Sciences
  • Current Biology
  • Stem Cell Research

Some recent papers authored in part by van den Hove are:

  • "A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex" (2021, Nature Communications)
  • "An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene" (2020, Neurobiology of Aging)
  • "The Molecular Biology of Phosphodiesterase 4 Enzymes as Pharmacological Targets: An Interplay of Isoforms, Conformational States, and Inhibitors" (2021, Pharmacological Reviews)
  • "DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation" (2021, Cellular and Molecular Life Sciences)
  • "How the COVID-19 pandemic highlights the necessity of animal research" (2020, Current Biology)

Van den Hove collaborates frequently with other researchers, with frequent co-authors including:

  • Tim Vanmierlo
  • Jos Prickaerts
  • Ehsan Pishva
  • Melissa Schepers
  • Ben Rombaut

Best Publications

  • Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients.

    Leonidas Chouliaras;Diego Mastroeni;Diego Mastroeni;Elaine Delvaux;Andrew Grover

  • The epigenetics of aging and neurodegeneration.

    Roy Lardenoije;Artemis Iatrou;Gunter Kenis;Konstantinos Kompotis

  • Epigenetic regulation in the pathophysiology of Alzheimer's disease.

    Leonidas Chouliaras;Bart P.F. Rutten;Gunter Kenis;Odette Peerbooms

  • Neurotrophic factors and neuroplasticity pathways in the pathophysiology and treatment of depression

    Marion J. F. Levy;Marion J. F. Levy;Marion J. F. Levy;Fabien Boulle;Fabien Boulle;Fabien Boulle;Harry W. Steinbusch;Harry W. Steinbusch;Daniël L. A. van den Hove;Daniël L. A. van den Hove;Daniël L. A. van den Hove

  • Defeat stress in rodents: From behavior to molecules.

    Caroline Hammels;Ehsan Pishva;Jochen De Vry;Daniel L A van den Hove

  • Fluoxetine during development reverses the effects of prenatal stress on depressive-like behavior and hippocampal neurogenesis in adolescence.

    Ine Rayen;Daniël L. van den Hove;Jos Prickaerts;Harry W. Steinbusch

  • Targeting brain serotonin synthesis: insights into neurodevelopmental disorders with long-term outcomes related to negative emotionality, aggression and antisocial behaviour

    Klaus-Peter Lesch;Klaus-Peter Lesch;Naozumi Araragi;Jonas Waider;Daniel van den Hove;Daniel van den Hove

  • Major depression, cognitive dysfunction and Alzheimer's disease: is there a link?

    Annerieke S.R. Sierksma;Daniel L.A. van den Hove;Daniel L.A. van den Hove;Harry W.M. Steinbusch;Harry W.M. Steinbusch;Jos Prickaerts;Jos Prickaerts

  • A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.

    Rebecca G. Smith;Ehsan Pishva;Ehsan Pishva;Gemma Shireby;Adam R. Smith

  • Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder

    B. P.F. Rutten;E. Vermetten;E. Vermetten;E. Vermetten;C. H. Vinkers;G. Ursini

  • Prenatal Restraint Stress and Long-Term Affective Consequences

    Unknown

  • Epigenetically regulated microRNAs in Alzheimer's disease

    Daniel L. Van den Hove;Daniel L. Van den Hove;Konstantinos Kompotis;Roy Lardenoije;Gunter Kenis

  • Alzheimer’s disease-associated (hydroxy)methylomic changes in the brain and blood

    Roy Lardenoije;Roy Lardenoije;Janou A. Y. Roubroeks;Janou A. Y. Roubroeks;Ehsan Pishva;Ehsan Pishva;Markus Leber

  • Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease

    Adam R. Smith;Rebecca G. Smith;Ehsan Pishva;Ehsan Pishva;Eilis Hannon

  • Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice

    Lise Gutknecht;Lise Gutknecht;Sandy Popp;Jonas Waider;Frank M. J. Sommerlandt

  • Chronic fluoxetine treatment and maternal adversity differentially alter neurobehavioral outcomes in the rat dam.

    Jodi L. Pawluski;Thierry D. Charlier;Marianne Fillet;Virginie Houbart

  • From OPC to Oligodendrocyte: An Epigenetic Journey.

    Assia Tiane;Assia Tiane;Melissa Schepers;Melissa Schepers;Ben Rombaut;Ben Rombaut;Raymond Hupperts

  • Prenatal stress and subsequent exposure to chronic mild stress influence dendritic spine density and morphology in the rat medial prefrontal cortex.

    Kimmo A Michelsen;Kimmo A Michelsen;Kimmo A Michelsen;Daniël L A van den Hove;Daniël L A van den Hove;Christoph Schmitz;Christoph Schmitz;Olivier Segers;Olivier Segers

  • Epigenetics and DNA methylomic profiling in Alzheimer's disease and other neurodegenerative diseases.

    Janou A. Y. Roubroeks;Rebecca G. Smith;Daniel L. A. van den Hove;Daniel L. A. van den Hove;Katie Lunnon

  • Behavioral and neurobiological effects of prenatal stress exposure in male and female APPswe/PS1dE9 mice.

    Annerieke S.R. Sierksma;Jos Prickaerts;Leonidas Chouliaras;Somayeh Rostamian

  • Differential effects of prenatal stress in 5-Htt deficient mice: towards molecular mechanisms of gene × environment interactions.

    Daniel Louis Albert van den Hove;Daniel Louis Albert van den Hove;Sissi Brigitte Jakob;Karla-Gerlinde Schraut;Gunter Kenis

  • Gestational stress leads to depressive-like behavioural and immunological changes in the rat.

    Siobhain M. O’Mahony;Aye-Mu Myint;Daniel van den Hove;Lieve Desbonnet

Frequent Co-Authors

Gunter Kenis
Gunter Kenis Maastricht University
Bart P. F. Rutten
Bart P. F. Rutten Maastricht University Medical Centre
Harry W.M. Steinbusch
Harry W.M. Steinbusch Maastricht University
Jonathan Mill
Jonathan Mill University of Exeter
Jodi L. Pawluski
Jodi L. Pawluski University of Rennes
Paul D. Coleman
Paul D. Coleman Arizona State University
Marco P. Boks
Marco P. Boks University of Amsterdam
Koen Schruers
Koen Schruers Maastricht University
Tatyana Strekalova
Tatyana Strekalova Maastricht University
Judith R. Homberg
Judith R. Homberg Radboud University

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