World's Best Scientists 2026 revealed!
Christine Klein

Christine Klein

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Best Female Scientists
2025
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Genetics
Germany
2024

D-Index & Metrics

Best Female Scientists

D-Index
110
Citations
48563
World Ranking
883
National Ranking
36

Neuroscience

D-Index
113
Citations
51364
World Ranking
486
National Ranking
34

Genetics

D-Index
108
Citations
43210
World Ranking
565
National Ranking
46

Medicine

D-Index
113
Citations
51610
World Ranking
4916
National Ranking
271

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2024 - Research.com Genetics in Germany Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Germany Leader Award
  • 2023 - Research.com Genetics in Germany Leader Award
  • 2021 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Neurosciences
  • 1968 - Fellow of American Physical Society (APS)

Overview

Christine Klein is affiliated with the University of Lübeck in Germany. Their research primarily focuses on various aspects of Parkinson's disease and related neurological disorders. Their publication record spans multiple high-impact journals and covers a wide spectrum of topics within medicine, biochemistry, genetics, and neuroscience.

Their frequent publication venues include:

  • Movement Disorders
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Parkinsonism & Related Disorders
  • Annals of Neurology
  • npj Parkinson's Disease

Key co-authors who have frequently collaborated with Christine Klein are:

  • Katja Lohmann
  • Norbert Brüggemann
  • Joanne Trinh
  • Max Borsche
  • Ana Westenberger

Their main fields of study include Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. Subfields of focus highlight Neurology, Molecular Biology, Cellular and Molecular Neuroscience, Genetics, and Physiology.

Christine Klein's research covers major topics such as:

  • Parkinson's Disease Mechanisms and Treatments
  • Neurological Disorders and Treatments
  • Genetic Neurodegenerative Diseases
  • Neurological Diseases and Metabolism
  • Lysosomal Storage Disorders Research
  • RNA Regulation and Disease
  • Nuclear Receptors and Signaling

Among their recent published papers are:

  • "Parkinson's disease," 2021, The Lancet
  • "LRRK2 in Parkinson disease: challenges of clinical trials," 2020, Nature Reviews Neurology
  • "A biological classification of Parkinson's disease: the SynNeurGe research diagnostic criteria," 2024, The Lancet Neurology
  • "Mitochondria and Parkinson's Disease: Clinical, Molecular, and Translational Aspects," 2020, Journal of Parkinson's Disease
  • "Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism," 2020, Brain

Best Publications

  • Phenomenology and classification of dystonia: a consensus update.

    Alberto Albanese;Kailash Bhatia;Susan B. Bressman;Mahlon R. DeLong

  • Genome-wide association study reveals genetic risk underlying Parkinson's disease

    Javier Simón-Sánchez;Claudia Schulte;Jose M Bras;Jose M Bras;Manu Sharma

  • Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

    Daniel G Healy;Mario Falchi;Sean S O'Sullivan;Vincenzo Bonifati

  • Genetics of Parkinson’s Disease

    Christine Klein;Ana Westenberger

  • Parkin and PINK1 mitigate STING-induced inflammation

    Danielle A. Sliter;Jennifer Martinez;Ling Hao;Xi Chen

  • Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

    J.A. Obeso;M. Stamelou;M. Stamelou;C.G. Goetz;W. Poewe

  • LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews.

    Laurie J. Ozelius;Geetha Senthil;Rachel Saunders-Pullman;Erin Ohmann

  • Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: the PDGene database.

    Christina M. Lill;Johannes T. Roehr;Johannes T. Roehr;Matthew B. McQueen;Fotini K. Kavvoura;Fotini K. Kavvoura;Fotini K. Kavvoura

  • Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson’s Disease

    Oliver Cooper;Hyemyung Seo;Shaida Andrabi;Cristina Guardia-Laguarta

  • Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells.

    Philip Seibler;John Graziotto;Hyun Jeong;Filip Simunovic

  • A G Protein-coupled Receptor for UDP-glucose

    Jon K. Chambers;Lynn E. Macdonald;Henry M. Sarau;Robert S. Ames

  • The DYT1 phenotype and guidelines for diagnostic testing

    Susan B Bressman;C Sabatti;Deborah Raymond;D de Leon

  • A Major Lung Cancer Susceptibility Locus Maps to Chromosome 6q23–25

    J. E. Bailey-Wilson;C. I. Amos;S. M. Pinney;G. M. Petersen

  • LRRK2 in Parkinson disease: challenges of clinical trials.

    Eduardo Tolosa;Miquel Vila;Miquel Vila;Christine Klein;Olivier Rascol

  • Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration

    Benjamin Dehay;Alfredo Ramirez;Marta Martinez-Vicente;Celine Perier

  • PINK1 Loss of Function Mutations Affect Mitochondrial Complex I Activity via NdufA10 Ubiquinone Uncoupling

    Vanessa A. Morais;Dominik Haddad;Katleen Craessaerts;Pieter-Jan De Bock

  • Lysosomal impairment in Parkinson's disease.

    Benjamin Dehay;Marta Martinez-Vicente;Guy A. Caldwell;Kim A. Caldwell

  • Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study.

    Owen A. Ross;Alexandra I. Soto-Ortolaza;Michael G. Heckman;Jan O. Aasly

  • Deciphering the role of heterozygous mutations in genes associated with parkinsonism.

    Christine Klein;Christine Klein;Katja Lohmann-Hedrich;Ekaterina Rogaeva;Michael G Schlossmacher

  • Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice

    Annika Keller;Annika Keller;Annika Keller;Ana Westenberger;Maria J Sobrido;Maria García-Murias

Frequent Co-Authors

Alexander Münchau
Alexander Münchau University of Lübeck
Laurie J. Ozelius
Laurie J. Ozelius Harvard University
Anthony E. Lang
Anthony E. Lang University of Toronto
Thomas Gasser
Thomas Gasser University of Tübingen
Susan B. Bressman
Susan B. Bressman Mount Sinai Beth Israel
Patricia L. Kramer
Patricia L. Kramer Oregon Health & Science University
Carolyn M. Sue
Carolyn M. Sue Royal North Shore Hospital
Alfredo Ramirez
Alfredo Ramirez University of Cologne
Eberhard Schwinger
Eberhard Schwinger University of Lübeck
Daniela Berg
Daniela Berg University Hospital Schleswig-Holstein

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