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Lindsay A. Farrer

Lindsay A. Farrer

D-Index & Metrics

Genetics

D-Index
128
Citations
78558
World Ranking
272
National Ranking
143

Medicine

D-Index
132
Citations
87925
World Ranking
2276
National Ranking
1285

Research.com Recognitions

  • 1991 - Fellow of Alfred P. Sloan Foundation

Overview

Lindsay A. Farrer is affiliated with Boston University in the United States and specializes in research within biochemistry, genetics, molecular biology, and medicine. Their work spans numerous subfields including molecular biology, genetics, physiology, psychiatry and mental health, and neurology.

The main research topics covered by Farrer's publications include genetic associations and epidemiology, Alzheimer's disease research and treatments, bioinformatics and genomic networks, dementia and cognitive impairment research, epigenetics and DNA methylation, genomics and rare diseases, and genetics and neurodevelopmental disorders.

Frequent coauthors collaborating with Farrer are:

  • Jesse Mez
  • Jonathan L. Haines
  • Richard Mayeux
  • Margaret A. Pericak-Vance
  • Eden R. Martin

Similarly, the prominent venues where Farrer's research has been published include:

  • Alzheimer s & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Translational Psychiatry
  • Alzheimer s Research & Therapy
  • Nature Genetics

Notable recent papers authored or coauthored by Farrer include:

  • Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study (2020, Nature Communications)
  • A large-scale genome-wide association study meta-analysis of cannabis use disorder (2020, The Lancet Psychiatry)
  • Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel (2020, JAMA Neurology)
  • APOE Genotype and Alzheimer Disease Risk Across Age, Sex, and Population Ancestry (2023, JAMA Neurology)
  • Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders (2023, Nature Mental Health)

Farrer's academic contributions have been recognized with the award of Fellow of the Alfred P. Sloan Foundation in 1991.

Best Publications

  • Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease: A Meta-analysis

    Lindsay A. Farrer;L. Adrienne Cupples;Jonathan L. Haines;Bradley T Hyman

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Complement Factor H Polymorphism and Age-Related Macular Degeneration

    Albert O. Edwards;Robert Ritter;Kenneth J. Abel;Alisa Manning

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Genome-wide analysis of genetic loci associated with Alzheimer disease.

    Sudha Seshadri;Annette L. Fitzpatrick;M Arfan Ikram;Anita L. DeStefano

  • A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

    Lars G. Fritsche;Wilmar Igl;Jessica N.Cooke Bailey;Felix Grassmann

  • The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

    Ekaterina Rogaeva;Ekaterina Rogaeva;Yan Meng;Joseph H. Lee;Yongjun Gu;Yongjun Gu

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing

    Gang Yu;Masaki Nishimura;Shigeki Arawaka;Shigeki Arawaka;Diane Levitan

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions

    Seema Qamar;Guo Zhen Wang;Suzanne J. Randle;Francesco Simone Ruggeri

  • Seven new loci associated with age-related macular degeneration

    Lars G. Fritsche;Lars G. Fritsche;Wei Chen;Wei Chen;Matthew Schu;Brian L. Yaspan

  • Depression as a risk factor for Alzheimer disease: the MIRAGE Study.

    Robert C. Green;L. Adrienne Cupples;Alex Kurz;Sanford Auerbach

  • Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

    Raymond K. Walters;Raymond K. Walters;Renato Polimanti;Emma C. Johnson;Jeanette N. McClintick

  • The PhenX Toolkit: Get the Most From Your Measures

    Carol M. Hamilton;Lisa C. Strader;Joseph G. Pratt;Deborah Maiese

  • Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14

    P. St George-Hyslop;J. Haines;E. Rogaev;E. Rogaev;M. Mortilla;M. Mortilla

  • Head injury and the risk of AD in the MIRAGE study

    Z. Guo;L. A. Cupples;A. Kurz;S. H. Auerbach

  • Genetic variants near TIMP3 and high-density lipoprotein–associated loci influence susceptibility to age-related macular degeneration

    Wei Chen;Dwight Stambolian;Albert O. Edwards;Kari E. Branham

  • Lack of association between angiotensin-converting enzyme and dementia of the Alzheimer’s type in an elderly Arab population in Wadi Ara, Israel

    Abdalla Bowirrat;Jing Cui;Kristin Waraska;Robert P Friedland

Frequent Co-Authors

Margaret A. Pericak-Vance
Margaret A. Pericak-Vance University of Miami
Joel Gelernter
Joel Gelernter Yale University
Henry R. Kranzler
Henry R. Kranzler University of Pennsylvania
Richard Mayeux
Richard Mayeux Columbia University
Gerard D. Schellenberg
Gerard D. Schellenberg University of Pennsylvania
Jonathan L. Haines
Jonathan L. Haines Case Western Reserve University
Clinton T. Baldwin
Clinton T. Baldwin Boston University
Kathryn L. Lunetta
Kathryn L. Lunetta Boston University
Peter St George-Hyslop
Peter St George-Hyslop Columbia University
Adam C. Naj
Adam C. Naj University of Pennsylvania

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