World's Best Scientists 2026 revealed!

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Genetics

D-Index
52
Citations
24908
World Ranking
3751
National Ranking
1617

Biology and Biochemistry

D-Index
53
Citations
25140
World Ranking
15887
National Ranking
6598

Overview

Gary W. Beecham is affiliated with the University of Miami in the United States. Their research centers primarily on genetics and molecular biology within the fields of biochemistry and medicine.

The main topics of their work include:

  • Alzheimer's disease research and treatments
  • Genetic Associations and Epidemiology
  • Dementia and Cognitive Impairment Research
  • Bioinformatics and Genomic Networks
  • Genomics and Rare Diseases
  • Epigenetics and DNA Methylation
  • MicroRNA in disease regulation

Gary W. Beecham's publications demonstrate significant involvement in the study of Alzheimer's disease and associated genetic factors. Notable papers include:

  • "Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study," 2020, Nature Communications
  • "Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease," 2022, Nature Genetics
  • "Early-Onset Alzheimer's Disease: What Is Missing in Research?", 2021, Current Neurology and Neuroscience Reports
  • "Late-onset vs nonmendelian early-onset Alzheimer disease," 2020, Neurology Genetics
  • "Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds," 2021, Alzheimer s & Dementia

The frequent co-authors that appear alongside Beecham are:

  • Michael L. Cuccaro
  • Jeffery M. Vance
  • Margaret A. Pericak-Vance
  • Larry D. Adams
  • Kara L. Hamilton-Nelson

In terms of publication venues, Beecham has contributed to multiple journals including:

  • Alzheimer s & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurology
  • Neurobiology of Aging
  • Journal of Alzheimer s Disease

Their subfields of study consist of genetics, molecular biology, physiology, psychiatry and mental health, and neurology, indicating an interdisciplinary approach to neurological and genetic research.

Best Publications

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: the PDGene database.

    Christina M. Lill;Johannes T. Roehr;Johannes T. Roehr;Matthew B. McQueen;Fotini K. Kavvoura;Fotini K. Kavvoura;Fotini K. Kavvoura

  • Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.

    Todd L. Edwards;Todd L. Edwards;William K. Scott;Cherylyn Almonte;Amber Burt

  • Meta-analysis confirms CR1, CLU, and PICALM as Alzheimer disease risk loci and reveals interactions with APOE genotypes.

    Gyungah Jun;Adam C. Naj;Gary W. Beecham;Li San Wang

  • Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

    Eric M Reiman;Joseph F Arboleda-Velasquez;Yakeel T Quiroz;Matthew J Huentelman

  • Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

    David C. Whitcomb;Jessica LaRusch;Alyssa M. Krasinskas;Lambertus Klei

  • Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior

    Andrea Ganna;Karin J. H. Verweij;Michel G. Nivard;Robert Maier;Robert Maier

  • Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.

    Gary W. Beecham;Kara Hamilton;Adam C. Naj;Eden R. Martin

  • Meta-analysis of Parkinson's Disease: Identification of a Novel Locus, RIT2

    Nathan Pankratz;Gary W. Beecham;Anita L. Destefano;Ted M. Dawson

  • Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.

    Timothy J Hohman;Logan Dumitrescu;Lisa L Barnes;Madhav Thambisetty

  • A novel Alzheimer disease locus located near the gene encoding tau protein

    G. Jun;C. A. Ibrahim-Verbaas;M. Vronskaya;J-C Lambert;J-C Lambert;J-C Lambert

  • Genome-wide Association Study Implicates a Chromosome 12 Risk Locus for Late-Onset Alzheimer Disease

    Gary W. Beecham;Eden R. Martin;Yi Ju Li;Michael A. Slifer

  • A Genome-wide Association Study of Autism Reveals a Common Novel Risk Locus at 5p14.1

    Deqiong Ma;Daria Salyakina;James M. Jaworski;Ioanna Konidari

  • Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

    Joshua C Bis;Xueqiu Jian;Brian W Kunkle;Yuning Chen

  • Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

    Giovanni Coppola;Subashchandrabose Chinnathambi;Jason Ji Yong Lee;Beth A. Dombroski

  • Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.

    Adam C. Naj;Gyungah Jun;Christiane Reitz;Brian W. Kunkle

  • Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

    Joshua C. Bis;Xueqiu Jian;Brian W. Kunkle;Yuning Chen

Frequent Co-Authors

Margaret A. Pericak-Vance
Margaret A. Pericak-Vance University of Miami
Eden R. Martin
Eden R. Martin University of Miami
Jonathan L. Haines
Jonathan L. Haines Case Western Reserve University
Jeffery M. Vance
Jeffery M. Vance University of Miami
Gerard D. Schellenberg
Gerard D. Schellenberg University of Pennsylvania
Richard Mayeux
Richard Mayeux Columbia University
Adam C. Naj
Adam C. Naj University of Pennsylvania
Lindsay A. Farrer
Lindsay A. Farrer Boston University
Michael L. Cuccaro
Michael L. Cuccaro University of Miami
Badri N. Vardarajan
Badri N. Vardarajan Columbia University

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