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Overview

David Simon is affiliated with Beth Israel Deaconess Medical Center in the United States. Their research primarily focuses on Medicine, with a concentration on Neurology and related subfields such as Cellular and Molecular Neuroscience, Physiology, Molecular Biology, and Cognitive Neuroscience.

The main topics covered in Simon's work include Parkinson's Disease Mechanisms and Treatments, Nuclear Receptors and Signaling, Autism Spectrum Disorder Research, Neurological Disorders and Treatments, Cerebral Palsy and Movement Disorders, RNA Regulation and Disease, and Chronic Myeloid Leukemia Treatments.

Frequent publication venues for Simon include Movement Disorders, Neurology, bioRxiv (Cold Spring Harbor Laboratory), JAMA Neurology, and Ageing Research Reviews.

Key recent papers include:

  • Trial of Cinpanemab in Early Parkinson's Disease, 2022, New England Journal of Medicine
  • Effect of Urate-Elevating Inosine on Early Parkinson Disease Progression, 2021, JAMA
  • Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson Disease, 2020, JAMA Neurology
  • Ferroptosis in Parkinson's disease: Molecular mechanisms and therapeutic potential, 2023, Ageing Research Reviews
  • Differences in the Presentation and Progression of Parkinson's Disease by Sex, 2020, Movement Disorders

David Simon frequently collaborates with other researchers. Notable coauthors include Simona Eleuteri, Michael A. Schwarzschild, Tanya Simuni, Robert A. Hauser, and Brian Fiske.

Best Publications

  • Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators

    Julie St-Pierre;Stavit Drori;Marc Uldry;Jessica M. Silvaggi

  • Initiation of Inappropriate Antimicrobial Therapy Results in a Fivefold Reduction of Survival in Human Septic Shock

    Anand Kumar;Anand Kumar;Paul Ellis;Yaseen Arabi;Dan Roberts

  • Epidemiology of Tension-Type Headache

    Brian S. Schwartz;Walter F. Stewart;David Simon;Richard B. Lipton

  • Parkinson Disease Epidemiology, Pathology, Genetics, and Pathophysiology

    David K. Simon;Caroline M. Tanner;Patrik Brundin

  • Outcomes of Kidney Transplantation in HIV-Infected Recipients

    Peter G. Stock;Burc Barin;Barbara Murphy;Douglas Hanto

  • Locally renewing resident synovial macrophages provide a protective barrier for the joint

    Stephan Culemann;Anika Grüneboom;José Ángel Nicolás-Ávila;Daniela Weidner

  • Medical consultation for migraine: results from the American Migraine Study.

    Richard B. Lipton;Walter F. Stewart;David Simon

  • Urban Environments: Issues on the Peri-Urban Fringe

    David Simon

  • High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer’s disease brain

    Michael T. Lin;David K. Simon;Colette H. Ahn;Lauren M. Kim

  • Development of topographic order in the mammalian retinocollicular projection

    D. K. Simon;D. D. M. O'leary

  • N-methyl-D-aspartate receptor antagonists disrupt the formation of a mammalian neural map.

    David K. Simon;Glen T. Prusky;Dennis D. M. O'Leary;Martha Constantine-Paton

  • Work-Related Disability: Results From the American Migraine Study:

    WF Stewart;RB Lipton;D Simon

  • A Randomized Clinical Trial of High-Dosage Coenzyme Q10 in Early Parkinson Disease: No Evidence of Benefit

    M Flint Beal;David Oakes;Ira Shoulson

  • Meta-analysis of Parkinson's Disease: Identification of a Novel Locus, RIT2

    Nathan Pankratz;Gary W. Beecham;Anita L. Destefano;Ted M. Dawson

  • Non-invasive brain stimulation for Parkinson’s disease: a systematic review and meta-analysis of the literature

    Felipe Fregni;D. K. Simon;A. Wu;A. Pascual-Leone

  • Pioglitazone in early Parkinson's disease: a phase 2, multicentre, double-blind, randomised trial

    Tanya Simuni;Karl Kieburtz;Barbara Tilley;Jordan J Elm

  • A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease

    Karl Kieburtz;Bernard Ravina;Bernard Ravina;Wendy R. Galpern;Barbara Tilley

  • Past adult lead exposure is associated with longitudinal decline in cognitive function

    Brian S. Schwartz;W. F. Stewart;K. I. Bolla;D. Simon

  • Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease

    Tatiana Foroud;S. K. Uniacke;L. Liu;Nathan D Pankratz

  • Outcomes of liver transplant recipients with hepatitis C and human immunodeficiency virus coinfection.

    Norah A. Terrault;Michelle E. Roland;Thomas Schiano;Lorna Dove

Frequent Co-Authors

Georg Schett
Georg Schett University of Erlangen-Nuremberg
Brian S. Schwartz
Brian S. Schwartz Johns Hopkins University
Walter F. Stewart
Walter F. Stewart Sutter Health
Robert A. Hauser
Robert A. Hauser University of South Florida
Hubert H. Fernandez
Hubert H. Fernandez Cleveland Clinic
Klaus Engelke
Klaus Engelke University of Erlangen-Nuremberg
Gerhard Krönke
Gerhard Krönke Charité - University Medicine Berlin
Michael J. Aminoff
Michael J. Aminoff University of California, San Francisco
Alexis Brice
Alexis Brice Institut du Cerveau
Caroline M. Tanner
Caroline M. Tanner University of California, San Francisco

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