World's Best Scientists 2026 revealed!
Margaret A. Pericak-Vance

Margaret A. Pericak-Vance

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Best Scientists
2025
Award Badge
Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
179
Citations
191227
World Ranking
47
National Ranking
31

Best Scientists

D-Index
179
Citations
191227
World Ranking
621
National Ranking
388

Genetics

D-Index
178
Citations
190595
World Ranking
47
National Ranking
29

Medicine

D-Index
180
Citations
199248
World Ranking
361
National Ranking
227

Research.com Recognitions

  • 2026 - Research.com Genetics in United States Leader Award
  • 2025 - Research.com Best Female Scientists Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Genetics in United States Leader Award
  • 2024 - Research.com Genetics in United States Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United States Leader Award
  • 2023 - Research.com Genetics in United States Leader Award
  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2003 - Member of the National Academy of Medicine (NAM)
  • 2001 - Grand Prix scientifique de la Fondation Louis D., Institut de France

Overview

Margaret A. Pericak-Vance is affiliated with the University of Miami in the United States. Their research spans multiple fields, primarily within biochemistry, genetics, and molecular biology, as well as medicine. The subfields they focus on include molecular biology, genetics, physiology, psychiatry and mental health, and neurology.

The key topics in their work include genetic associations and epidemiology, Alzheimer's disease research and treatments, bioinformatics and genomic networks, dementia and cognitive impairment research, epigenetics and DNA methylation, genomics and rare diseases, and mitochondrial function and pathology.

The scientist has contributed to research published mainly in venues such as Alzheimer's & Dementia, bioRxiv (Cold Spring Harbor Laboratory), International Psychogeriatrics, Alzheimer's Research & Therapy, and Human Molecular Genetics. The distribution of their publications highlights 7 papers in Alzheimer's & Dementia, indicating a significant focus in that journal.

Recent papers by Margaret A. Pericak-Vance include:

  • "Blood-derived mitochondrial DNA copy number is associated with Alzheimer disease, Alzheimer-related biomarkers and serum metabolites" (2024, Alzheimer's Research & Therapy)
  • "Genetic analysis of cognitive preservation in the midwestern Amish reveals a novel locus on chromosome 2" (2024, Alzheimer's & Dementia)
  • "Novel early-onset Alzheimer-associated genes influence risk through dysregulation of glutamate, immune activation, and intracellular signaling pathways" (2025, Alzheimer's & Dementia)
  • "Developing biobanking processes for Alzheimer's disease and related dementia research in Africa: Experience from the Recruitment and Retention for Alzheimer's Disease Diversity in the Alzheimer's Disease Sequencing Project (READD-ADSP)" (2025, Alzheimer's & Dementia)
  • "APOE and Alzheimer's disease and related dementias risk among 12,221 Hispanics/Latinos" (2025, Alzheimer's & Dementia)

Coauthors frequently collaborating with this researcher include Michael L. Cuccaro, Jeffery M. Vance, Anthony J. Griswold, Brian W. Kunkle, and Jonathan L. Haines. These collaborations have contributed to advancing research in their field.

The scientist has received several awards: they were elected a Member of the National Academy of Medicine in 2003, named a Fellow of the American Association for the Advancement of Science (AAAS) in 2011, and were a recipient of the Grand Prix scientifique de la Fondation Louis D., Institut de France in 2001.

Best Publications

  • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

    E. H. Corder;A. M. Saunders;W. J. Strittmatter;D. E. Schmechel

  • Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease.

    Alison Goate;Marie-Christine Chartier-Harlin;Mike Mullan;Jeremy Brown

  • Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease: A Meta-analysis

    Lindsay A. Farrer;L. Adrienne Cupples;Jonathan L. Haines;Bradley T Hyman

  • Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

    Warren J. Strittmatter;Ann M. Saunders;Donald Schmechel;Margaret Pericak-Vance

  • Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

    R. Sherrington;E. I. Rogaev;Y. Liang;E. A. Rogaeva

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease.

    A. M. Saunders;W. J. Strittmatter;D. Schmechel;P. H. St. George-Hyslop

  • Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.

    T. J. Kwiatkowski;D. A. Bosco;D. A. Bosco;A. L. LeClerc;A. L. LeClerc;E. Tamrazian

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • Complement factor H variant increases the risk of age-related macular degeneration.

    Jonathan L. Haines;Michael A. Hauser;Silke Schmidt;William K. Scott

  • Risk alleles for multiple sclerosis identified by a genomewide study.

    David A. Hafler;Alastair Compston;Stephen Sawcer;Mark J. Daly

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Functional impact of global rare copy number variation in autism spectrum disorders

    Dalila Pinto;Alistair T. Pagnamenta;Lambertus Klei;Richard Anney

  • Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease.

    Corder Eh;Saunders Am;Risch Nj;Strittmatter Wj

  • Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism

    F. Kyle Satterstrom;F. Kyle Satterstrom;Jack A. Kosmicki;Jiebiao Wang;Michael S. Breen

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A.

    Stephan Züchner;Stephan Züchner;Irina V Mersiyanova;Maria Muglia;Nisrine Bissar-Tadmouri;Nisrine Bissar-Tadmouri

  • Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

    Han Xiang Deng;Afif Hentati;John A. Tainer;Zafar Iqbal

  • Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

    D E Schmechel;A M Saunders;W J Strittmatter;B J Crain

  • Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

    Warren J. Strittmatter;Karl H. Weisgraber;David Y. Huang;Li Ming Dong

Frequent Co-Authors

Jonathan L. Haines
Jonathan L. Haines Case Western Reserve University
Jeffery M. Vance
Jeffery M. Vance University of Miami
William K. Scott
William K. Scott University of Miami
Eden R. Martin
Eden R. Martin University of Miami
John R. Gilbert
John R. Gilbert University of Miami
Gary W. Beecham
Gary W. Beecham University of Miami
Lindsay A. Farrer
Lindsay A. Farrer Boston University
Gerard D. Schellenberg
Gerard D. Schellenberg University of Pennsylvania
Michael L. Cuccaro
Michael L. Cuccaro University of Miami
Richard Mayeux
Richard Mayeux Columbia University

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