World's Best Scientists 2026 revealed!
L. Adrienne Cupples

L. Adrienne Cupples

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Best Scientists
2025
Award Badge
Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
193
Citations
164507
World Ranking
23
National Ranking
17

Best Scientists

D-Index
193
Citations
164507
World Ranking
373
National Ranking
247

Medicine

D-Index
195
Citations
169110
World Ranking
213
National Ranking
142

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2025 - Research.com Best Scientists Award

Overview

L. Adrienne Cupples was affiliated with Boston University in the United States. Their research spanned multiple key areas within biochemistry, genetics, and molecular biology, with significant contributions also in medicine.

The main fields of study associated with their work included:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their research delved into several subfields such as:

  • Genetics
  • Molecular Biology
  • Physiology
  • Surgery
  • Statistics and Probability

Cupples' scientific output covered a variety of important topics, including:

  • Genetic Associations and Epidemiology
  • Epigenetics and DNA Methylation
  • Genomics and Rare Diseases
  • Bioinformatics and Genomic Networks
  • RNA modifications and cancer
  • Lipoproteins and Cardiovascular Health
  • Nutrition, Genetics, and Disease

Their research was published extensively in high-profile and specialized venues. Frequent publication venues included:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Circulation
  • Nature Genetics

Some of their recent papers are as follows:

  • Inherited causes of clonal haematopoiesis in 97,691 whole genomes, 2020, Nature
  • Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale, 2020, Nature Genetics
  • Association of clonal hematopoiesis with chronic obstructive pulmonary disease, 2021, Blood
  • Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention, 2022, Nature Genetics
  • Small Dense Low-Density Lipoprotein Cholesterol Is the Most Atherogenic Lipoprotein Parameter in the Prospective Framingham Offspring Study, 2021, Journal of the American Heart Association

Cupples frequently collaborated with several researchers over the course of their career. Notable coauthors included:

  • Ramachandran S. Vasan
  • Bruce M. Psaty
  • Eric Boerwinkle
  • Jerome I. Rotter
  • Joshua C. Bis

Best Publications

  • Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease: A Meta-analysis

    Lindsay A. Farrer;L. Adrienne Cupples;Jonathan L. Haines;Bradley T Hyman

  • Biological, clinical and population relevance of 95 loci for blood lipids

    Tanya M. Teslovich;Kiran Musunuru;Albert V. Smith;Andrew C. Edmondson

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    Elizabeth K. Speliotes;Elizabeth K. Speliotes;Cristen J. Willer;Sonja I. Berndt;Keri L. Monda

  • Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study.

    Caroline S. Fox;Joseph M. Massaro;Udo Hoffmann;Karla M. Pou

  • Discovery and refinement of loci associated with lipid levels

    Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta;Gina M. Peloso;Gina M. Peloso;Gina M. Peloso

  • Plasma HDL cholesterol and risk of myocardial infarction: A mendelian randomisation study

    Benjamin F. Voight;Benjamin F. Voight;Benjamin F. Voight;Gina M. Peloso;Gina M. Peloso;Marju Orho-Melander;Ruth Frikke-Schmidt

  • A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

    M Nikpay;A Goel;Won H-H.;L M Hall

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    Hana Lango Allen;Karol Estrada;Guillaume Lettre;Sonja I. Berndt

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

  • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

    Heribert Schunkert;Inke R. König;Sekar Kathiresan;Muredach P. Reilly

  • Genetic studies of body mass index yield new insights for obesity biology

    Adam E. Locke;Bratati Kahali;Sonja I. Berndt;Anne E. Justice

  • Common variants at 30 loci contribute to polygenic dyslipidemia.

    Sekar Kathiresan;Sekar Kathiresan;Sekar Kathiresan;Cristen J. Willer;Gina M. Peloso;Serkalem Demissie

  • The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

    Ekaterina Rogaeva;Ekaterina Rogaeva;Yan Meng;Joseph H. Lee;Yongjun Gu;Yongjun Gu

  • Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

    Karol Estrada;Unnur Styrkarsdottir;Evangelos Evangelou;Yi-Hsiang Hsu

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    E. K. Speliotes;C. J. Willer;S. I. Berndt;K. L. Monda

  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

    Mary F. Feitosa;Aldi T. Kraja;Daniel I. Chasman;Yun J. Sung

  • A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

    Majid Nikpay;Anuj Goel;Hong-Hee Won;Leanne M. Hall

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    H. Lango Allen;K. Estrada;G. Lettre;S. I. Berndt

Frequent Co-Authors

Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston
Bruce M. Psaty
Bruce M. Psaty University of Washington
Caroline S. Fox
Caroline S. Fox MSD (United States)
Christopher J. O'Donnell
Christopher J. O'Donnell Harvard Medical School
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Jerome I. Rotter
Jerome I. Rotter UCLA Medical Center
Albert Hofman
Albert Hofman Harvard University
Douglas P. Kiel
Douglas P. Kiel Beth Israel Deaconess Medical Center
Sekar Kathiresan
Sekar Kathiresan Harvard University
Albert V. Smith
Albert V. Smith University of Michigan–Ann Arbor

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