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Tianlei Ying

Tianlei Ying

D-Index & Metrics

Biology and Biochemistry

D-Index
45
Citations
8352
World Ranking
19098
National Ranking
497

Overview

Tianlei Ying is affiliated with Fudan University in China and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work primarily spans infectious diseases, molecular biology, radiology, nuclear medicine and imaging, immunology, and oncology.

The scientist has focused on areas such as monoclonal and polyclonal antibodies research, SARS-CoV-2 and COVID-19 research, CAR-T cell therapy, clinical studies related to COVID-19, vaccines and immunoinformatics approaches, virus-based gene therapy, and studies of animal virus infections.

Frequent coauthors of Tianlei Ying include Yanling Wu, Shibo Jiang, Zhenlin Yang, Yu Kong, and Xiaolong Tian.

Their publications have appeared in several recurring venues, including bioRxiv (Cold Spring Harbor Laboratory), Signal Transduction and Targeted Therapy, Cellular and Molecular Immunology, Nano Letters, and Cell Discovery.

Among their recent papers are:

  • Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody, 2020, Emerging Microbes & Infections
  • Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein, 2020, Cellular and Molecular Immunology
  • Identification of Human Single-Domain Antibodies against SARS-CoV-2, 2020, Cell Host & Microbe
  • Linear epitopes of SARS-CoV-2 spike protein elicit neutralizing antibodies in COVID-19 patients, 2020, Cellular and Molecular Immunology
  • RBD-Fc-based COVID-19 vaccine candidate induces highly potent SARS-CoV-2 neutralizing antibody response, 2020, Signal Transduction and Targeted Therapy

Best Publications

  • Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody.

    Xiaolong Tian;Cheng Li;Ailing Huang;Shuai Xia

  • Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein.

    Shuai Xia;Yun Zhu;Meiqin Liu;Qiaoshuai Lan

  • Identification of Human Single-Domain Antibodies against SARS-CoV-2.

    Yanling Wu;Cheng Li;Shuai Xia;Xiaolong Tian

  • Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies.

    Tianlei Ying;Lanying Du;Tina W. Ju;Ponraj Prabakaran

  • Linear epitopes of SARS-CoV-2 spike protein elicit neutralizing antibodies in COVID-19 patients.

    Yang Li;Dan-Yun Lai;Hai-Nan Zhang;He-Wei Jiang

  • A novel coronavirus (2019-nCoV) causing pneumonia-associated respiratory syndrome.

    Shibo Jiang;Shuai Xia;Tianlei Ying;Lu Lu

  • RBD-Fc-based COVID-19 vaccine candidate induces highly potent SARS-CoV-2 neutralizing antibody response.

    Zezhong Liu;Wei Xu;Shuai Xia;Chenjian Gu

  • Human-IgG-Neutralizing Monoclonal Antibodies Block the SARS-CoV-2 Infection.

    Jinkai Wan;Shenghui Xing;Longfei Ding;Yongheng Wang

  • Middle East respiratory syndrome coronavirus (MERS-CoV) entry inhibitors targeting spike protein

    Shuai Xia;Qi Liu;Qian Wang;Zhiwu Sun

  • Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody

    Tianlei Ying;Ponraj Prabakaran;Lanying Du;Wei Shi

  • Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns

    Harshani Nadeeshani;Jinyao Li;Tianlei Ying;Baohong Zhang

  • Soluble Monomeric IgG1 Fc

    Tianlei Ying;Weizao Chen;Rui Gong;Yang Feng

  • Enhancement versus neutralization by SARS-CoV-2 antibodies from a convalescent donor associates with distinct epitopes on the RBD.

    Yunjiao Zhou;Zezhong Liu;Shibo Li;Wei Xu

  • Prophylaxis With a Middle East Respiratory Syndrome Coronavirus (MERS-CoV)–Specific Human Monoclonal Antibody Protects Rabbits From MERS-CoV Infection

    Katherine V. Houser;Lisa Gretebeck;Tianlei Ying;Yanping Wang

  • Receptor-binding domain-specific human neutralizing monoclonal antibodies against SARS-CoV and SARS-CoV-2.

    Fei Yu;Rong Xiang;Xiaoqian Deng;Lili Wang

  • Single-Domain Antibodies As Therapeutics against Human Viral Diseases.

    Yanling Wu;Shibo Jiang;Tianlei Ying

  • Efficacy of antibody-based therapies against Middle East respiratory syndrome coronavirus (MERS-CoV) in common marmosets.

    Neeltje van Doremalen;Darryl Falzarano;Tianlei Ying;Emmie de Wit

  • Engineered Soluble Monomeric IgG1 CH3 Domain GENERATION, MECHANISMS OF FUNCTION, AND IMPLICATIONS FOR DESIGN OF BIOLOGICAL THERAPEUTICS

    Tianlei Ying;Weizao Chen;Yang Feng;Yanping Wang

  • Exceptionally Potent and Broadly Cross-Reactive, Bispecific Multivalent HIV-1 Inhibitors Based on Single Human CD4 and Antibody Domains

    Weizao Chen;Yang Feng;Ponraj Prabakaran;Tianlei Ying

  • Pharmacodynamics of long-acting folic acid-receptor targeted ritonavir boosted atazanavir nanoformulations

    Pavan Puligujja;Shantanu S. Balkundi;Lindsey M. Kendrick;Hannah M. Baldridge

Frequent Co-Authors

Shibo Jiang
Shibo Jiang Fudan University
Dimiter S. Dimitrov
Dimiter S. Dimitrov University of Pittsburgh
Lu Lu
Lu Lu Fudan University
Wei Li
Wei Li Chinese Academy of Sciences
Jun Lu
Jun Lu Zhejiang University
Zhenghong Yuan
Zhenghong Yuan Fudan University
Wei Xu
Wei Xu Fudan University
Michel C. Nussenzweig
Michel C. Nussenzweig Rockefeller University
Jin Xie
Jin Xie ShanghaiTech University
Lanying Du
Lanying Du Georgia State University

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