World's Best Scientists 2026 revealed!
Kathryn L. Lunetta

Kathryn L. Lunetta

D-Index & Metrics

Genetics

D-Index
105
Citations
58034
World Ranking
619
National Ranking
312

Medicine

D-Index
106
Citations
59205
World Ranking
6385
National Ranking
3403

Overview

Kathryn L. Lunetta is affiliated with Boston University in the United States. Their research spans multiple disciplines within biochemistry, genetics, molecular biology, and medicine, with a focus on genetics, molecular biology, physiology, cardiology and cardiovascular medicine, and neurology.

The scientist has contributed extensively to studies on genetic associations and epidemiology, as well as research related to Alzheimer's disease, BRCA gene mutations in cancer, bioinformatics and genomic networks, epigenetics and DNA methylation, neuroinflammation and neurodegeneration mechanisms, and dementia and cognitive impairment.

Notable recent publications include:

  • Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study, 2020, Nature Communications
  • Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging, 2021, Genome Biology
  • Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women, 2021, Nature Communications
  • Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank, 2022, Nature Genetics
  • Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry, 2021, JNCI Journal of the National Cancer Institute

Their frequent co-authors include Lindsay A. Farrer, Joanne M. Murabito, Jesse Mez, Julie R. Palmer, and Christine B. Ambrosone.

Publication venues where this researcher commonly publishes are:

  • UNC Libraries
  • Alzheimer s & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Innovation in Aging
  • Nature Communications

Main fields of study represented in their work are:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields within these broader fields addressed by their research include:

  • Genetics
  • Molecular Biology
  • Physiology
  • Cardiology and Cardiovascular Medicine
  • Neurology

Core topics of their work encompass:

  • Genetic Associations and Epidemiology
  • Alzheimer's disease research and treatments
  • BRCA gene mutations in cancer
  • Bioinformatics and Genomic Networks
  • Epigenetics and DNA Methylation
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Dementia and Cognitive Impairment Research

Best Publications

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

  • Common variants at 30 loci contribute to polygenic dyslipidemia.

    Sekar Kathiresan;Sekar Kathiresan;Sekar Kathiresan;Cristen J. Willer;Gina M. Peloso;Serkalem Demissie

  • The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

    Ekaterina Rogaeva;Ekaterina Rogaeva;Yan Meng;Joseph H. Lee;Yongjun Gu;Yongjun Gu

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • DNA methylation age of blood predicts all-cause mortality in later life.

    Riccardo E Marioni;Riccardo E Marioni;Sonia Shah;Allan F McRae;Brian H Chen

  • DNA methylation-based measures of biological age: meta-analysis predicting time to death

    Brian H. Chen;Riccardo E. Marioni;Riccardo E. Marioni;Elena Colicino;Marjolein J. Peters

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts.

    Bruce M. Psaty;Christopher J. O'Donnell;Vilmundur Gudnason;Kathryn L. Lunetta

  • Mutation Spectrum and Genotype-Phenotype Analyses in Cowden Disease and Bannayan-Zonana Syndrome, Two Hamartoma Syndromes With Germline PTEN Mutation

    Debbie J. Marsh;Valérie Coulon;Kathryn L. Lunetta;Philippe Rocca-Serra

  • Multi-Ethnic Genome-wide Association Study for Atrial Fibrillation

    Carolina Roselli;Mark D. Chaffin;Lu Chen Weng;Lu Chen Weng;Stefanie Aeschbacher

  • Meta-analysis identifies six new susceptibility loci for atrial fibrillation

    Patrick T Ellinor;Kathryn L Lunetta;Christine M Albert;Christine M Albert;Nicole L Glazer

  • Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

    John R.B. Perry;Felix Day;Cathy E. Elks;Patrick Sulem

  • PTEN Mutation Spectrum and Genotype-Phenotype Correlations in Bannayan-Riley-Ruvalcaba Syndrome Suggest a Single Entity With Cowden Syndrome

    Debbie J. Marsh;Debbie J. Marsh;Jennifer B. Kum;Jennifer B. Kum;Kathryn L. Lunetta;Michael J. Bennett

  • Screening large-scale association study data: exploiting interactions using random forests

    Kathryn L Lunetta;L Brooke Hayward;Jonathan Segal;Paul Van Eerdewegh

  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

    Felix R. Day;Deborah J. Thompson;Hannes Helgason;Hannes Helgason;Daniel I. Chasman

  • Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

    Cathy E. Elks;John R B Perry;Patrick Sulem;Daniel I. Chasman

  • Common variants in KCNN3 are associated with lone atrial fibrillation

    Patrick T. Ellinor;Kathryn L. Lunetta;Kathryn L. Lunetta;Nicole L. Glazer;Arne Pfeufer

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

Frequent Co-Authors

Lindsay A. Farrer
Lindsay A. Farrer Boston University
Joanne M. Murabito
Joanne M. Murabito Boston University
Emelia J. Benjamin
Emelia J. Benjamin Boston University
Patrick T. Ellinor
Patrick T. Ellinor Harvard University
Bruce M. Psaty
Bruce M. Psaty University of Washington
Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston
Margaret A. Pericak-Vance
Margaret A. Pericak-Vance University of Miami
Steven A. Lubitz
Steven A. Lubitz Harvard University
Philip L. De Jager
Philip L. De Jager Columbia University
Richard Mayeux
Richard Mayeux Columbia University

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