World's Best Scientists 2026 revealed!
Alfredo Ramirez

Alfredo Ramirez

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
31308
World Ranking
8042
National Ranking
591

Overview

Alfredo Ramirez is affiliated with the University of Cologne in Germany and has a significant research presence in the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. Their work encompasses numerous subfields, including Physiology, Psychiatry and Mental Health, Molecular Biology, Genetics, and Neurology.

Their main research topics focus extensively on Alzheimer's disease research and treatments, dementia and cognitive impairment research, genetic associations and epidemiology, functional brain connectivity studies, neuroinflammation and neurodegeneration mechanisms, tryptophan and brain disorders, and nutritional studies and diet.

Recent publications by Alfredo Ramirez include:

  • Neuroinflammation in Alzheimer disease, 2024, published in Nature Reviews. Immunology
  • Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease, 2022, published in Nature Genetics
  • Neuroimmune Connections in Aging and Neurodegenerative Diseases, 2020, published in Trends in Immunology
  • Mediterranean Diet, Alzheimer Disease Biomarkers, and Brain Atrophy in Old Age, 2021, published in Neurology
  • Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS, 2024, published in Nature Medicine

Alfredo Ramirez frequently collaborates with several co-authors, including Michael Wagner, Oliver Peters, Anja Schneider, Annika Spottke, and Josef Priller.

The scientist's works have appeared in various publications, with notable numbers in Alzheimer's & Dementia, bioRxiv (Cold Spring Harbor Laboratory), Alzheimer's Research & Therapy, Neurology, and Brain.

Best Publications

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

    Antonio F. Pardiñas;Peter Holmans;Andrew J. Pocklington;Valentina Escott-Price

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase.

    Alfredo Ramirez;André Heimbach;Jan Gründemann;Barbara Stiller

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.

    Gernot Kleinberger;Yoshinori Yamanishi;Marc Suárez-Calvet;Eva Czirr

  • Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

    Gail Davies;Max Lam;Sarah E. Harris;Joey W. Trampush

  • Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D

    Bolz H;von Brederlow B;Ramírez A;Bryda Ec

  • Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies

    Karsten Haug;Maike Warnstedt;Alexi K Alekov;Thomas Sander

  • G protein-coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth.

    Sandra M Pasternack;Ivar von Kügelgen;Khalid Al Aboud;Young-Ae Lee;Young-Ae Lee

  • One at a time, live tracking of NGF axonal transport using quantum dots.

    Bianxiao Cui;Chengbiao Wu;Liang Chen;Alfredo Ramirez

  • Common polygenic variation enhances risk prediction for Alzheimer's disease.

    Valentina Escott-Price;Rebecca Sims;Christian Bannister;Denise Harold

  • Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration

    Benjamin Dehay;Alfredo Ramirez;Marta Martinez-Vicente;Celine Perier

  • Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

    Piotr Lewczuk;Peter Riederer;Sid E. O’Bryant;Marcel M. Verbeek

  • A Pan‐European Study of the C9orf72 Repeat Associated with FTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats

    Julie van der Zee;Ilse Gijselinck;Lubina Dillen;Tim Van Langenhove

  • A novel Alzheimer disease locus located near the gene encoding tau protein

    G. Jun;C. A. Ibrahim-Verbaas;M. Vronskaya;J-C Lambert;J-C Lambert;J-C Lambert

  • Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

    Itziar de Rojas;Itziar de Rojas;Sonia Moreno-Grau;Sonia Moreno-Grau;Niccolo Tesi;Benjamin Grenier-Boley

  • Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE).

    Frank Jessen;Frank Jessen;Annika Spottke;Annika Spottke;Henning Boecker;Henning Boecker;Frederic Brosseron

  • Associations of paediatric demyelinating and encephalitic syndromes with myelin oligodendrocyte glycoprotein antibodies: a multicentre observational study.

    Thaís Armangue;Gemma Olivé-Cirera;Eugenia Martínez-Hernandez;Maria Sepulveda

  • Mutations in CAV3 cause mechanical hyperirritability of skeletal muscle in rippling muscle disease

    Regina C. Betz;Benedikt G. H. Schoser;Dagmar Kasper;Kenneth Ricker

Frequent Co-Authors

Frank Jessen
Frank Jessen University of Cologne
Michael Wagner
Michael Wagner TU Dresden
Jens Wiltfang
Jens Wiltfang University of Göttingen
Oliver Peters
Oliver Peters German Center for Neurodegenerative Diseases
Michael T. Heneka
Michael T. Heneka University Hospital Bonn
Wolfgang Maier
Wolfgang Maier University of Bonn
Céline Bellenguez
Céline Bellenguez Institut Pasteur
Emrah Düzel
Emrah Düzel German Center for Neurodegenerative Diseases
Tim Becker
Tim Becker University of Bonn

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