What is she best known for?
The fields of study she is best known for:
Margaret A. Pericak-Vance spends much of her time researching Genetics, Allele, Genome-wide association study, Locus and Genetic linkage.
Her Genetics study frequently links to related topics such as Autism.
Her Allele research includes themes of Multiple sclerosis, Immunology, Apolipoprotein E and Genotype.
Her Genome-wide association study study also includes
- Alzheimer's disease which is related to area like Degenerative disease, Dementia and Age of onset,
- Case-control study and related Macular degeneration.
Her research in Locus tackles topics such as Chromosome which are related to areas like Linkage.
Her Genetic linkage research includes elements of Chromosome 21, Amyotrophic lateral sclerosis, Genome, Genetic marker and Candidate gene.
Her most cited work include:
- Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families (7318 citations)
- Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. (4020 citations)
- Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. (3630 citations)
What are the main themes of her work throughout her whole career to date?
Her main research concerns Genetics, Disease, Genetic linkage, Gene and Allele.
Her Locus, Genome-wide association study, Single-nucleotide polymorphism, Genetic association and Haplotype investigations are all subjects of Genetics research.
Margaret A. Pericak-Vance has researched Disease in several fields, including Oncology and Bioinformatics.
Her Genetic linkage research is multidisciplinary, incorporating elements of Genetic marker, Chromosome, Gene mapping, Genetic heterogeneity and Linkage.
She works mostly in the field of Allele, limiting it down to topics relating to Apolipoprotein E and, in certain cases, Alzheimer's disease.
Her Alzheimer's disease study integrates concerns from other disciplines, such as Age of onset and Degenerative disease.
She most often published in these fields:
- Genetics (65.83%)
- Disease (21.48%)
- Genetic linkage (18.00%)
What were the highlights of her more recent work (between 2015-2021)?
- Genetics (65.83%)
- Disease (21.48%)
- Genome-wide association study (16.09%)
In recent papers she was focusing on the following fields of study:
Genetics, Disease, Genome-wide association study, Alzheimer's disease and Gene are her primary areas of study.
Her study in Genetics focuses on Locus, Allele, Exome sequencing, Genetic association and Single-nucleotide polymorphism.
Her Locus study frequently intersects with other fields, such as Genetic linkage.
Her work in Allele covers topics such as Apolipoprotein E which are related to areas like Oncology and Demography.
Her study looks at the relationship between Disease and fields such as Gerontology, as well as how they intersect with chemical problems.
The Genome-wide association study study combines topics in areas such as Genomics, Glaucoma, Open angle glaucoma, Minor allele frequency and Haplotype.
Between 2015 and 2021, her most popular works were:
- A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants (720 citations)
- Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism (538 citations)
- Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease (496 citations)
In her most recent research, the most cited papers focused on:
- Gene
- Mutation
- Internal medicine
Her primary scientific interests are in Genetics, Genome-wide association study, Gene, Allele and Disease.
Her research is interdisciplinary, bridging the disciplines of Alzheimer's disease and Genetics.
Her studies in Genome-wide association study integrate themes in fields like Linkage disequilibrium, Allele frequency, Genomics and Glaucoma, Open angle glaucoma.
Her Gene research integrates issues from Multiple sclerosis and Cancer research.
Her studies deal with areas such as Odds ratio, Apolipoprotein E and Immunology as well as Allele.
Within one scientific family, Margaret A. Pericak-Vance focuses on topics pertaining to Genetic variation under Disease, and may sometimes address concerns connected to Candidate gene.
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