D-Index & Metrics Best Publications
Medicine
Switzerland
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 99 Citations 33,189 264 World Ranking 439 National Ranking 12
Medicine D-index 102 Citations 35,557 296 World Ranking 4546 National Ranking 61

Research.com Recognitions

Awards & Achievements

2023 - Research.com Medicine in Switzerland Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Cytokine

The scientist’s investigation covers issues in Immunology, Tumor necrosis factor alpha, Cell biology, Molecular biology and Apoptosis. His Immunology study combines topics in areas such as Meningitis and Cerebrospinal fluid. The Tumor necrosis factor alpha study combines topics in areas such as Receptor, Central nervous system and Cytokine.

His Cell biology research integrates issues from Immune system and Microglia. His studies deal with areas such as Interleukin 3, Cell culture and IL1A as well as Molecular biology. His studies in Apoptosis integrate themes in fields like Cytotoxic T cell, Glioma and Immunotherapy.

His most cited work include:

  • Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-xL (282 citations)
  • TNF-α suppresses the expression of clock genes by interfering with E-box-mediated transcription (277 citations)
  • IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. (264 citations)

What are the main themes of his work throughout his whole career to date?

Immunology, Tumor necrosis factor alpha, Molecular biology, Cytokine and Cell biology are his primary areas of study. His research investigates the connection between Immunology and topics such as Meningitis that intersect with problems in Cerebrospinal fluid. The various areas that he examines in his Tumor necrosis factor alpha study include Interleukin, Receptor and Cancer research.

The study incorporates disciplines such as Fas ligand, Gene expression, Cycloheximide, Transcription factor and Fas receptor in addition to Molecular biology. The concepts of his Cytokine study are interwoven with issues in Multiple sclerosis, Antibody and Microglia. His biological study spans a wide range of topics, including Apoptosis and Cell.

He most often published in these fields:

  • Immunology (49.22%)
  • Tumor necrosis factor alpha (20.73%)
  • Molecular biology (20.21%)

What were the highlights of his more recent work (between 2009-2020)?

  • Immunology (49.22%)
  • Tumor necrosis factor alpha (20.73%)
  • Cytokine (19.69%)

In recent papers he was focusing on the following fields of study:

Adriano Fontana focuses on Immunology, Tumor necrosis factor alpha, Cytokine, Internal medicine and CLOCK. His research on Immunology frequently connects to adjacent areas such as CD40. His Tumor necrosis factor alpha research incorporates themes from Hippocampal formation, Neuroscience, Interleukin and Inflammation.

His study in Cell biology extends to Cytokine with its themes. His work in Internal medicine addresses subjects such as Endocrinology, which are connected to disciplines such as Sleep in non-human animals and Receptor. Adriano Fontana has included themes like CIRBP, RNA-binding protein, Regulation of gene expression and Molecular biology in his CLOCK study.

Between 2009 and 2020, his most popular works were:

  • Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling (149 citations)
  • The NLRP3 Inflammasome Contributes to Brain Injury in Pneumococcal Meningitis and Is Activated through ATP-Dependent Lysosomal Cathepsin B Release (149 citations)
  • MHC class II–restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell–mediated autoimmunity (116 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cytokine

His primary areas of investigation include Immunology, Multiple sclerosis, Cytokine, Antigen and Immune system. Adriano Fontana studies Immunology, focusing on Microglia in particular. His studies deal with areas such as Tumor necrosis factor alpha and Central nervous system as well as Multiple sclerosis.

His work carried out in the field of Tumor necrosis factor alpha brings together such families of science as Dentate gyrus, Hippocampal formation, Autoimmune encephalitis, Astrocyte and Signal transduction. His research in Antigen tackles topics such as T cell which are related to areas like Priming and Experimental autoimmune encephalomyelitis. His studies in Immune system integrate themes in fields like Myeloid, Encephalomyelitis, Cell adhesion molecule and Lymphocyte.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Melanoma Cell Expression of Fas(Apo-1/CD95) Ligand: Implications for Tumor Immune Escape

M. Hahne;D. Rimoldi;M. Schröter;P. Romero.
Science (1996)

1713 Citations

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

Laura Codarri;Gabor Gyülvészi;Vinko Tosevski;Lysann Hesske.
Nature Immunology (2011)

1252 Citations

Conversion of Membrane-bound Fas(CD95) Ligand to Its Soluble Form Is Associated with Downregulation of Its Proapoptotic Activity and Loss of Liver Toxicity

Pascal Schneider;Nils Holler;Jean Luc Bodmer;Michael Hahne.
Journal of Experimental Medicine (1998)

970 Citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines.

Adriano Fontana;Walter Fierz;Hartmut Wekerle.
Nature (1984)

968 Citations

Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells.

A Fontana;F Kristensen;R Dubs;D Gemsa.
Journal of Immunology (1982)

939 Citations

On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases.

Karl Frei;Ursula V. Malipiero;Thomas P. Leist;Rolf M. Zinkernagel.
European Journal of Immunology (1989)

834 Citations

Increased Number of Islet-Associated Macrophages in Type 2 Diabetes

Jan A. Ehses;Aurel Perren;Elisabeth Eppler;Pascale Ribaux.
Diabetes (2007)

785 Citations

Antigen presentation and tumor cytotoxicity by interferon-γ-treated microglial cells

Karl Frei;Christine Siepl;Peter Groscurth;Stefan Bodmer.
European Journal of Immunology (1987)

760 Citations

Prevention of Islet Allograft Rejection with Engineered Myoblasts Expressing FasL in Mice

Henry T. Lau;Ming Yu;Adriano Fontana;Christian J. Stoeckert.
Science (1996)

586 Citations

Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation.

W Fierz;B Endler;K Reske;H Wekerle.
Journal of Immunology (1985)

556 Citations

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