World's Best Scientists 2026 revealed!
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Genetics
USA
2026

D-Index & Metrics

Genetics

D-Index
161
Citations
136843
World Ranking
94
National Ranking
46

Medicine

D-Index
161
Citations
137362
World Ranking
733
National Ranking
416

Research.com Recognitions

  • 2026 - Research.com Genetics in United States Leader Award
  • 2025 - Research.com Genetics in United States Leader Award
  • 2024 - Research.com Genetics in United States Leader Award
  • 2023 - Research.com Genetics in United States Leader Award
  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jonathan L. Haines is affiliated with Case Western Reserve University in the United States. Their research primarily spans biochemistry, genetics, molecular biology, and medicine with a substantial focus on genetics, molecular biology, physiology, ophthalmology, and psychiatry and mental health.

The scientist's work engages deeply with multiple key topics, including:

  • Genetic Associations and Epidemiology
  • Alzheimer's disease research and treatments
  • Bioinformatics and Genomic Networks
  • Retinal Diseases and Treatments
  • Epigenetics and DNA Methylation
  • Glaucoma and retinal disorders
  • Genomics and Rare Diseases

Notable recent publications include:

  • Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study, 2020, Nature Communications
  • Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries, 2021, Nature Communications
  • Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression, 2020, Nature Genetics
  • Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel, 2020, JAMA Neurology
  • Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease, 2022, Nature Genetics

Frequent co-authors collaborating with Jonathan L. Haines include:

  • Margaret A. Pericak-Vance
  • Michael L. Cuccaro
  • Lindsay A. Farrer
  • Jeffery M. Vance
  • William S. Bush

Publication venues where the scientist has frequently contributed encompass:

  • Alzheimer s & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Annals of Neurology
  • Investigative Ophthalmology & Visual Science

Jonathan L. Haines earned the title of Fellow of the American Association for the Advancement of Science (AAAS) in 2009.

Best Publications

  • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

    E. H. Corder;A. M. Saunders;W. J. Strittmatter;D. E. Schmechel

  • Finding the missing heritability of complex diseases

    Teri A. Manolio;Francis S. Collins;Nancy J. Cox;David B. Goldstein

  • Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease: A Meta-analysis

    Lindsay A. Farrer;L. Adrienne Cupples;Jonathan L. Haines;Bradley T Hyman

  • Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

    R. Sherrington;E. I. Rogaev;Y. Liang;E. A. Rogaeva

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.

    T. J. Kwiatkowski;D. A. Bosco;D. A. Bosco;A. L. LeClerc;A. L. LeClerc;E. Tamrazian

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • Complement factor H variant increases the risk of age-related macular degeneration.

    Jonathan L. Haines;Michael A. Hauser;Silke Schmidt;William K. Scott

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Functional impact of global rare copy number variation in autism spectrum disorders

    Dalila Pinto;Alistair T. Pagnamenta;Lambertus Klei;Richard Anney

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor

    James A. Trofatter;Mia M. MacCollin;Joni L. Rutter;Jill R. Murrell

  • Mapping autism risk loci using genetic linkage and chromosomal rearrangements

    Peter Szatmari;Andrew D. Paterson;Lonnie Zwaigenbaum;Wendy Roberts

  • A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

    Lars G. Fritsche;Wilmar Igl;Jessica N.Cooke Bailey;Felix Grassmann

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

    Ashley H. Beecham;Nikolaos A. Patsopoulos;Nikolaos A. Patsopoulos;Dionysia K. Xifara;Mary F. Davis

  • Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia

    Han-Xiang Deng;Wenjie Chen;Seong‐Tshool Hong;Seong‐Tshool Hong;Kym M Boycott

  • Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

    Joshua C. Denny;Lisa Bastarache;Marylyn D. Ritchie;Robert J. Carroll

  • Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders

    Dalila Pinto;Elsa Delaby;Elsa Delaby;Elsa Delaby;Daniele Merico;Mafalda Barbosa

  • Common genetic variants on 5p14.1 associate with autism spectrum disorders

    Kai Wang;Haitao Zhang;Deqiong Ma;Maja Bucan

Frequent Co-Authors

Margaret A. Pericak-Vance
Margaret A. Pericak-Vance University of Miami
Eden R. Martin
Eden R. Martin University of Miami
Gerard D. Schellenberg
Gerard D. Schellenberg University of Pennsylvania
Lindsay A. Farrer
Lindsay A. Farrer Boston University
William K. Scott
William K. Scott University of Miami
Richard Mayeux
Richard Mayeux Columbia University
Janey L. Wiggs
Janey L. Wiggs Massachusetts Eye and Ear Infirmary
Gary W. Beecham
Gary W. Beecham University of Miami
John R. Gilbert
John R. Gilbert University of Miami
Louis R. Pasquale
Louis R. Pasquale Icahn School of Medicine at Mount Sinai

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