Adriano Fontana

What is he best known for?

The fields of study he is best known for:

• Gene
• Immune system
• Cytokine

The scientist’s investigation covers issues in Immunology, Tumor necrosis factor alpha, Cell biology, Molecular biology and Apoptosis. His Immunology study combines topics in areas such as Meningitis and Cerebrospinal fluid. The Tumor necrosis factor alpha study combines topics in areas such as Receptor, Central nervous system and Cytokine.

His Cell biology research integrates issues from Immune system and Microglia. His studies deal with areas such as Interleukin 3, Cell culture and IL1A as well as Molecular biology. His studies in Apoptosis integrate themes in fields like Cytotoxic T cell, Glioma and Immunotherapy.

His most cited work include:

• Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-xL (282 citations)
• TNF-α suppresses the expression of clock genes by interfering with E-box-mediated transcription (277 citations)
• IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. (264 citations)

What are the main themes of his work throughout his whole career to date?

Immunology, Tumor necrosis factor alpha, Molecular biology, Cytokine and Cell biology are his primary areas of study. His research investigates the connection between Immunology and topics such as Meningitis that intersect with problems in Cerebrospinal fluid. The various areas that he examines in his Tumor necrosis factor alpha study include Interleukin, Receptor and Cancer research.

The study incorporates disciplines such as Fas ligand, Gene expression, Cycloheximide, Transcription factor and Fas receptor in addition to Molecular biology. The concepts of his Cytokine study are interwoven with issues in Multiple sclerosis, Antibody and Microglia. His biological study spans a wide range of topics, including Apoptosis and Cell.

He most often published in these fields:

• Immunology (49.22%)
• Tumor necrosis factor alpha (20.73%)
• Molecular biology (20.21%)

What were the highlights of his more recent work (between 2009-2020)?

• Immunology (49.22%)
• Tumor necrosis factor alpha (20.73%)
• Cytokine (19.69%)

In recent papers he was focusing on the following fields of study:

Adriano Fontana focuses on Immunology, Tumor necrosis factor alpha, Cytokine, Internal medicine and CLOCK. His research on Immunology frequently connects to adjacent areas such as CD40. His Tumor necrosis factor alpha research incorporates themes from Hippocampal formation, Neuroscience, Interleukin and Inflammation.

His study in Cell biology extends to Cytokine with its themes. His work in Internal medicine addresses subjects such as Endocrinology, which are connected to disciplines such as Sleep in non-human animals and Receptor. Adriano Fontana has included themes like CIRBP, RNA-binding protein, Regulation of gene expression and Molecular biology in his CLOCK study.

Between 2009 and 2020, his most popular works were:

• Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling (149 citations)
• The NLRP3 Inflammasome Contributes to Brain Injury in Pneumococcal Meningitis and Is Activated through ATP-Dependent Lysosomal Cathepsin B Release (149 citations)
• MHC class II–restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell–mediated autoimmunity (116 citations)

In his most recent research, the most cited papers focused on:

• Gene
• Immune system
• Cytokine

His primary areas of investigation include Immunology, Multiple sclerosis, Cytokine, Antigen and Immune system. Adriano Fontana studies Immunology, focusing on Microglia in particular. His studies deal with areas such as Tumor necrosis factor alpha and Central nervous system as well as Multiple sclerosis.

His work carried out in the field of Tumor necrosis factor alpha brings together such families of science as Dentate gyrus, Hippocampal formation, Autoimmune encephalitis, Astrocyte and Signal transduction. His research in Antigen tackles topics such as T cell which are related to areas like Priming and Experimental autoimmune encephalomyelitis. His studies in Immune system integrate themes in fields like Myeloid, Encephalomyelitis, Cell adhesion molecule and Lymphocyte.